NAICS Code 325412: Pharmaceutical Preparation Manufacturing

National industry

SBA small business size standard: 1,300 employees

Definition

This U.S. industry comprises establishments primarily engaged in manufacturing in-vivo diagnostic substances and pharmaceutical preparations (except biological) intended for internal and external consumption in dose forms, such as ampoules, tablets, capsules, vials, ointments, powders, solutions, and suspensions.

Code facts

Contract awards
12,558 In the last 12 months
Contract obligations
$13,086,572,033 In FY2025

NAICS codes and definitions come from the U.S. Census Bureau, size standards from the SBA and contract spending from SAM.gov/FPDS.

Business activities under NAICS 325412

  • Adrenal medicinal preparations manufacturing
  • Analgesic preparations manufacturing
  • Anesthetic preparations manufacturing
  • Angiourographic diagnostic preparations manufacturing
  • Antacid preparations manufacturing
  • Anthelmintic preparations manufacturing
  • Antibacterial preparations manufacturing
  • Antibiotic preparations manufacturing
  • Antidepressant preparations manufacturing
  • Antihistamine preparations manufacturing
  • Antineoplastic preparations manufacturing
  • Antipyretic preparations manufacturing
  • Antiseptic preparations manufacturing
  • Antispasmodic preparations manufacturing
  • Astringent preparations manufacturing
  • Barbiturate preparations manufacturing
  • Barium in-vivo diagnostic substances manufacturing
  • Belladonna preparations manufacturing
  • Birth control pills manufacturing
  • Botanical extract preparations (except in-vitro diagnostics) manufacturing
  • Cardiac preparations manufacturing
  • Cathartic preparations manufacturing
  • Central nervous system stimulant preparations manufacturing
  • Coagulation in-vivo diagnostic substances manufacturing
  • Cold remedies manufacturing
  • Contraceptive preparations manufacturing
  • Contrast media in-vivo diagnostic substances (e.g., iodine, barium) manufacturing
  • Cough drops, medicated, manufacturing
  • Cough medicines manufacturing
  • Cyclopropane medicinal preparations manufacturing
  • Dermatological preparations manufacturing
  • Diagnostic biological preparations (except in-vitro) manufacturing
  • Digestive system preparations manufacturing
  • Digitalis medicinal preparations manufacturing
  • Diuretic preparations manufacturing
  • Effervescent salts manufacturing
  • Electrolyte in-vivo diagnostic substances manufacturing
  • Eye and ear preparations manufacturing
  • Fever remedy preparations manufacturing
  • Glandular medicinal preparations manufacturing
  • Hematology in-vivo diagnostic substances manufacturing
  • Hormone preparations (except in-vitro diagnostics) manufacturing
  • Insulin preparations manufacturing
  • Intravenous (IV) solution preparations manufacturing
  • In-vivo diagnostic substances manufacturing
  • Iodinated in-vivo diagnostic substances manufacturing
  • Laxative preparations manufacturing
  • Lip balms manufacturing
  • Metabolite in-vivo diagnostic substances manufacturing
  • Mouthwashes, medicated, manufacturing
  • Muscle relaxant preparations manufacturing
  • Nonprescription drug preparations manufacturing
  • Nuclear medicine (e.g., radioactive isotopes) preparations manufacturing
  • Oral contraceptive preparations manufacturing
  • Patent medicine preparations manufacturing
  • Penicillin preparations manufacturing
  • Pharmaceutical preparations (e.g., capsules, liniments, ointments, tablets) manufacturing
  • Pituitary gland preparations manufacturing
  • Radioactive in-vivo diagnostic substances manufacturing
  • Sedative preparations manufacturing
  • Sodium chloride pharmaceutical preparations manufacturing
  • Sodium salicylate preparations manufacturing
  • Suppositories manufacturing
  • Technetium medicinal preparations manufacturing
  • Thyroid preparations manufacturing
  • Tincture of iodine preparations manufacturing
  • Tranquilizer preparations manufacturing
  • Vermifuge preparations manufacturing
  • Veterinary medicinal preparations manufacturing
  • Vitamin preparations manufacturing
  • Water (i.e., drinking) decontamination or purification tablets manufacturing
  • Zinc oxide medicinal preparations manufacturing
Show all 72

