Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security

Active

Assistance listing
93.318
Agency
Grant awards
339 $1,550,624,307 in federal obligations

Program facts

Also known as
Global Health
Assistance types
  • Cooperative Agreement
  • Project Grant
Treasury account
  • 75-0943-0-1-551
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Health and Human Services Centers for Disease Control and Prevention funds international infectious disease surveillance, laboratory capacity, workforce training, and outbreak response activities worldwide under Assistance Listing 93.318, with the most recent grant award on September 30, 2026.

Grant activity in this program remains steady and recent. The portfolio includes 339 awards spanning from 2014 to present, with an average of roughly 4 to 6 awards per year in recent years, accelerating to 9 awards in 2026. Combined federal dollars obligated total $1.55 billion across these awards. The program predominantly funds cooperative agreements (98% of awards, 333 of 339), with only a small share of project grants (2%). Funding concentration is substantial: CDC itself accounts for the vast majority of obligated dollars across multiple functional components within the program, with all seven distinct funding federal agencies being CDC sub-organizations.

Funded activities center on infectious disease surveillance and laboratory strengthening in low- and middle-income countries, emphasizing influenza, respiratory pathogens, and zoonotic diseases. Recent awards show this scope in practice. A cooperative agreement with the Pan American Health Organization for $27.3 million (through May 2029) supports immunization program capacity in the Americas. Uganda received a $35 million cooperative agreement (through September 2029) for HIV-related laboratory testing and diagnostics under PEPFAR. South Africa's cooperative agreement for $12.1 million (through August 2029) funds collaborative influenza and respiratory pathogen research. Smaller awards of $150 thousand to $800 thousand support surveillance and response to influenza and avian flu across the Caribbean, Kenya, and Southeast Europe. Project grants ($296 thousand to $2.2 million) fund diagnostic development—including rapid pathogen detection platforms and drug-resistant TB testing systems.

Multiple grant opportunities posted recently target global health security strengthening. CDC-RFA-JG-27-0069, posted August 14, 2026, seeks cooperative agreement applications for capacity building in global and national immunization programs (no stated deadline yet). CDC-RFA-CK-27-0244, posted August 3, 2026, funds antimicrobial resistance and healthcare-associated infection detection, surveillance, and response in low- and middle-income countries (forecast only). CDC-RFA-CK-26-0230 (posted April 16, 2026, due September 26, 2026) supports fungal disease detection and surveillance capacity. Additional opportunities targeting country-specific health security strengthening in Ghana, DRC, Kenya, Uganda, Ethiopia, Nigeria, Sierra Leone, Senegal, Tanzania, India, and Indonesia carry application deadlines between August and October 2026. Eligibility for most recent opportunities is unrestricted or open to 501(c)(3) nonprofits, higher education institutions, state and local governments, and other entity types; foreign applicants are eligible dependent on the specific NOFO.

Objective and description

Objective

CDC's global health efforts are to assist Ministries of Health and other international partners to plan, manage effectively, and evaluate public health programs; achieve U.S. Government program and international organization goals to improve health,

Description

CDC's global health efforts are to assist Ministries of Health and other international partners to plan, manage effectively, and evaluate public health programs; achieve U.S. Government program and international organization goals to improve health, including disease eradication and elimination targets; expand CDC's global health programs that focus on the leading causes of worldwide mortality, morbidity and disability, including chronic disease and injuries; generate and apply new knowledge to achieve health goals; and, strengthen health systems and their impact.

Eligibility

Applicant eligibility

Eligibility also extends to foreign applicants. Dependent on the Notice of Funding Opportunity (NOFO), eligibility may range from open, competitive, limited, or single eligibility in accordance with authorizing legislation.

Beneficiary eligibility

This will benefit individuals worldwide, including in the U.S., through collaborations with national Ministries of Health and other organizations/institutions. This is only for non-research activities supported by CDC/ATSDR. For the definition of research, please see http://www.cdc.gov/od/science/quality/resources.

