NAICS Code 541714: Research and Development in Biotechnology (except Nanobiotechnology)

National industry

SBA small business size standard: 1,000 employees

Definition

This U.S. industry comprises establishments primarily engaged in conducting biotechnology (except nanobiotechnology) research and experimental development. Biotechnology (except nanobiotechnology) research and experimental development involves the study of the use of microorganisms and cellular and biomolecular processes to develop or alter living or non-living materials.

This research and development in biotechnology (except nanobiotechnology) may result in development of new biotechnology (except nanobiotechnology) processes or in prototypes of new or genetically-altered products that may be reproduced, utilized, or implemented by various industries.

Code facts

Contract awards
275 In the last 12 months
Contract obligations
$1,484,685,277 In FY2025

NAICS codes and definitions come from the U.S. Census Bureau, size standards from the SBA and contract spending from SAM.gov/FPDS.

Business activities under NAICS 541714

  • Biotechnology research and development laboratories or service in botany
  • Biotechnology research and development laboratories or services
  • Biotechnology research and development laboratories or services in agriculture
  • Biotechnology research and development laboratories or services in bacteriology
  • Biotechnology research and development laboratories or services in biology
  • Biotechnology research and development laboratories or services in chemical sciences
  • Biotechnology research and development laboratories or services in entomology
  • Biotechnology research and development laboratories or services in environmental science
  • Biotechnology research and development laboratories or services in food science
  • Biotechnology research and development laboratories or services in genetics
  • Biotechnology research and development laboratories or services in health sciences
  • Biotechnology research and development laboratories or services in industrial research
  • Biotechnology research and development laboratories or services in the medical sciences
  • Biotechnology research and development laboratories or services in the physical sciences
  • Biotechnology research and development laboratories or services in the veterinary sciences
  • Cloning research and experimental development laboratories
  • DNA technologies (e.g., microarrays) research and experimental development laboratories
  • Nucleic acid chemistry research and experimental development laboratories
  • Protein engineering research and experimental development laboratories
  • Recombinant DNA research and experimental development laboratories

Contract obligations by fiscal year

Fiscal year Obligated
FY2027 To date $27,585,410
FY2026 $2,080,639,046
FY2025 $1,484,685,277
FY2024 $3,857,205,059
FY2023 $5,123,557,871

Top contractors by obligations

Rank Contractor Obligated, FY2026–FY2027 Share
1 Albert B. Sabin Vaccine Institute, Inc. (The) $261,929,856
2 Shionogi Inc. $156,103,536
3 Advanced Technology International $153,964,938
4 Amgen USA Inc. $125,985,024
5 L3 Technologies, Inc. $117,500,000
6 Kaleo, Inc. $99,842,892
7 Start2 Group, Inc. $89,057,280
8 Mapp Biopharmaceutical, Inc. $83,087,548
9 Basilea Pharmaceutica International Ltd, Allschwil $54,870,405
10 Ossium Health, Inc. $48,891,921

Top funding agencies by obligations

Rank Agency Obligated, FY2026–FY2027 Share
1 Department of Health and Human Services $1,679,429,048
2 Department of the Navy Department of Defense $193,860,221
3 Defense Health Agency Department of Defense $117,625,392
4 Department of Veterans Affairs $33,708,264
5 National Aeronautics and Space Administration $24,200,258
6 Defense Advanced Research Projects Agency Department of Defense $16,362,127
7 Defense Threat Reduction Agency Department of Defense $14,373,448
8 Air Force Department of Defense $13,537,976
9 Missile Defense Agency Department of Defense $4,698,674
10 Department of the Army Department of Defense $4,427,597

Contract obligations by state

Rank Place of performance Obligated, last 12 months Share
1 California $365,001,441
2 District of Columbia $264,471,318
3 Massachusetts $251,856,588
4 New Jersey $195,895,672
5 South Carolina $162,131,236
6 Virginia $152,684,547
7 Maryland $143,723,463
8 Utah $120,421,991
9 North Carolina $81,845,281
10 Texas $66,277,453
11 Pennsylvania $40,454,085
12 Ohio $37,929,793
13 Illinois $29,685,286
14 Florida $15,732,133
15 Georgia $15,552,619
16 Kentucky $15,102,045
17 New Mexico $15,001,843
18 New York $13,281,172
19 Washington $11,412,007
20 Delaware $10,557,079
21 Michigan $8,971,445
22 Connecticut $7,889,415
23 Oklahoma $7,372,860
24 Alabama $5,981,664
25 Iowa $4,096,468
26 Oregon $3,659,006
27 Arkansas $3,609,482
28 Colorado $3,561,607
29 Arizona $3,283,625
30 Missouri $2,818,679
31 Indiana $2,725,851
32 Montana $2,179,858
33 Nevada $2,015,239
34 Louisiana $1,992,917
35 Nebraska $1,838,383
36 Maine $1,351,883
37 Wisconsin $1,054,319
38 Minnesota $634,642
39 Mississippi $408,915
40 West Virginia $379,449
41 Hawaii $176,992
42 New Hampshire $102,908
43 Rhode Island $869
Show all 43

Shares are of everything obligated under NAICS 541714 in the last 12 months before deobligations, including work performed abroad or with no place of performance on record.

