Exhibit 57b - Cal Yr 2025 City of Miami YTD as of Apr Stats by Ther Class _ Brand - Healthcare Spend and Trend - Pharmacy - Paid.xlsx

XLSX spreadsheet 457 KB Posted

Attached to
RFP No. 2130386 - Employee Health Benefits Plan
Solicitation number
RFP No. 2130386
Issued by
Florida

About this file

The document is a pharmacy spend and trend analysis report for the City of Miami's employee health benefits plan for calendar year 2025, covering January through April. The report provides detailed pharmaceutical utilization and cost metrics across various therapeutic classes, including breakdowns by generic, preferred brand, and non-preferred brand medications. The analysis tracks 16,229 total prescriptions with a total ingredient cost of $4,691,417, representing a 8.7% increase from the base period. Key pharmacy metrics include an average of 2,101 employees, 4,294 members, and an ingredient cost per member per month (PMPM) of $273.12, up 12.2% from the previous period.

The report reveals significant shifts in prescription patterns, with retail scripts increasing by 10.4% and mail order scripts declining by 12.1%. Specialty medications continue to represent a substantial portion of total spend, accounting for 52% of employer-paid costs. Generic medication utilization remains high at 93.8%, and the formulary brand compliance rate improved to 90.8%. The analysis shows increases in both plan spend (32.3% increase) and employer-paid amounts (33.9% increase), with a modest 11.1% increase in member-paid contributions. This comprehensive pharmacy spend report appears to be supporting a potential upcoming employee health benefits plan procurement, potentially related to the referenced RFP No. 2130386 for Employee Health Benefits Plan in Florida.

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CP_824

EXHIBIT 57b
Pharmacy Statistics by Therapeutic Class
BaseCurrentBase - Current % Change
Standard Therapeutic CategoryTherapeutic ClassNumber of PrescriptionsNumber of ClaimantsDays SupplyIngredient CostEmployer Paid Per PrescriptionIngredient Cost Per PrescriptionEmployer Paid Per ClaimantCost ShareEmployer PaidPlan AmountNumber of PrescriptionsNumber of ClaimantsDays SupplyIngredient CostEmployer Paid Per PrescriptionIngredient Cost Per PrescriptionEmployer Paid Per ClaimantCost ShareEmployer PaidPlan AmountDays SupplyMember PaidEmployer PaidPlan Amount
Diabetic TherapyAntihyperglycemic - Incretin Mimetics Combina38313312,440$443,265$1,129$1,157$3,252$10,975$432,515$443,49063821720,588$742,720$1,136$1,164$3,340$18,232$724,844$743,07665%66%68%68%
Diabetic TherapyAntihypergly,incretin Mimetic(Glp-1 Recep.Agonist)28311510,673$330,371$1,121$1,167$2,758$13,323$317,194$330,51834813111,622$372,832$1,027$1,071$2,728$15,625$357,387$373,0129%17%13%13%