Uses of assistance

Support the implementation of programs and activities focusing on protecting and improving health globally through regional, national, and local partnerships to develop, implement and strengthen public health surveillance, health information systems (including monitoring and evaluation), public health laboratory capacity, workforce development, as well as systems and capacities for the prevention, detection, response, and control of infectious and non-communicable diseases, injury prevention efforts and public health emergencies. Support must also be aimed at building upon existing public health infrastructure focusing on country priorities that are of mutual interest to CDC in order to strengthen regional and national partnerships, public health capacity, leadership, strategic collaboration and integrated health programming through national ministries of health, national public health networks and inter-sectorial co-operation and collaborations with other health organizations, non-governmental health organizations, academic institutions and community groups as appropriate to accomplish program activities. In addition, projects must also consider monitoring and evaluation of overall program performance and the progress of projects or activities.

Use restrictions

Recipients may not use funds for clinical care. • Recipients may only expend funds for reasonable program purposes, including personnel, travel, supplies, and services, such as contractual. • Recipients may not generally use HHS/CDC/ATSDR funding for the purchase of furniture or equipment. Any such proposed spending must be identified in the budget. • The direct and primary recipient in a cooperative agreement program must perform a substantial role in carrying out project objectives and not merely serve as a conduit for an award to another party or provider who is ineligible. • Reimbursement of pre-award costs is not allowed.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity Announcements (NOFOs). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific and technical merit by objective or peer review, availability of funds, and relevance of program priorities and the priorities of CDC.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Deadlines

Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.

Renewals

Cooperative agreement period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.

