Vision Research

Active

Assistance listing
93.867
Agency
Grant awards
16,704 $17,470,079,274 in federal obligations

Program facts

Also known as
NEI
Assistance types
  • Project Grant
  • Cooperative Agreement
  • Block Grant
Treasury account
  • 75-0887-0-1-552
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The National Eye Institute (NEI), part of the Department of Health and Human Services National Institutes of Health, funds vision research across a broad portfolio with Assistance Listing 93.867, most recently awarding grants on May 1, 2027.

The program funds fundamental and applied research to understand eye and visual system biology, prevent and treat vision diseases, and support vision rehabilitation—spanning molecular and cellular vision science, retinal degeneration, glaucoma, age-related macular degeneration, corneal disease, visual development and neuroscience, and clinical vision research. Recent awards demonstrate the scope: gene therapy for inherited retinal degenerations, visual system circuit mapping in primates and rodents, mechanisms of photoreceptor maintenance and renewal, development of retinal prosthetics and implantable devices, and clinical studies of diabetic retinopathy screening and oculomics. The program emphasizes training and workforce development alongside research.

The portfolio is dominated by Project Grants (96 percent, 15,998 awards) with smaller shares of Block Grants (3 percent, 508 awards) and Cooperative Agreements (1 percent, 198 awards). Combined federal funding stands at $17.47 billion across 16,704 awards since 1974. The NEI funds 4,801 awards totaling $11.81 billion federal dollars obligated—the largest single funder by far. Broader NIH mechanisms contribute an additional $4.92 billion across 11,515 awards; other NIH institutes (NINDS, NIMH) and HHS agencies fund smaller tranches, collectively accounting for less than 5 percent of the program's total investment. Recent award magnitudes for individual grants range from $37 thousand (fellowship training) to over $2.27 million (large R01 programs), with typical R01 and R21 awards in the range of $400 thousand to $700 thousand.

Active grant opportunities remain available. The NEI Translational Research Program for Therapeutics (R61/R33, PAR-28-072) supports product development for biological, pharmaceutical, and device therapies for visual system disease, with a due date of November 16, 2029. The NEI New Innovator Award (DP2, PAR-26-087) funds exceptional early-career investigators proposing novel vision research without preliminary data requirements. The NEI Center Core Grant (P30, PAR-26-113) supports shared research infrastructure for groups of R01-funded investigators. Collaborative mechanisms including the NEI Collaborative Clinical Vision Research (UG1, PAR-26-119) and the BRAIN Initiative Integrative Team-Research program (RM1, RFA-NS-27-002) remain open. Award activity has declined moderately in 2026–2027 (234 and 16 awards respectively year-to-date), suggesting normal annual variability after consistent annual funding of 357–362 awards during 2023–2024.

Objective and description

Objective

The mission of the National Eye Institute is to eliminate vision loss and improve quality of life through vision research. The goal is to drive innovative research to understand the eye and visual system, prevent and treat vision diseases, and expand

Description

The mission of the National Eye Institute is to eliminate vision loss and improve quality of life through vision research. To achieve this mission, NEI provides leadership to: 1) Drive innovative research to understand the eye and visual system, prevent and treat vision diseases, and expand opportunities for people who are blind or require vision rehabilitation; 2) Foster collaboration in vision research and clinical care to develop new ideas and share knowledge across other fields; 3) Recruit, inspire, and train talented new generation of individuals to expand and strengthen the vision workforce; 4) Educate health care providers, scientists, policymakers, and the public about advances in vision research and their impact on health and quality of life.

Eligibility

Applicant eligibility

Eligible organizations determined at the NOFO level.

Beneficiary eligibility

Any nonprofit or for-profit organization, company, or institution engaged in biomedical research.

Uses of assistance

Research Grants provide funds for salaries, equipment, supplies, travel, and other expenses associated with scientific investigation relevant to program objectives.