Contract obligations by fiscal year

Fiscal year Obligated
FY2027 To date $26,588,805
FY2026 $12,094,709,665
FY2025 $13,086,572,033
FY2024 $10,085,282,215
FY2023 $12,774,835,827

Top contractors by obligations

Rank Contractor Obligated, FY2026–FY2027 Share
1 Mckesson Corporation $11,174,004,123
2 Emergent Biosolutions Canada Inc. $118,251,472
3 Phlow Corp. $105,274,410
4 Exelan Pharmaceuticals Inc. $92,765,697
5 DLA Troop Support $68,310,123
6 Fresenius Kabi, LLC $57,687,062
7 Mckesson Specialty Distribution LLC $51,046,412
8 Partner Therapeutics, Inc. $50,234,675
9 Novartis Pharmaceuticals Corporation $43,346,165
10 Teva Pharmaceuticals Usa, Inc. $34,980,236

Top funding agencies by obligations

Rank Agency Obligated, FY2026–FY2027 Share
1 Department of Veterans Affairs $11,148,533,421
2 Department of Health and Human Services $662,431,951
3 Department of Justice $214,639,689
4 Defense Logistics Agency Department of Defense $51,773,069
5 Defense Health Agency Department of Defense $20,027,816
6 Department of Homeland Security $17,889,326
7 Department of Agriculture $4,144,676
8 Department of State $701,372
9 Department of the Army Department of Defense $471,215
10 Peace Corps $391,659

Contract obligations by state

Rank Place of performance Obligated, last 12 months Share
1 Texas $11,092,041,583
2 Tennessee $88,477,265
3 Virginia $87,964,046
4 Pennsylvania $84,094,827
5 Florida $79,937,632
6 Illinois $76,194,873
7 Massachusetts $74,282,006
8 New Jersey $67,195,270
9 Oklahoma $43,122,645
10 Georgia $40,658,791
11 North Carolina $35,836,477
12 New York $29,164,522
13 California $12,988,525
14 Ohio $11,931,874
15 Missouri $9,584,982
16 Connecticut $4,729,573
17 Kentucky $4,127,007
18 Iowa $3,197,356
19 Kansas $2,695,100
20 Maryland $2,396,416
21 Louisiana $1,732,694
22 North Dakota $1,165,212
23 Minnesota $1,121,773
24 Hawaii $964,132
25 South Carolina $703,502
26 Michigan $616,415
27 Washington $615,179
28 Nebraska $560,898
29 West Virginia $541,872
30 Indiana $425,330
31 Rhode Island $281,506
32 Alabama $220,191
33 South Dakota $211,629
34 New Hampshire $170,436
35 Nevada $147,988
36 Delaware $120,555
37 Guam $99,196
38 Montana $59,846
39 Colorado $49,275
40 Maine $18,175
41 District of Columbia $4,526
Show all 41

Shares are of everything obligated under NAICS 325412 in the last 12 months before deobligations, including work performed abroad or with no place of performance on record.

