Cancer Research Manpower
Active
- Assistance listing
- 93.398
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Grant awards
- 12,555 $5,392,510,120 in federal obligations
Program facts
- Also known as
- Cancer Manpower Grants
- Assistance types
-
- Project Grant
- Block Grant
- Cooperative Agreement
- Treasury account
-
- 75-0849-0-1-550
- More information
Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.
About this program
The Department of Health and Human Services National Institutes of Health administers the Cancer Research Manpower program (CFDA 93.398) to provide biomedical training opportunities for individuals pursuing careers in basic, clinical, and prevention research relevant to the National Cancer Program, with the most recent grant award on March 4, 2027.
The program funds predoctoral and postdoctoral fellowships (predominantly F31 and F30 awards), research training grants, and career development awards spanning up to five years with potential renewals. Recent awards support dissertation research in cancer biology, immunotherapy, tumor microenvironment mechanisms, and translational oncology. Representative funded projects include characterization of chemotherapy resistance in gliomas (F31CA301899, $47,383), investigation of T-cell metabolic reprogramming in leukemia (F31CA301702, $48,642), and development of HPV vaccination strategies in rural health professional shortage areas (F31CA318452, $50,114). The portfolio reflects active training in mechanism-driven cancer research across hematologic and solid tumors.
The program has maintained steady output at roughly 270–350 awards per year over the past five years. Cumulative federal dollars obligated total $5.39 billion across 12,555 awards since 1975. The National Cancer Institute dominates funding, with 4,576 awards and $3.64 billion in federal dollars, while the broader NIH system contributes an additional $1.6 billion through 7,588 awards. Assistance-type distribution is heavily skewed toward Project Grants (97% of awards), with Block Grants (3%) and Cooperative Agreements (less than 1%) comprising the remainder. Matching or cost-share contribution from recipients totals $230 million against the federal base.
No grant opportunities are currently open under this Assistance Listing. Active competing funding mechanisms for early-career researchers are available through companion programs including the Ruth L. Kirschstein NRSA predoctoral fellowship (F31, Parent PA-25-422), the predoctoral-to-postdoctoral transition award (F99/K00, Parent PA-27-037), and the Academic Career Excellence Award (K32, Parent PAR-27-062), all of which support mentored training and career development in cancer and biomedical research.
Objective and description
- Objective
To make available support to nonprofit and for-profit institutions interested in providing biomedical training opportunities for individuals interested in careers in basic, clinical, and prevention research important to the National Cancer Program.
- Description
To make available support to nonprofit and for-profit institutions interested in providing biomedical training opportunities for individuals interested in careers in basic, clinical, and prevention research important to the National Cancer Program.
Eligibility
- Applicant eligibility
University, college, hospital, public agency, or nonprofit research institution for institutional grants and individuals for fellowships. The applicant institution must be able to provide the staff and facilities and be responsible for the selection of trainees and overall direction of the training. Selected awardees must be citizens of the United States or be admitted to the United States for permanent residency. Career and Cancer Education awards may be given to for-profit institutions.
- Beneficiary eligibility
University, college, hospital, public agency, nonprofit research institution or for-profit institution.
- Uses of assistance
The Research Manpower program provides support for research training in all scientific fields related to cancer. The Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Fellows, are made directly to individuals for research training in biomedical sciences areas. In addition, the National Institutes of Health (NIH) will award the Ruth L. Kirschstein NRSA Institutional Research Training grants to institutions, to enable them to make NRSA awards to individuals selected by them. Each individual who receives a postdoctoral NRSA is obligated, upon termination of the award, to comply with certain service and payback provisions. Cancer Education Grants are designed to promote education programs carried out by organizations engaged in health-related education, research, or training, located in the United States, its possessions, or territories. Various Career awards are designed to sponsor the development of independent scientists. Individual short-term support for students is available under the Cancer Education Program.
- Length and time phasing of assistance
Up to 5 years.
How to apply
- Criteria for selecting proposals
The major elements in evaluating proposals include the assessment of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives.
- Award procedure
All applications are evaluated by scientific authorities for scientific and technical merit. Applications must also be reviewed by the National Cancer Advisory Board. All competitive applications compete for available funds on the basis of scientific and technical merit, program relevance, and program balance, consistent with NCI and NIH priorities and strategic plans.
