The Regents Of The University Of California. San Francisco

The Regents of the University of California, San Francisco, operating through its Controller's Office, is a U.S. government educational institution and recipient of federal research and clinical service funding across 179 customer agencies—functioning as a prime contractor and grant recipient on the vast majority of its awards (85% prime), with a smaller sub-award footprint (15%). UCSF operates full-and-open, without set-asides, leveraging its academic medical center and research mission to compete across the entire federal landscape.

UCSF's federal footprint is primarily research and clinical services. The vendor delivers grant-funded biomedical research (grant work dominant), clinical trials, clinical service delivery, and academic training across its Schools of Medicine, Nursing, Pharmacy, Dentistry, and graduate programs. Representative recent prime contract work includes a $1.41 million fixed-price definitive contract from the Food and Drug Administration awarded September 2026 for scalable monitoring procedures for generative AI-based medical devices, running through September 2028 at Silver Spring, Maryland. On the grant side, UCSF acts as recipient for NIH project grants spanning basic science (structural biology, cell signaling, immunology), translational research (drug discovery, therapeutic development), and clinical investigation (randomized trials, observational cohorts, health services research). Recent NIH grants include $2.255 million (September 2026) from the National Institute of General Medical Sciences for integrative structure modeling of biomolecular complexes; $7.063 million (September 2026) from the Defense Health Agency for a clinical trial network probing mechanistic pathways of long COVID; and $1.869 million (September 2026) from SAMHSA's Center for Mental Health Services to establish a center of excellence for eating disorders training.

Customer concentration reflects UCSF's alignment with federal research priorities. The top five funding agencies account for 46% of recent awards. The National Cancer Institute leads by dollar value ($560.8 million combined potential value across 766 awards), followed by the National Institute of Allergy and Infectious Diseases ($277.9 million across 614 awards), the National Heart Lung and Blood Institute ($260 million across 565 awards), Veterans Affairs VISN 21 ($104.5 million across 281 awards), and the National Institute on Drug Abuse ($58.7 million across 176 awards). The disparity between award count and dollar value rankings—particularly for VA VISN 21, which ranks fourth by value but well below the top agencies by count—signals smaller-value, higher-frequency VA clinical and research task orders.

UCSF holds a Basic Ordering Agreement with the Bureau of Medicine and Surgery (Defense) executed May 2026, running through May 2036, under which future orders for biomedical research, clinical trials, clinical services, and health services may be placed. The BOA establishes no ceiling and obligates no funds; it sets the framework for task orders issued over ten years. Place of performance is San Francisco with subordinate sites as required for multi-site clinical trials and research coordination. UCSF also issues delivery orders against multiple IDCs and BOAs, with the top five parent vehicles carrying 383 task orders and $56.3 million in combined potential value—including an indefinite delivery contract with 136 task orders ($3.8 million combined value) and a VA BOA with 96 task orders ($34.6 million).

Activity has fluctuated year over year: 539 awards in FY2023, climbing to 901 in FY2024, then declining to 712 in FY2025 and 559 in FY2026. This reflects the episodic nature of research funding—grants and contracts terminate and recompete rather than renew continuously. A recompete cliff looms: 920 awards (combined potential value $74.9 million) reach ultimate completion in the next twenty-four months and face recompete risk. Service Contract Inventory data, which captures federal service contracts above the $150,000 reporting threshold, shows SCI-reportable invoiced revenue of $36.8 million across four fiscal years (FY2022–FY2025), declining from $9.3 million (52.3 FTEs) in FY2022 to $7.9 million (40.9 FTEs) in FY2025. Median government-paid hourly rates on federal services contracts run $136.08/hr, with senior labor pricing reaching $387.06/hr at the 90th percentile—consistent with academic medical center cost structures. UCSF operates as a prime on most contracts, building delivery teams internally rather than routing work through subcontractors; across SCI-reportable prime records, average sub-hours share is zero percent, indicating minimal subcontract engagement on this slice of the portfolio.

UCSF is affiliated with Children's Hospital & Research Center at Oakland as a subsidiary; this relationship does not appear prominently in the recent award slice provided. The vendor's corporate parent is the State of California Controller's Office, a state government entity.