Grant opportunities

Opportunity Status Posted Applications due
Capacity Building for National Immunization Programs in the Eastern Mediterranean Region CDC-RFA-JG-27-0070 Forecasted —
Capacity Building for Global, Regional, and National Immunization Programs CDC-RFA-JG-27-0069 Forecasted —
DHQP Global NOFO CDC-RFA-CK-27-0244 Forecasted —
Advancing Global Capacity to Detect and Respond to Fungal Diseases CDC-RFA-CK-26-0230 Closed
Advancing Outbreak Detection, Notification, and Response Capacity by Implementing 7-1-7 in Partner Countries CDC-RFA-JG-26-0214 Closed
Preventing global health threats by strengthening surveillance systems to accelerate outbreak detection, notification, and response CDC-RFA-JG-26-0113 Closed
Protecting and Improving Global Health Security by Engaging Local Partners: Strengthening and Sustaining Public Health Systems in Ghana CDC-RFA-JG-26-0047 Closed
Enhancing global laboratory systems to safely manage biological risks, deploy diagnostics, and sequence pathogens to improve capacities for global health threat response and detection CDC-RFA-JG-26-0058 Closed
Strengthening public health efforts to protect and improve health in the Democratic Republic of the Congo (DRC) CDC-RFA-JG-26-0044 Closed
Sustaining Global Health Security to protect and improve public health in Kenya CDC-RFA-JG-26-0055 Closed
Strengthening Global Health Security by improving public health capacity to detect, notify, and respond to disease outbreaks globally CDC-RFA-JG-26-0056 Closed
Strengthening global health security through local partnerships in Uganda CDC-RFA-JG-26-0054 Closed
Expanding global health security through local partnerships in Ethiopia CDC-RFA-JG-26-0046 Closed
Expanding global health security through local partnerships in Nigeria CDC-RFA-JG-26-0043 Closed
Strengthening Global Health Security through local partnerships in Sierra Leone CDC-RFA-JG-26-0050 Closed
Expanding Global Health Security through local partnerships in Senegal CDC-RFA-JG-26-0048 Closed
Expanding global health security though local partnerships in Tanzania CDC-RFA-JG-26-0052 Closed
Strengthening global health security in India to contain public health threats and accelerate outbreak response CDC-RFA-JG-26-0051 Closed
Expanding global health security through local partnerships in Indonesia CDC-RFA-JG-26-0053 Closed
Improving global health security in Côte d'Ivoire to stop the spread of infectious disease CDC-RFA-JG-26-0042 Closed
Advancing national epidemiologic, surveillance, research and laboratory capacities and systems to support a sustainable and resilient response to HIV/TB and related public health threats in the Kingdom of Eswatini under PEPFAR CDC-RFA-JG-25-0071 Closed
Advancing Diagnostic Network Optimization, Stepwise Laboratory Accreditation, and Integrated One Health Specimen Transport in Liberia CDC-RFA-JG-24-0134 Closed
Achieving Global Health Security Through Strengthening Public Health Emergency Preparedness and Management Platforms in Liberia CDC-RFA-JG-24-0135 Closed
Public Health Partnerships to Accelerate Prevention and Control of Infectious Diseases and Emerging Public Health Threats in China and Globally CDC-RFA-JG-24-0131 Closed
Strengthening Capacity of Central Asia and Eastern Europe Countries to Implement Sustainable and Effective HIV/AIDS Prevention, Care, and Treatment and Health Security Programs under PEPFAR CDC-RFA-GH-24-0069 Closed
Strengthening immunization program implementation in sub-national consequential geographies CDC-RFA-GH-24-0058 Closed
Global Emergency Response and Recovery Partner Engagement: Expanding Efforts and Strategies to Improve Rapid Response to Public Health Emergencies Globally CDC-RFA-GH-23-0042 Closed
Strengthening Global Capacity for Molecular Surveillance and Outbreak Response for Enteric Diseases CDC-RFA-CK-23-0003 Closed
Global Emergency Response and Recovery Partner Engagement: Expanding Efforts and Strategies to Improve Rapid Response to Public Health Emergencies Globally CDC-RFA-GH22-2267 Past —
Reducing the Tuberculosis Burden in U.S. Bound Populations from the Philippines CDC-RFA-CK22-2201 Closed
Strategic Planning: Southeast Asia CDC-RFA-CD21-2105 Closed
Strategic Planning: South America CDC-RFA-CD21-2102 Closed
Strategic Planning: Middle East/North Africa CDC-RFA-CD21-2104 Closed
Strategic Planning: Eastern Europe/Central Asia CDC-RFA-CD21-2103 Closed
Global Noncommunicable Disease Prevention and Health Promotion CDC-RFA-GH21-2180 Closed
Partnering with Regional Institutes to Strengthen Essential Public Health Functions in Vietnam CDC-RFA-GH21-2179 Closed
Protecting and Improving Health Globally: Building and Strengthening Public Health Systems, Capacity and Security - Advancing Regional Health Security for Prevention and Control of Communicable & Non-Communicable Diseases in the Caribbean CDC-RFA-GH21-2177 Closed
Strengthening the healthcare system of Vietnam through capacity building, policy development and quality improvement of disease surveillance, laboratory and clinical services. CDC-RFA-GH21-2166 Closed
Capacity Building and Strengthening of Hospital Infection Control to detect, prevent and respond to antimicrobial resistance in India CDC-RFA-GH21-2173 Closed
Strengthening detection, prevention and response to infectious disease threats in Uzbekistan CDC-RFA-GH21-2169 Closed
Strengthening detection, prevention and response to infectious disease threats in Kazakhstan CDC-RFA-GH21-2167 Closed
Technical Collaboration to Strengthen and Expand Capacity to Detect, Prevent, Respond and Mitigate the Effects of Public Health Threats of National and Global Importance with the Ministry of Public Health (MoPH) in the Kingdom of Thailand CDC-RFA-GH21-2106 Closed
Technical Collaboration to Strengthen Bangkok Metropolitan Administration Capacity to Detect, Prevent, Respond, Monitor, and Mitigate The Effects of Public Health Threats In The Kingdom of Thailand. CDC-RFA-GH21-2107 Closed
Global Healthcare Detection and Response CDC-RFA-CK21-2104 Closed
Surveillance and Response to Seasonal and Pandemic Influenza by Regional Offices of the World Health Organization CDC-RFA-IP21-2102 Closed
Strengthening animal health systems to enhance prevention, detection and response to emerging zoonotic diseases CDC-RFA-CK21-2105 Closed
Strengthening Public Health Responses and Accelerating HIV/AIDS Program for the Sustainable Provision of Comprehensive HIV/AIDS Services in Tigray Regional State of the Federal Democratic Republic of Ethiopia under PEPFAR CDC-RFA-GH21-2178 Closed
Globally coordinated safety monitoring for COVID-19 vaccines CDC-RFA-CK21-2107 Closed
Surveillance and Response to Avian and Pandemic Influenza by National Health Authorities outside the United States CDC-RFA-IP21-2101 Closed
Show 39 more