Contract opportunities

Notice Posted Due
Sirturo (Bedaquiline) tablets for the NIH (Notice of Intent to sole source) Pre-Solicitation · NIH Clinical Center
6505--FY27 F18 Florebetapir Award Notice · Veterans Integrated Service Network 8 (VHA) —
SOURCES SOUGHT Charleston CMOP CARBOXYMETHYLCELLULOSE NA 0.25% OPH SOLN 15ML Pre-Solicitation · Veterans Integrated Service Network 15 (VHA)
6505--Denali Therapeutics, Inc. 12/01/2026 - 11/30/2031 Award Notice · Veterans Integrated Service Network 12 (VHA) —
6505--MVAHCS FDG Radiopharmaceutical Sources Sought Pre-Solicitation · Veterans Integrated Service Network 23 (VHA)
6505--Sources Sought VISN2 DOWNSTATE GENERAL RADIOPHARMACEUTICALS Pre-Solicitation · Veterans Integrated Service Network 2 (VHA)
6505--General Radioisotopes (Diagnostic & Therapeutic) Pre-Solicitation · Veterans Integrated Service Network 19 (VHA)
Fentanyl Pre-Solicitation · Medical Supply Chain (DLA) —
Medical Gas Cylinders, USP, Type I-DOT 3AA Steel Pre-Solicitation · Medical Supply Chain (DLA)
6505--Radiopharmaceuticals Base Plus Four Option Years VA San Diego Healthcare System Pre-Solicitation · Veterans Integrated Service Network 22 (VHA)
6505--Request for Information (RFI) - Specialty Pharmacy List - Pharmaceutical Prime Vendor (PPV) 2028 Pre-Solicitation · Department of Veterans Affairs
6505--FY27 Lenalidomide BPA Pre-Solicitation · Veterans Integrated Service Network 22 (VHA)
6505--Latanoprost Ophthalmic Solution (VA-27-00006027) Solicitation · National Acquisition Center (VA) · 36E79727R0039
6505--Lab Supplies - Radiopharm | Philadelphia Award Notice · Veterans Integrated Service Network 4 (VHA) —
6505--Ramipril Capsules RFP Pre-Solicitation · National Acquisition Center (VA)
6505--Emergency Pluvicto and Lutathera Award Notice · Veterans Integrated Service Network 22 (VHA) —
WBAMC Microspheres Award Notice · Defense Health Agency —
6505--INTENT TO SOLE SOURCE Radiopharm - Lutathera & Pluvicto - Lebanon VAMC Special Notice · Veterans Integrated Service Network 4 (VHA)
Atropine Auto-Injector Pre-Solicitation · Medical Supply Chain (DLA)
6505--VA Long Beach Pylarify Special Notice · Veterans Integrated Service Network 22 (VHA)
6505--Alembic Therapeutics, LLC 65IB 36F79727D0008 Effective 11-1-2026 through 10-31- 2031 Award Notice · Veterans Integrated Service Network 12 (VHA) —
6505--Dutasteride Capsules - AvKARE LLC Award Notice · National Acquisition Center (VA) —
6505--766-27-1-400-0021 -Charleston CMOP CALCIUM 500MG/VIT D 500UNIT CHEW TAB 90CT -(VA-27-00014312) Pre-Solicitation · Veterans Integrated Service Network 15 (VHA)
Pet radiopharmaceuticals Award Notice · Veterans Integrated Service Network 7 (VHA) —
F18 pet radiopharmaceuticals Award Notice · Veterans Integrated Service Network 7 (VHA) —
6505--Sources Sought Notice - Ga68 Dotatate (NETSPOT) Special Notice · Veterans Integrated Service Network 17 (VHA)
6505--Sacubitril/Valsartan Tablets (VA-27-00014055) Pre-Solicitation · National Acquisition Center (VA)
Sanofi 20262027 Flu Vaccines Limited / Sole Source Justification · Office of Acquisition Management —
19AQMM26F1521 - Sole Source Justification Under Federal Supply Schedule: 20262027 Flu vaccines Limited / Sole Source Justification · Office of Acquisition Management —
6505--FY27 Low Energy General Radiopharmaceuticals 36C25027Q0052 Pre-Solicitation · Veterans Integrated Service Network 10 (VHA)
6505--Imatinib Tablets Solicitation · National Acquisition Center (VA) · 36E79726R0036
6505--Sodium Bicarbonate Injection Vial Restricted to Made in America Pre-Solicitation · National Acquisition Center (VA)
6505--Department of Veterans Affairs Pharmaceutical Industry Day Special Notice · Veterans Integrated Service Network 12 (VHA)
Lidocaine 5% patches-request for information Pre-Solicitation · Veterans Integrated Service Network 15 (VHA)
Notice of Intent to Sole Source – CARDINAL HEALTH 414, LLC– radiopharmaceuticals Pre-Solicitation · Office of Logisitics and Acquisition Operations (NIH)
6505--Lab Supplies - Radiopharm Philadelphia VA Medical Center Solicitation · Veterans Integrated Service Network 4 (VHA) · 36C24427Q0018
6505--Lab Supplies - Radiopharm Philadelphia VA Medical Center Pre-Solicitation · Veterans Integrated Service Network 4 (VHA) · 36C24427Q0018
Department of War Pharmacy Uniform Formulary Blanket Purchase Agreement / Uniform Formulary Additional Discount Program Solicitation · Defense Health Agency
Inhaled Nitric Oxide Pre-Solicitation · Defense Health Agency
IHC Reagents and Supplies Award Notice · Defense Health Agency —
6505--Imatinib Tablets Pre-Solicitation · National Acquisition Center (VA) · 36E79726R0036
SNS Pharmaceutical Logistic Replenishment Requirement Award Notice · Office of the Assistant Secretary for Preparedness and Response —
6505--Radiopharmaceuticals Award Notice · Veterans Integrated Service Network 16 (VHA) —
6505--Notice of Intent to Sole-Source for Pluvicto (Lutetium Lu 177 Vipivotide Tetraxetan) and Lutathera (Lutetium Lu 177 Dotatate) for Buffalo VA Medical Center Special Notice · Veterans Integrated Service Network 2 (VHA)
6505--Latanoprost Ophthalmic Solution (VA-27-00006027) Pre-Solicitation · National Acquisition Center (VA) · 36E79727R0039
Show 35 more