Diabetic TherapyAntihyperglycemc-Sod/Gluc Cotransport2(Sglt2)inhib133716,870$125,072$897$940$1,681$5,760$119,367$125,127144747,326$134,462$891$934$1,733$6,240$128,278$134,5187%8%7%8%
Diabetic TherapyInsulins105535,367$47,580$399$453$791$5,695$41,916$47,611131536,363$66,200$455$505$1,125$6,595$59,649$66,24419%16%42%39%
Diabetic TherapyAntihyperglycemic-Sglt2 Inhibitor & Biguanide Comb24141,500$22,902$902$954$1,547$1,250$21,659$22,90926171,575$25,063$913$964$1,397$1,325$23,745$25,0705%6%10%9%
Diabetic TherapyAntihyperglycemic, Dpp-4 Inhibitors20121,344$23,398$1,104$1,170$1,840$1,320$22,083$23,40320101,010$10,307$462$515$923$1,080$9,235$10,315-25%-18%-58%-56%
Diabetic TherapyAntihyperglycemic,dpp-4 Inhibitor & Biguanide Comb1711930$14,303$785$841$1,214$960$13,349$14,309189960$8,444$414$469$828$1,000$7,450$8,4503%4%-44%-41%
Diabetic TherapyHyperglycemics2260$876$411$438$411$55$822$8774390$4,265$1,017$1,066$1,356$200$4,067$4,26750%264%395%387%
Diabetic TherapyAntihypergly-Sglt-2 Inhib,dpp-4 Inhib,biguanide2260$1,158$555$579$555$50$1,109$1,15942120$2,370$568$593$1,136$100$2,272$2,372100%100%105%105%
Diabetic TherapyAntihyperglycemic,biguanide Type(Non-Sulfonylurea)31618519,770$2,643$7$8$12$601$2,133$2,73432419419,627$2,156$5$7$9$556$1,693$2,249-1%-8%-21%-18%
Diabetic TherapyAntihyperglycemic, Insulin-Release Stimulant Type68454,440$976$11$14$17$219$775$99480494,620$1,034$9$13$14$366$694$1,0604%67%-10%7%
Diabetic TherapyAntihyperglycemic,insulin-Rel Stim.& Biguanide Cmb107720$618$58$62$82$45$575$62055450$381$76$76$76$0$381$381-38%-100%-34%-39%
Diabetic TherapyAntihyperglycemic, Insulin-Response Enhancer (N-S)179870$354$14$21$27$119$242$361137750$366$21$28$38$102$269$371-14%-15%11%3%
Diabetic TherapyAntihyperglycemic, Sglt-2 & Dpp-4 Inhibitor Comb.1190$1,652$1,577$1,652$1,577$75$1,577$1,652000$0$0$0$0$0$0$0-100%-100%-100%-100%
Diabetic TherapySubtotal1,38143865,134$1,015,167$706$735$2,227$40,448$975,317$1,015,7651,75554075,101$1,370,599$752$781$2,444$51,420$1,319,963$1,371,38415%27%35%35%
MiscellaneousMonoclonal Antibody-Human Interleukin 12/23 Inhib135532$367,211$28,185$28,247$73,282$800$366,411$367,21185350$249,879$31,165$31,235$49,864$560$249,319$249,879-34%-30%-32%-32%
MiscellaneousIl-23 Receptor Antagonist, Monoclonal Antibod000$0$0$0$0$0$0$063336$144,374$23,982$24,062$47,965$480$143,894$144,3740%0%0%0%
MiscellaneousAgents To Treat Multiple Sclerosis105526$114,351$11,400$11,435$22,800$350$114,001$114,35195496$106,835$11,833$11,871$21,300$335$106,500$106,835-6%-4%-7%-7%
MiscellaneousInterleukin-4(Il-4) Receptor Alpha Antagonist, Mab74588$82,471$11,702$11,782$20,478$560$81,911$82,471126616$91,053$7,531$7,588$15,063$680$90,376$91,0565%21%10%10%
MiscellaneousAmyotrophic Lateral Sclerosis Agents000$0$0$0$0$0$0$061292$66,167$10,988$11,028$65,927$240$65,927$66,1670%0%0%0%
MiscellaneousAnti-Inflammatory Tumor Necrosis Factor Inhibitor42182$40,771$10,083$10,193$20,165$440$40,331$40,77162224$37,507$6,184$6,251$18,553$400$37,107$37,50723%-9%-8%-8%
