Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)

Open Posted

Opportunity number
PAR-27-078
Agency
Applications due
Award size
Up to $375,000

Opportunity facts

Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Higher Education Inst. (Private)
  • Higher Education Inst. (Public)

Opportunity details come from Grants.gov. Updated .

About this opportunity

Written by GovTribe AI ·

The National Institute on Aging, together with the National Eye Institute, National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Institute on Alcohol Abuse and Alcoholism, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute on Deafness and Other Communication Disorders, National Institute on Drug Abuse, National Institute of Mental Health, National Institute of Nursing Research, National Institute on Minority Health and Health Disparities, and National Cancer Institute, is soliciting applications for investigator-initiated mechanistic and minimal-risk clinical trials under the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 activity code), with applications due October 25, 2027. Eligible applicants are accredited public or nonprofit private institutions awarding baccalaureate or advanced degrees in health professions or biomedical sciences that have received no more than $6 million per year in NIH support (direct and F&A costs combined) in 4 of the last 7 fiscal years; the $6 million funding limit applies to the institution as a whole when composed of multiple schools and colleges. Non-domestic entities and non-domestic components of U.S. organizations are not eligible. Applicants may request up to $375,000 in direct costs for a maximum 3-year project period. Minimal-risk clinical trials are defined as those not requiring FDA oversight, not intended to formally establish efficacy, and posing low risks of physical or psychological harm. Primary investigators must hold appointments at health professional or graduate schools. The research team must be composed primarily of health professional, undergraduate, and graduate students with documented involvement in experimental design, data collection, analysis, and dissemination through presentations and publications. Applications must include a signed Provost letter verifying institutional eligibility, biographical sketches highlighting prior experience supervising student researchers, and a Data Management and Sharing Plan. Multiple application due dates are available: July 10, 2026; October 25, 2026; February 25, 2027; and June 25, 2027 (all by 5:00 PM local time). Scientific Merit Review occurs in November 2026, March 2027, July 2027, and March 2028, with Advisory Council Review in January 2027, May 2027, October 2027, and May 2028, and earliest start dates for awards are April 2027, July 2027, December 2027, and July 2028 respectively. The program supports small-scale research grants at institutions that do not receive substantial NIH funding, with an emphasis on providing biomedical research experiences primarily for health professional, undergraduate, and graduate students and enhancing the research environment at applicant institutions.

Synopsis

The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for health professional, undergraduate and graduate students and enhancing the research environment at applicant institutions.Eligible institutions must award baccalaureate or advanced science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F & A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the schools and colleges within the institution as a whole.Help determining the Organization Funding Level can be found here or https://grants.nih.gov/grants/funding/r15.htmThis REAP Notice of Funding Opportunity (NOFO) supports investigator-initiated mechanistic and/or minimal risk clinical trials addressing the mission and research interests of the participating NIH institutes. For purposes of this NOFO, minimal risk clinical trials are defined as those that do not require FDA oversight, do not intend to formally establish efficacy, and have low risks to potentially cause physical or psychological harm.

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Files

File Type Posted
PAR-27-078-Full-Announcement.html HTML file
PKG00292999.pdf PDF

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