- Time to approval or disapproval
Approximately 10 months.
- Renewals
Cancer Education Grants may be made for periods of up to 5 years and renewals may be submitted when appropriate. Research training grants may be renewed for additional project periods of 5 years. Only the following Career awards are renewable: K05 and K24 only a one-time renewal after a 5-year project period, and the K12 up to 5 years (Trainees 2-7 years).
- Appeals
A principal investigator (P.I.) may question the substantive or procedural aspects of the review of his/her application by communicating with the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available under the Review Criteria section of the NIH Office of Extramural Research website at http://grants2.nih.gov/grants/policy/nihgps_2003/NIHGPS_Part3.htm.
Grant opportunities
Show 40 more
Latest 50 listed here. See the rest on GovTribe.
Grant awards
Latest 10 of 12,555 listed here. See the rest on GovTribe.
Top recipients by federal obligations
| Rank | Recipient | Federal obligations | Share |
|---|---|---|---|
| 1 | Sloan-Kettering Institute For Cancer Research | $194,311,988 | 4% |
| 2 | The Univeristy Of Texas M.d. Anderson Cancer Center | $160,684,591 | 3% |
| 3 | Dana-Farber Cancer Institute, Inc. | $148,436,677 | 3% |
| 4 | The Johns Hopkins University | $135,121,664 | 3% |
| 5 | The General Hospital Corporation | $133,005,124 | 2% |
| 6 | University Of North Carolina At Chapel Hill | $130,409,914 | 2% |
| 7 | The Leland Stanford Junior University | $124,501,998 | 2% |
| 8 | The Regents Of The University Of California. San Francisco | $122,235,536 | 2% |
| 9 | The Trustees Of The University Of Pennsylvania | $121,769,105 | 2% |
| 10 | The Washington University | $96,772,292 | 2% |
10 of 378 recipients listed here. See the rest on GovTribe.
Federal obligations by fiscal year
| Fiscal year | Federal obligations |
|---|---|
| FY2026 | $206,050,438 |
| FY2025 | $321,773,135 |
| FY2024 | $374,221,901 |
| FY2023 | $422,775,812 |
| FY2022 | $461,947,837 |
| FY2021 | $408,290,284 |
| FY2020 | $202,589,207 |
| FY2019 | $187,893,650 |
| FY2018 | $177,814,764 |
| FY2017 | $164,557,124 |
| FY2016 | $163,719,523 |
| FY2015 | $161,404,868 |
| FY2014 | $162,552,855 |
| FY2013 | $163,703,415 |
| FY2012 | $168,195,717 |
| FY2011 | $182,748,387 |
| FY2010 | $188,537,068 |
| FY2009 | $195,469,546 |
| FY2008 | $81,001,875 |
| FY2007 | $139,591,003 |
| FY2006 | $175,930,440 |
| FY2005 | $174,125,926 |
| FY2004 | $170,133,871 |
| FY2003 | $158,732,830 |
| FY2002 | $137,562,638 |
| FY2001 | $77,814,717 |
Show all 26
Quick answers
What is Assistance Listing 93.398?
Assistance Listing 93.398 is Cancer Research Manpower, a federal grant program run by National Institutes of Health (Department of Health and Human Services).
What is the CFDA number for Cancer Research Manpower?
Its CFDA number is 93.398: Assistance Listing numbers were called CFDA numbers before 2018.
How much funding has Assistance Listing 93.398 awarded?
12,555 grant awards under 93.398 have obligated $5,392,510,120 in federal funds to 378 recipients.
Who receives the most funding from 93.398?
The recipients obligated the most under Cancer Research Manpower are Sloan-Kettering Institute For Cancer Research ($194,311,988), The Univeristy Of Texas M.d. Anderson Cancer Center ($160,684,591) and Dana-Farber Cancer Institute, Inc. ($148,436,677).
How much did 93.398 obligate in fiscal year 2025?
Grants under 93.398 obligated $321,773,135 in federal funds in fiscal year 2025.
Are there open grant opportunities under 93.398?
33 of the latest 50 opportunities under 93.398 are open or forecasted. The latest, Investigator-Focused Award (Parent R35), was posted on July 30, 2026.
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