MiscellaneousInterleukin-31(Il-31)receptor Alpha Antagonist,mab000$0$0$0$0$0$0$041112$35,519$8,830$8,880$35,319$200$35,319$35,5190%0%0%0%
MiscellaneousBone Formation Stim. Agents - Parathyroid Hormone3184$13,348$4,396$4,449$13,188$160$13,188$13,34821168$27,837$13,799$13,919$27,597$240$27,597$27,837100%50%109%109%
MiscellaneousImmunosuppressives45112,305$31,126$680$692$2,782$525$30,605$31,13038122,284$22,371$581$589$1,841$285$22,094$22,379-1%-46%-28%-28%
MiscellaneousIrritable Bowel Agents,guanylate Cylase-C Agonist2315930$15,680$635$682$974$1,080$14,612$15,6922113870$15,461$689$736$1,113$1,000$14,471$15,471-6%-7%-1%-1%
MiscellaneousThymic Stromal Lymphopoietin (Tslp) Inhibitor000$0$0$0$0$0$0$01184$13,330$13,250$13,330$13,250$80$13,250$13,3300%0%0%0%
MiscellaneousDrugs To Treat Impotency2041078,228$12,771$52$63$99$2,246$10,619$12,86523513110,154$8,114$25$35$45$2,309$5,906$8,21523%3%-44%-36%
MiscellaneousCalcimimetic,parathyroid Calcium Enhancer64300$5,458$900$910$1,350$60$5,401$5,46153330$5,602$1,114$1,120$1,857$30$5,572$5,60210%-50%3%3%
MiscellaneousPseudobulbar Affect (Pba) Agents, Nmda Antagonists000$0$0$0$0$0$0$01190$4,396$4,276$4,396$4,276$120$4,276$4,3960%0%0%0%
MiscellaneousTopical Antibiotics/Antiinflammatory,steroidal000$0$0$0$0$0$0$03190$2,732$851$911$2,554$180$2,554$2,7340%0%0%0%
MiscellaneousBenign Prostatic Hypertrophy/Micturition Agents108626,815$2,333$18$22$32$387$1,977$2,364121737,595$2,200$16$18$26$334$1,898$2,23111%-14%-4%-6%
MiscellaneousMenopausal Symptoms Suppressant - Nk3 Receptor44180$3,087$697$772$697$300$2,789$3,0892160$1,094$487$547$975$120$975$1,095-67%-60%-65%-65%
MiscellaneousChronic Inflam. Colon Dx, 5-A-Salicylat,rectal Tx22120$868$427$434$427$15$854$86943180$908$216$227$288$45$865$91050%200%1%5%
MiscellaneousNarcotic Withdrawal Therapy Agents82240$2,976$358$372$1,431$120$2,861$2,9814193$867$202$217$810$60$810$870-61%-50%-72%-71%
MiscellaneousDental Aids And Preparations64591,270$636$4$10$4$451$226$67880641,519$592$1$7$1$564$75$63920%25%-67%-6%
MiscellaneousAlzheimer's Therapy, Nmda Receptor Antagonists84330$128$7$16$15$73$60$13275331$616$78$88$110$71$548$6190%-3%821%368%
MiscellaneousRectal Preparations6683$498$69$83$69$90$412$50298147$598$52$66$59$133$470$60377%48%14%20%
MiscellaneousAlzheimer's Thx,nmda Recept Antag & Cholines Inhib000$0$0$0$0$0$0$03121$419$80$140$241$180$241$4210%0%0%0%
MiscellaneousBone Resorption Inhibitors29201,952$395$13$14$19$24$377$40125171,868$328$12$13$18$18$312$331-4%-25%-17%-18%
MiscellaneousGeneral Inhalation Agents99198$117$2$13$2$103$21$1231414336$211$5$15$5$154$66$21970%50%220%78%
MiscellaneousFluoride Preparations2619984$377$1$14$2$353$38$3911111348$140$0$13$0$146$0$146-65%-59%-100%-63%
MiscellaneousAppetite Stim. For Anorexia,cachexia,wasting Synd.3384$121$26$40$26$45$78$12362150$132$8$22$23$90$45$13579%100%-42%10%