Latest 45 of 16,567 listed here. See the rest on GovTribe.

Size standard history

Federal Register rules that named this code

From the NAICS codes each rule's amendments to 13 CFR 121.201 name. Rules that print their size standard tables as images aren't listed.

Quick answers

What is NAICS 325412?

NAICS 325412 is Pharmaceutical Preparation Manufacturing, a national industry in NAICS 31-33, Manufacturing.

What is the NAICS code for lip balms manufacturing?

The NAICS code for lip balms manufacturing is 325412, Pharmaceutical Preparation Manufacturing.

What is the NAICS code for cold remedies manufacturing?

The NAICS code for cold remedies manufacturing is 325412, Pharmaceutical Preparation Manufacturing.

What is the NAICS code for suppositories manufacturing?

The NAICS code for suppositories manufacturing is 325412, Pharmaceutical Preparation Manufacturing.

When did the size standard for NAICS 325412 last change?

The most recent Federal Register rule on record that names NAICS 325412 in the SBA's size standards is "Small Business Size Standards: Manufacturing and Industries With Employee-Based Size Standards in Other Sectors Except Wholesale Trade and Retail Trade" (88 FR 9970), published Feb 15, 2023 and effective Mar 17, 2023.

How much do federal agencies spend under NAICS 325412?

Federal contracts under NAICS 325412 obligated $13,086,572,033 in fiscal year 2025 and $48,067,988,546 in fiscal years 2023 through 2027.

Who are the largest contractors under NAICS 325412?

The contractors with the most obligated under NAICS 325412 in fiscal years 2026 and 2027 are Mckesson Corporation ($11,174,004,123), Emergent Biosolutions Canada Inc. ($118,251,472) and Phlow Corp. ($105,274,410).

Which agencies buy the most under NAICS 325412?

The agencies that obligated the most under NAICS 325412 in fiscal years 2026 and 2027 are Department of Veterans Affairs ($11,148,533,421), Department of Health and Human Services ($662,431,951) and Department of Justice ($214,639,689).

Which PSC codes are used with NAICS 325412?

The PSC codes with the most obligated under NAICS 325412 in fiscal years 2026 and 2027 are 6505 Drugs and Biologicals; AN17 R&D – Medical: Biomedical (Commercialized); and 6515 Medical and Surgical Instruments, Equipment, and Supplies.

Where is the work under NAICS 325412 performed?

By place of performance, the states with the most contract obligations under NAICS 325412 over the last 12 months are Texas ($11,092,041,583), Tennessee ($88,477,265) and Virginia ($87,964,046).

What is the latest contract opportunity under NAICS 325412?

The latest contract opportunity under NAICS 325412 is Sirturo (Bedaquiline) tablets for the NIH (Notice of Intent to sole source), pre-solicitation from NIH Clinical Center, posted November 6, 2026.

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