Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional)

Open Posted

Opportunity number
PAR-27-076
Agency
Applications due
Award size
$499,000

Opportunity facts

Funding instrument
Grant
Category
  • Health
Eligible applicants
  • County Governments
  • Small Businesses
  • Tribal Organizations (Not Federally Recognized)
  • Other
  • Higher Education Inst. (Private)
  • Independent School Districts
  • For Profit Organizations
  • City/Township Governments
  • Special District Governments
  • Higher Education Inst. (Public)
  • Tribal Governments (Federally Recognized)
  • 501(c)(3) Nonprofits
  • Public or Indian Housing Auth.
  • Non-501(c)(3) Nonprofits
  • State Governments
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

Written by GovTribe AI ·

The National Institutes of Health is soliciting applications for the Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional), a competitive career-development award with an application due date of July 7, 2028. This opportunity is restricted to clinical researchers—physicians, dentists, nurses, and equivalent clinical doctoral degree holders with professional licensure to practice clinically in the United States—in early stages of independent careers, generally post-fellowship but pre-tenure. Non-U.S. citizens may apply if they qualify for appropriate visa status. Foreign organizations and foreign components of U.S. organizations are not eligible.

The program offers a distinctive two-phase structure combining NIH intramural and extramural support. Phase 1 provides tenure-track appointments for up to 5–7 years within the NIH Intramural Research Program with independent research budgets, full salary, and benefits. Phase 2 allows recipients to either remain within the intramural program pursuing tenure or transition to extramural research at an eligible institution, receiving up to 3 years of NIH support (R00 mechanism) contingent on securing a full-time tenure-track position and successful programmatic review. For the extramural R00 phase, direct costs are capped at $499,000 per year; intramural budgets are negotiated with sponsoring institutes. The program anticipates funding up to 5 awards per cycle.

Applications must include four letters of reference submitted by the due date. The program spans 16 participating NIH institutes and centers. Eligible applicants include county governments, small businesses, tribal organizations, higher education institutions (public and private), nonprofits (501(c)(3) and non-501(c)(3)), state governments, and public or Indian housing authorities. Review emphasizes investigator accomplishments and potential alongside research project quality, with peer review followed by secondary review by appropriate advisory councils. Scientific merit criteria include significance, innovation, investigator qualifications, approach, and specific Phase 1 milestones with alternative strategies and feasibility assessments. Selected candidates may be invited for employment interviews at NIH and must provide additional eligibility documentation. Assistance Listing numbers are 93.310 (Trans-NIH Research Support) and 21 additional CFDA numbers spanning NHLBI, NCI, NIMH, NIDDK, NICHD, and other NIH institutes.

Synopsis

This NOFO encourages applications for the Lasker Clinical Research Scholars Program. The program supports the research activities of clinical researchers during the early stages of their independent careers as they work to improve human health. The program offers the opportunity for a unique bridge between the NIH intramural and extramural research communities and contains two phases. In the first phase, Lasker Scholars will receive appointments for up to 5-7 years as tenure-track investigators within the NIH Intramural Research Program with independent research budgets. In the second phase, successful scholars will receive up to 3 years of NIH support for their research at an extramural research institute, or can remain as an investigator within the intramural program.

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Files

File Type Posted
PKG00294089.pdf PDF
PAR-27-076-Full-Announcement.html HTML file

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