MiscellaneousUrinary Ph Modifiers22120$332$159$166$159$15$317$3321190$118$118$118$118$0$118$118-25%-100%-63%-64%
MiscellaneousAntidiarrheal Microorganisms Agents3290$130$0$43$0$132$0$1321130$43$0$43$0$44$0$44-67%-67%0%-67%
MiscellaneousPeriodontal Collagenase Inhibitors000$0$0$0$0$0$0$02160$29$0$14$1$29$1$300%0%0%0%
MiscellaneousHypoactive Sexual Desire Disorder (Hsdd) Tx Agents21180$4,488$2,124$2,244$4,248$240$4,248$4,488000$0$0$0$0$0$0$0-100%-100%-100%-100%
MiscellaneousNicotinic Recept.Partial Agonist, Alpha4beta2 Spec2160$1,293$587$647$1,175$120$1,175$1,295000$0$0$0$0$0$0$0-100%-100%-100%-100%
MiscellaneousInterleukin-6 (Il-6) Receptor Inhibitors1184$7,401$7,321$7,401$7,321$80$7,321$7,401000$0$0$0$0$0$0$0-100%-100%-100%-100%
MiscellaneousInterleukin-13 (Il-13) Inhibitors, Mab2156$7,882$3,901$3,941$7,802$80$7,802$7,882000$0$0$0$0$0$0$0-100%-100%-100%-100%
MiscellaneousSubtotal59432126,521$716,252$1,191$1,206$2,204$8,849$707,635$716,48464734029,324$839,472$1,284$1,297$2,443$9,127$830,585$839,71211%3%17%17%
AntineoplasticsAntineoplastic Systemic Enzyme Inhibitors93262$154,037$17,073$17,115$51,220$380$153,660$154,040236658$391,997$17,003$17,043$65,178$940$391,068$392,008151%147%155%154%
AntineoplasticsAntineoplastic-B Cell Lymphoma-2(Bcl-2) Inhibitors72200$48,435$6,880$6,919$24,080$280$48,159$48,4393184$34,585$11,489$11,528$34,467$120$34,467$34,587-58%-57%-28%-29%
AntineoplasticsAntineoplastic Immunomodulator Agents1128$15,808$15,793$15,808$15,793$15$15,793$15,8082156$31,617$15,793$15,808$31,587$30$31,587$31,617100%100%100%100%
AntineoplasticsAlkylating Agents53270$168$25$34$42$45$125$170104368$5,940$582$594$1,456$120$5,823$5,94336%167%4,564%3,399%
AntineoplasticsAntineoplastic - Aromatase Inhibitors32161,424$4,270$131$133$261$106$4,180$4,28534201,468$3,991$116$117$197$75$3,931$4,0063%-29%-6%-7%
AntineoplasticsAntineoplastic Lhrh(Gnrh) Agonist,pituitary Suppr.000$0$0$0$0$0$0$02244$1,073$522$536$522$30$1,043$1,0730%0%0%0%
AntineoplasticsSelective Estrogen Receptor Modulators (Serm)136630$964$75$74$162$0$970$97053450$547$109$109$182$0$547$547-29%0%-44%-44%
AntineoplasticsAntimetabolites189823$4,268$228$237$455$178$4,095$4,273139797$311$19$24$28$63$251$314-3%-64%-94%-93%
AntineoplasticsTopical Antineoplastic & Premalignant Lesion Agnts2260$158$65$79$65$30$130$1603290$171$42$57$63$45$126$17150%50%-3%7%
AntineoplasticsSteroid Antineoplastics1130$14$0$14$0$14$0$14000$0$0$0$0$0$0$0-100%-100%0%-100%
AntineoplasticsAntineoplastic - Hedgehog Pathway Inhibitor2156$26,935$13,428$13,467$26,856$80$26,856$26,936000$0$0$0$0$0$0$0-100%-100%-100%-100%
AntineoplasticsSubtotal90433,783$255,057$2,822$2,834$5,906$1,128$253,969$255,09695454,015$470,231$4,935$4,950$10,419$1,423$468,843$470,2666%26%85%84%
AntiviralsArv Cmb-Nrti,n(T)rti, Integrase Inhibitor35121,110$148,615$4,206$4,246$12,266$1,440$147,196$148,63643131,350$202,178$4,661$4,702$15,419$1,760$200,441$202,20122%22%36%36%
