Investigator-Focused Award (Parent R35)

Forecasted Federal grant Posted

Opportunity number
PAR-28-037
Agency
Applications expected due
Award size
Not on record

Opportunity facts

Expected posting
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Tribal Organizations (Not Federally Recognized)
  • Tribal Governments (Federally Recognized)
  • Small Businesses
  • Independent School Districts
  • Other
  • Higher Education Inst. (Private)
  • City/Township Governments
  • County Governments
  • 501(c)(3) Nonprofits
  • Public or Indian Housing Auth.
  • State Governments
  • For Profit Organizations
  • Special District Governments
  • Non-501(c)(3) Nonprofits
  • Higher Education Inst. (Public)
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health forecasts publication of a Parent R35 "Investigator-Focused Award" Notice of Funding Opportunity to fund research programs for investigators at all career stages, including Early Stage Investigators, with no specific application due date identified in the forecast. The R35 is structured as an investigator's primary or only source of research funding from the awarding Institute or Center rather than support for a pre-defined project, providing funding stability and scientific freedom to pursue ambitious and innovative research within the IC's mission.

Eligible applicants span a broad range: higher education institutions (public and private), 501(c)(3) nonprofits, state and local governments, small businesses, Indian tribal governments (federally recognized and non-federally recognized), independent school districts, for-profit organizations, public or Indian housing authorities, and faith-based or community-based organizations. The R35 award model emphasizes investigator flexibility to follow science as it evolves, reduced pressure to maintain continuous new grant streams, and capacity to devote time to research, mentoring, and scientific service beyond grant administration.

The opportunity aligns with multiple parent grant programs. The underlying Cancer Detection and Diagnosis Research program (CFDA 93.394) supports screening, early detection, diagnostic techniques, and resources including tissue banks for cancer research. The Trans-NIH Research Support program (CFDA 93.310) funds biomedical and behavioral research across the full spectrum of NIH's scientific mission. The Cancer Treatment Research program (CFDA 93.395) develops and evaluates cancer therapy modalities across surgery, radiotherapy, chemotherapy, biological therapies, stem cell transplantation, and supportive care. The Cancer Cause and Prevention Research program (CFDA 93.393) funds mechanistic and applied research on carcinogenesis, screening, epidemiology, nutrition, immunology, chemoprevention, and clinical trials. The Environmental Health program (CFDA 93.113) supports research on how environmental exposures affect biological systems. Additional parent programs include Oral Diseases and Disorders Research (CFDA 93.121), Minority Health and Health Disparities Research (CFDA 93.307), Cancer Control (CFDA 93.399), Medical Library Assistance (CFDA 93.879), Biomedical Research and Research Training (CFDA 93.859), Cancer Research Manpower (CFDA 93.398), Cancer Biology Research (CFDA 93.396), Human Genome Research (CFDA 93.172), Cancer Centers Support Grants (CFDA 93.397), and Vision Research programs (CFDA 93.867 and 93.543).

The source does not specify award amounts, period of performance, cost share requirements, or expected number of awards. No application deadline has been set for the R35 forecast.

Forecast synopsis

The National Institutes of Health intends to publish a Parent R35 "Investigator-Focused Award" Notice of Funding Opportunity (NOFO) to fund research programs for investigators at all career stages, including Early Stage Investigators (ESIs). The Parent R35 Investigator-Focused Award is intended to provide support for an investigator's program of research within the mission of the awarding Institute or Center (IC) rather than support for a pre-defined project with specific aims.

The R35 is typically expected to be an investigator's primary (or only) source of research funding from the awarding IC.

An R35 award gives investigators funding stability and scientific freedom. With R35 support, researchers can pursue ambitious and innovative studies without the pressure of constantly seeking new funding streams. Key benefits include:

  • Providing flexibility to follow the science as it evolves within the awarding IC's mission.
  • Providing stability to take on important, challenging research questions.
  • Allowing recipients to devote sufficient time to research, mentoring, and scientific service, and less time to grant administration.
  • Providing a high potential for scientific breakthroughs by enabling investigators to think broadly and pursue promising opportunities.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

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