Contract opportunities

Notice Posted Due
Future Program: Laguna Special Notice · Defense Advanced Research Projects Agency
Service request for specimen embedding and sectioning. Special Notice · Shared Services Center
DNA Sequencing Service Pre-Solicitation · Office of Logisitics and Acquisition Operations (NIH)
FY27 FDA Broad Agency Announcement (BAA) for Advanced Research and Development of Regulatory Science Special Notice · FDA Office of Acquisition and Grant Services
Prototype phage hygiene spray bottles Solicitation · ACC Orlando
Traumatic Brain Injury and Psychological Health Research Program Public Request for Information Pre-Solicitation
RFI Alzheimer’s Research Program (AZRP) Public Pre-Solicitation
Quantitative Analysis of Longitudinal MR Images Pre-Solicitation · Office of Logisitics and Acquisition Operations (NIH)
AJ12--Development/Production - Kidney GEC-Specific AAV Vector Pre-Solicitation · Veterans Integrated Service Network 4 (VHA)
Alternative Protein Technologies for Military Field Feeding Pre-Solicitation · ACC Aberdeen Proving Ground
Pre-Clinical Models of Infectious Diseases Pre-Solicitation · National Institute of Allergy and Infectious Diseases (NIH)
HR001124C0315 DARPA justification and approval for other than full and open competition Limited / Sole Source Justification · Defense Advanced Research Projects Agency —
HR001124C0378 DARPA justification and approval for other than full and open competition Limited / Sole Source Justification · Defense Advanced Research Projects Agency —
Pre-Award Synopsis Texas Shield Special Notice · Defense Advanced Research Projects Agency
NSF X-Labs Initiative - From Sequence to Function Solicitation
DARPA Surgical Competition (DSC) Second Industry Day Special Notice · Defense Advanced Research Projects Agency
RFI Lupus Research Program (LRP) Public Pre-Solicitation
NOI - A Non-Invasive Prognostic Biomarker Solicitation · Office of Logisitics and Acquisition Operations (NIH)
J&A to extend Period or Performance for procurement of Inmazeb Limited / Sole Source Justification · Office of the Assistant Secretary for Preparedness and Response —
High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE) Solicitation · Defense Advanced Research Projects Agency
FY26 FDA Broad Agency Announcement (BAA) for Advanced Research and Development of Regulatory Science Award Notice · FDA Office of Acquisition and Grant Services —
Bridge Contract - Disease Surveillance and Research Support Limited / Sole Source Justification —
HR001126CE092 Biological Technologies Award Notice · Defense Advanced Research Projects Agency —
Pre-solicitation Notice: On-Ramp for the Department of Defense OMNIBUS IV Multiple-Award Contract Pre-Solicitation —
SURPASS Webinar and Proposers' Day Information Special Notice · National Institutes of Health
Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) Solicitation · National Institutes of Health
RFP - 2-PAM Autoinjectors for Project Bioshield (PBS) Award Notice · Office of the Assistant Secretary for Preparedness and Response —
Whole genome sequencing for investigation of age-related chronic disease in HANDLS participants Award Notice · Office of Logisitics and Acquisition Operations (NIH) · 75N98026R00166AN —
Advanced Development of OXOS X3, a Point-of-Care Diagnostic X-Ray Imaging System for Detection of Fracture and other Trauma Special Notice · Office of the Assistant Secretary for Preparedness and Response
Biobanking, Laboratory Analytics, and Associated Informatics Services for NIH Biorepositories Pre-Solicitation · National Institute on Drug Abuse (NIH) · 75N98026R00175SB
Biobanking, Laboratory Analytics, and Associated Informatics Services for NIH Biorepositories Pre-Solicitation · National Institute on Drug Abuse (NIH) · 75N98026R00175
HUBBLE DRAFT Program Announcement (PA) Pre-Solicitation · Defense Advanced Research Projects Agency
Request for Information (RFI) on Identifying Basic Research Challenges to Accelerate United States Biotechnology Leadership Special Notice · Department of Energy
SSJ-technical expertise and coordination support to the integrated consortium of laboratory networks Limited / Sole Source Justification —
precisionFDA cloud-based genomics platform Special Notice · Food and Drug Administration
Development of Light-Responsive Artificial Cells using Plant-Based Photoreceptor Systems Award Notice · US Army Corps of Engineers —
Broad agency announcement - biomedical research and diving equipment development Solicitation · Naval Sea Systems Command (Navy)
AN13--Miniaturized CO2 Sensor Prototype Development Award Notice · Veterans Integrated Service Network 4 (VHA) —
TECHNOLOGY LICENSING OPPORTUNITY: SignalGen Special Notice · Department of Energy
Sole Source Bioconscientia Pre-Solicitation · Engineer Research and Development Center (USACE)
Lumicks C-Trap® Correlative Optical Tweezers - Fluorescence Microscope System Solicitation · Office of Logisitics and Acquisition Operations (NIH)
NOTICE OF INTENT TO SOLE SOURCE for the Development of a Handheld Device for Rapid Assessment of Burn Sepsis Risk Special Notice
Firefox Solicitation · Defense Advanced Research Projects Agency
ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening Solicitation · National Institutes of Health
UNifying Imaging with QUantum Entanglement (UNIQUE) Innovative Solutions Opening (ISO) Solicitation · National Institutes of Health
UNifying Imaging with QUantum Entanglement (UNIQUE) Proposers' Day Special Notice · National Institutes of Health
Notice of Intent to Sole Source - Metabolomic Analysis Special Notice · Agricultural Research Service
Statistical and Data Coordinating Center (SDCC) for Clinical Research in Infectious Diseases Pre-Solicitation · National Institute of Allergy and Infectious Diseases (NIH)
ARPA-H Emerging Health Innovators (EHI) Initiative Solicitation · National Institutes of Health
Whole genome sequencing for investigation of age-related chronic disease in HANDLS participants Solicitation · Office of Logisitics and Acquisition Operations (NIH) · 75N98026R00166
Show 40 more