AntiviralsAntivirals, Hiv-Spec, Nucleoside-Nucleotide Analog30151,320$64,191$2,137$2,140$4,273$110$64,096$64,20631151,302$76,980$2,484$2,483$5,133$0$76,995$76,995-1%-100%20%20%
AntiviralsAntiretroviral-Integrase Inhibitor And Nnrti Comb.53298$42,575$8,435$8,515$14,058$400$42,175$42,57553360$45,793$9,055$9,159$15,091$520$45,273$45,79321%30%7%8%
AntiviralsArv Comb-Nrtis & Integrase Inhibitor82240$30,202$3,736$3,775$14,944$320$29,887$30,20763300$36,060$5,957$6,010$11,914$320$35,743$36,06325%0%20%19%
AntiviralsAntiretroviral-Integrase Inhibitor And Nrti Comb.82300$29,987$3,704$3,748$14,816$360$29,631$29,99163240$26,509$4,372$4,418$8,744$280$26,232$26,512-20%-22%-11%-12%
AntiviralsAntiretroviral-Nucleoside,nucleotide,protease Inh.1130$4,752$4,712$4,752$4,712$40$4,712$4,75221120$19,290$9,585$9,645$19,171$120$19,171$19,291300%200%307%306%
AntiviralsArtv Cmb Nucleoside,nucleotide,&non-Nucleoside Rti22180$22,135$10,947$11,067$10,947$240$21,895$22,1353190$12,432$4,085$4,144$12,254$180$12,254$12,434-50%-25%-44%-44%
AntiviralsAntivirals,hiv-1 Integrase Strand Transfer Inhibtr54210$14,618$2,900$2,924$3,625$120$14,500$14,62032125$8,804$2,921$2,935$4,382$40$8,764$8,804-40%-67%-40%-40%
AntiviralsHepatitis B Treatment Agents22180$5,897$2,908$2,948$2,908$80$5,817$5,89722180$5,845$2,882$2,922$2,882$80$5,765$5,8450%0%-1%-1%
AntiviralsAntiviral - Main Protease (Mpro) Inhibitor161680$8,079$490$505$490$360$7,843$8,2034420$5,776$1,405$1,444$1,405$160$5,618$5,778-75%-56%-28%-30%
AntiviralsAntivirals, General1971384,171$5,105$16$26$22$2,130$3,085$5,2152041734,060$4,734$13$23$15$2,179$2,661$4,839-3%2%-14%-7%
AntiviralsAntiviral Nucleotide Analogs2210$0$0$0$0$24$0$242110$1,925$923$962$1,846$80$1,846$1,9260%233%0%7,926%
AntiviralsAntivirals, Hiv-Specific, Nucleoside Analog, Rti41120$670$153$167$612$60$612$6723190$542$166$181$499$45$499$544-25%-25%-18%-19%
AntiviralsSubtotal3151918,249$376,824$1,179$1,196$1,945$5,684$371,450$377,1343142168,247$446,869$1,405$1,423$2,043$5,764$441,262$447,026-0%1%19%19%
AntiarthriticsJanus Kinase (Jak) Inhibitors64540$120,015$19,922$20,002$29,884$480$119,535$120,01575630$142,708$20,307$20,387$28,430$560$142,148$142,70817%17%19%19%
AntiarthriticsAnti-Inflammatory Tumor Necrosis Factor Inhibitor127784$198,739$16,495$16,562$28,277$800$197,939$198,739148784$134,380$9,539$9,599$16,693$840$133,544$134,3840%5%-33%-32%
AntiarthriticsAnti-Inflammatory,phosphodiesterase-4(Pde4) Inhib.64356$58,847$9,748$9,808$14,622$360$58,489$58,84953330$60,705$12,077$12,141$20,129$320$60,386$60,706-7%-11%3%3%
AntiarthriticsAntinflammatory, Sel.Costim.Mod.,t-Cell Inhibitor32140$24,151$7,971$8,050$11,956$240$23,913$24,1531128$5,971$5,911$5,971$5,911$60$5,911$5,971-80%-75%-75%-75%
AntiarthriticsNsaids, Cyclooxygenase Inhibitor - Type51338610,683$3,622$2$7$3$2,886$1,051$3,9375173829,560$2,574$1$5$1$2,486$387$2,872-11%-14%-63%-27%