Latest 49 listed here. See the rest on GovTribe.

Grant awards

Award Recipient Federal obligations Awarded
Development of an automated, compact sample-to-sequencer ready system for extensively/multi drug-resistant TB detection R43JG000001 Redbud Labs, Inc. $45,162
Optimized zanamivir microarray patch (map) formulation for single application treatment of the flu R43IP001280 Tsrl, Inc. $299,608
Rapid and highly multiplexed pathogen detection for sepsis patients with compressed sensing and digital PCR R43CK000714 Anvil Diagnostics Inc. $296,185
Rapid, on-site shiga toxin-producing e. Coli test in irrigation water R43CK000708 Lynntech Inc. $249,190
Surveillance and response to avian and pandemic influenza and other infectious disease threats in kenya - see… NU51IP000978 HJF Medical Research International Inc. $191,000
Strengthening of epidemic intelligence for influenza and respiratory diseases at national and subnational levels in… NU51IP000958 Ministry Of Health-Centers For Disease Control And Prevention $200,000
Surveillance and response to avian and pandemic influenza and other infectious disease threats in the caribbean… NU51IP000955 Caribbean Public Health Agency $150,000
Surveillance and response to avian and pandemic influenza and other infectious disease threats through integration of… NU51IP000951 Fondacioni Secid $800,000
A high-throughput automated platform for rapid isolation and testing of salmonella R43CK000713 Microsensor Labs, LLC $306,872
A novel remote blood separation device for at-home plasma collection for HIV-1 testing R44PS005271 Lo Biosciences, Inc. $2,185,500

Latest 10 of 339 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 168 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $11,547,779
FY2025 $38,236,318
FY2024 $169,958,247
FY2023 $329,729,988
FY2022 $708,379,771
FY2021 $548,678,536
FY2020 $512,174,263
FY2019 $158,639,459
FY2018 $90,695,262
FY2017 $182,624,309
FY2016 $147,656,297
FY2015 $122,147,890
FY2014 $1,089,228
Show all 13

Quick answers

What is Assistance Listing 93.318?

Assistance Listing 93.318 is Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security?

Its CFDA number is 93.318: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.318 awarded?

339 grant awards under 93.318 have obligated $1,550,624,307 in federal funds to 168 recipients.

Who receives the most funding from 93.318?

The recipients obligated the most under Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security are African Field Epidemiology Network LTD ($261,102,949), Association Of Public Health Laboratories, Inc. (The) ($149,133,822) and The Task Force For Global Health, Inc. ($113,925,746).

How much did 93.318 obligate in fiscal year 2025?

Grants under 93.318 obligated $38,236,318 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.318?

3 of the latest 49 opportunities under 93.318 are open or forecasted. The latest, Capacity Building for National Immunization Programs in the Eastern Mediterranean Region, was posted on August 31, 2026.

On GovTribe

See this program's full record

  • Every grant award and opportunity under it
  • Funding by recipient, agency and assistance type
  • Alerts for new opportunities
  • Ask GovTribe AI about this program