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Size standard history

Federal Register rules that named this code

Final rule Published Effective
Small Business Size Standards; Adoption of 2017 North American Industry Classification System for Size Standards 82 FR 44886 · 3245-AG84

From the NAICS codes each rule's amendments to 13 CFR 121.201 name. Rules that print their size standard tables as images aren't listed.

Quick answers

What is NAICS 541714?

NAICS 541714 is Research and Development in Biotechnology (except Nanobiotechnology), a national industry in NAICS 54, Professional, Scientific, and Technical Services.

What is the NAICS code for cloning research and experimental development laboratories?

The NAICS code for cloning research and experimental development laboratories is 541714, Research and Development in Biotechnology (except Nanobiotechnology).

What is the NAICS code for biotechnology research and development laboratories or services?

The NAICS code for biotechnology research and development laboratories or services is 541714, Research and Development in Biotechnology (except Nanobiotechnology).

What is the NAICS code for recombinant DNA research and experimental development laboratories?

The NAICS code for recombinant DNA research and experimental development laboratories is 541714, Research and Development in Biotechnology (except Nanobiotechnology).

When did the size standard for NAICS 541714 last change?

The most recent Federal Register rule on record that names NAICS 541714 in the SBA's size standards is "Small Business Size Standards; Adoption of 2017 North American Industry Classification System for Size Standards" (82 FR 44886), published Sep 27, 2017 and effective Oct 1, 2017.

How much do federal agencies spend under NAICS 541714?

Federal contracts under NAICS 541714 obligated $1,484,685,277 in fiscal year 2025 and $12,573,672,663 in fiscal years 2023 through 2027.

Who are the largest contractors under NAICS 541714?

The contractors with the most obligated under NAICS 541714 in fiscal years 2026 and 2027 are Albert B. Sabin Vaccine Institute, Inc. (The) ($261,929,856); Shionogi Inc. ($156,103,536); and Advanced Technology International ($153,964,938).

Which agencies buy the most under NAICS 541714?

The agencies that obligated the most under NAICS 541714 in fiscal years 2026 and 2027 are Department of Health and Human Services ($1,679,429,048), Department of the Navy ($193,860,221) and Defense Health Agency ($117,625,392).

Which PSC codes are used with NAICS 541714?

The PSC codes with the most obligated under NAICS 541714 in fiscal years 2026 and 2027 are AN13 Health R&D Services; Health Care Services; Experimental Development, 6505 Drugs and Biologicals and AN42 Health R&D Services; Health Care – Other; Applied Research.

Where is the work under NAICS 541714 performed?

By place of performance, the states with the most contract obligations under NAICS 541714 over the last 12 months are California ($365,001,441), the District of Columbia ($264,471,318) and Massachusetts ($251,856,588).

What is the latest contract opportunity under NAICS 541714?

The latest contract opportunity under NAICS 541714 is Future Program: Laguna, special notice from Defense Advanced Research Projects Agency, posted November 5, 2026.

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