Length and time phasing of assistance

Up to five years for research grants and cooperative agreements, Career Development Awards, Core Grants, individual predoctoral NRSAs, and institutional NRSAs. Up to three years for Academic Research Enhancement Awards and NRSA individual postdoctoral awards. Clinical Study Planning Grants: one year. SBIR: Normally, Phase I awards are for six months; normally, Phase II awards are for two years. STTR: Normally, Phase I awards are for one year; normally, Phase II awards are for two years. Loan Repayment Program Awards are for two years with the opportunity for renewal.

How to apply

Preapplication coordination

Applicants for core grants, clinical study planning grants, cooperative agreements, small research grants for data analyses, and bioengineering research partnerships should seek preapplication coordination through contact with the National Eye Institute staff. All staff may be contacted at (301) 451-2020. Applicants for planning to submit a research project grant application requesting $500,000 or more in direct costs for any year are required to discuss their eligibility with the NEI staff, at (301) 451-2020.

Criteria for selecting proposals

The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project; (2) Availability of funds; and (3) Relevance to program priorities.

Award procedure

Applications are reviewed initially for scientific and technical merit. A second level review of the programmatic relevance of applications is provided by the National Advisory Eye Council. Final approval is made by the Director, National Eye Institute. Formal award notices are transmitted to the appropriate institutional official.

Time to approval or disapproval

Approximately nine months for Research Grants, Individual Career Development Awards, Clinical Study Planning Grants, cooperative clinical studies or conferences, Core Grants, and NRSA Institutional applications; from six to seven months for NRSA individual applications; and for SBIR, about eight months.

Renewals

Renewals of research grant or cooperative agreement support are by competitive application and review. Individual Career Development Awards, Clinical Study Planning Grants, NEI Translational Research Program on Therapy for Visual Disorders, and NEI Research Grants for Secondary Data Analysis are non-renewable.

Appeals

A principal investigator may question the substantive or procedural aspects of the review of his/her application by communicating with the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH homepage http://grants.nih.gov/grants/guide/notice-files/NOT-OD-11-064.html

Grant opportunities

Opportunity Status Posted Applications due
Investigator-Focused Award (Parent R35) PAR-28-037 Forecasted —
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) PAR-27-040 Forecasted —
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional) PAR-27-039 Forecasted —
Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed) RFA-AI-27-014 Open
NEI Center Core Grant for Vision Research (P30 Clinical Trial Not Allowed) PAR-26-113 Past —
NEI Collaborative Clinical Vision Research (UG1 - Clinical Trial Optional) PAR-26-119 Past —
Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional) PAR-27-003 Open
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed) RFA-LM-28-001 Open
Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed) PA-27-030 Open
NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional) PA-26-002 Open
NIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed) PA-27-036 Open
NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed) PA-27-035 Open
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed) PAR-27-081 Open
INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed) RFA-OD-27-003 Open
INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed) RFA-OD-27-004 Open
NEI New Innovator Award (DP2 Clinical Trial Not Allowed) PAR-26-087 Past —
Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional) PAR-27-072 Open
NEI Translational Research Program for Therapeutics (R61/R33 Clinical Trial Not Allowed) PAR-28-072 Open
Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) PAR-27-022 Open
BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed) RFA-NS-27-002 Open
BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed) RFA-NS-28-010 Open
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-26-001 Open
Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-27-067 Open
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science 25-542 Closed
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) PA-27-100 Open
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional) PA-27-102 Open
NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional) PA-27-101 Open
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required) PAR-27-078 Open
NIH Research Education Program - Courses, Curriculum & Methods (Parent R25 - Clinical Trial Not Allowed) PA-27-034 Open
Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed) PA-27-037 Open
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional) PAR-27-098 Open
Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Studies (U01 Clinical Trial Not Allowed) RFA-AR-25-013 Closed
Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Clinical Trials (UH3 Clinical Trial Optional) RFA-AR-25-014 Closed
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed) RFA-DC-27-004 Open
Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed) PAR-25-442 Open
NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed) PAR-27-077 Open
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) RFA-NS-27-007 Open
Small Business Translator: MedTech and Digital Health Technologies FOR-NS-25-017 Past —
Stimulating Access to Research in Residency (StARR) (R38 Independent Clinical Trial Not Allowed) RFA-HL-26-012 Open
Accelerating Product Excellence in Innovation and for Clinical Adoption (APEx) (U24 Clinical Trial Not Allowed) RFA-DE-27-002 Closed
BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed) RFA-DA-27-004 Open
Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) PAR-25-415 Open
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) PAR-25-322 Open
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required) PAR-25-323 Closed
HEAL Initiative: Limited Competition for the HEALthy Brain and Child Development (HBCD) Study - Consortium Administrative Core and Data Coordinating Center (U24 Clinical Trial Not Allowed) RFA-DA-27-014 Closed
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed) PAR-25-414 Open
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) PA-25-425 Open
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) PA-25-422 Open
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) PA-25-423 Open
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) PA-25-426 Open
Show 40 more

Latest 50 listed here. See the rest on GovTribe.

Grant awards

Award Recipient Federal obligations Awarded
The role of astrocyte neuromodulation in cortical plasticity and learning F31EY038632 The Pennsylvania State University $37,168
Mechanisms of global visual stability across eye movements F32EY038561 New York University $79,780
A bidirectional BCI framework for visual cortical prosthesis development with cross-subject encoder translation F31EY039593 Carnegie-Mellon University $50,114
HDAC3/HK2 axis in endothelial metabolic reprogramming and pathological retinal angiogenesis. F31EY039536 University Of Arkansas For Medical Sciences $40,778
Deciphering glaucoma neurovascular dysfunction: identifying and validating endothelial mediators with ligandomics F31EY039088 Baylor College Of Medicine $100,228
The impact of GΑQ signaling on intraocular pressure F31EY039120 Trustees Of Indiana University $34,384
Ultrastructural development and regeneration of nodes of ranvier F32EY039079 The Regents Of The University Of California $153,560
Elucidation the epigenetic and transcriptional landscape of spinocerebellar type 7 retinal degeneration F30EY039130 University Of California Irvine $96,358
Defining the ocular microbiome and immune landscape of trachoma-endemic populations to inform disease risk F30EY039106 The Regents Of The University Of California. San Francisco $86,714
The role of the RPE in neurogenesis and cell fate in retinal ganglion cells F32EY038564 The Trustees Of Columbia University In The City Of New York $79,348

Latest 10 of 16,704 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 796 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $633,865,357
FY2025 $1,055,918,297
FY2024 $1,122,470,156
FY2023 $1,372,167,133
FY2022 $1,473,695,801
FY2021 $1,290,699,657
FY2020 $653,471,103
FY2019 $632,276,329
FY2018 $606,847,871
FY2017 $569,923,819
FY2016 $566,601,206
FY2015 $543,097,575
FY2014 $550,462,135
FY2013 $537,477,499
FY2012 $577,809,365
FY2011 $574,477,581
FY2010 $581,257,955
FY2009 $574,451,239
FY2008 $318,347,244
FY2007 $354,913,366
FY2006 $522,584,091
FY2005 $529,484,412
FY2004 $516,827,705
FY2003 $492,205,668
FY2002 $448,558,185
FY2001 $214,927,924
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Quick answers

What is Assistance Listing 93.867?

Assistance Listing 93.867 is Vision Research, a federal grant program run by National Institutes of Health (Department of Health and Human Services).

What is the CFDA number for Vision Research?

Its CFDA number is 93.867: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.867 awarded?

16,704 grant awards under 93.867 have obligated $17,470,079,274 in federal funds to 796 recipients.

Who receives the most funding from 93.867?

The recipients obligated the most under Vision Research are The Johns Hopkins University ($597,687,467), Jaeb Center For Health Research Foundation, Inc. ($452,997,750) and The Leland Stanford Junior University ($386,056,259).

How much did 93.867 obligate in fiscal year 2025?

Grants under 93.867 obligated $1,055,918,297 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.867?

40 of the latest 50 opportunities under 93.867 are open or forecasted. The latest, Investigator-Focused Award (Parent R35), was posted on July 30, 2026.

On GovTribe

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