AntiarthriticsHyperuricemia Tx - Purine Inhibitors52282,882$921$16$18$29$119$820$93972414,160$1,789$21$25$36$333$1,479$1,81244%178%80%93%
AntiarthriticsNsaids, Cyclooxygenase 2 Inhibitor - Type42281,685$1,104$17$26$25$428$696$1,12445291,255$894$7$20$11$591$329$920-26%38%-53%-18%
AntiarthriticsColchicine126339$572$41$48$81$91$487$5781611574$517$25$32$36$124$399$52369%36%-18%-10%
AntiarthriticsAnti-Inflammatory, Pyrimidine Synthesis Inhibitor32270$446$149$149$223$0$446$44632150$150$40$50$60$30$121$151-44%0%-73%-66%
AntiarthriticsUricosuric Agents000$0$0$0$0$0$0$01130$80$65$80$65$15$65$800%0%0%0%
AntiarthriticsTopical Anti-Inflammatory, Nsaids37251,340$5,278$131$143$194$435$4,861$5,2961130$18$3$18$3$15$3$18-98%-97%-100%-100%
AntiarthriticsNsaids (Cox Non-Specific Inhib)& Prostaglandin Cmb1130$96$82$96$82$15$82$97000$0$0$0$0$0$0$0-100%-100%-100%-100%
AntiarthriticsSubtotal68746319,049$413,791$594$602$882$5,854$408,318$414,17268246017,531$349,783$506$513$750$5,373$344,773$350,146-8%-8%-16%-15%
All Other DermatologicalsAntipsoriatic Agents,systemic106618$175,783$17,503$17,578$29,172$755$175,030$175,785104504$146,086$14,531$14,609$36,327$780$145,306$146,086-18%3%-17%-17%
All Other DermatologicalsTopical Janus Kinase (Jak) Inhibitors128360$23,786$1,923$1,982$2,884$720$23,074$23,79487240$16,121$1,956$2,015$2,235$480$15,646$16,126-33%-33%-32%-32%
All Other DermatologicalsAcne Agents,topical2717915$9,960$353$369$560$450$9,525$9,9752821850$7,236$245$258$326$405$6,847$7,252-7%-10%-28%-27%
All Other DermatologicalsTopical Immunosuppressive Agents2518684$4,540$167$182$232$375$4,182$4,55742341,071$6,739$146$160$180$630$6,134$6,76457%68%47%48%
All Other DermatologicalsRosacea Agents, Topical2719883$5,759$200$213$284$375$5,400$5,77536251,074$6,042$155$168$223$495$5,566$6,06122%32%3%5%
All Other DermatologicalsAcne Agents,systemic2210660$5,907$254$269$559$330$5,592$5,922128360$4,133$330$344$495$180$3,960$4,140-45%-45%-29%-30%
All Other DermatologicalsVitamin A Derivatives34311,072$2,484$60$73$66$465$2,039$2,50469522,083$3,606$39$52$52$960$2,684$3,64494%106%32%46%
All Other DermatologicalsTopical Anticholinergic Hyperhidrosis Tx Agents000$0$0$0$0$0$0$052150$3,116$564$623$1,410$300$2,819$3,1190%0%0%0%
All Other DermatologicalsTopical Antiandrogenic Agents000$0$0$0$0$0$0$042120$2,345$527$586$1,054$240$2,107$2,3470%0%0%0%
All Other DermatologicalsAntipsoriatics Agents139390$1,812$125$139$181$195$1,625$1,82076270$846$111$121$129$75$774$849-31%-62%-52%-53%
All Other DermatologicalsAntiseborrheic Agents2250$148$60$74$60$30$120$1502260$66$19$33$19$29$38$6720%-5%-68%-55%
All Other DermatologicalsImmunomodulators44106$36$0$9$0$39$0$3975138$62$0$9$0$66$0$6630%71%0%71%
All Other DermatologicalsTop. Anti-Inflam.,phosphodiesterase-4 (Pde4) Inhib1130$739$700$739$700$40$700$740000$0$0$0$0$0$0$0-100%-100%-100%-100%
All Other DermatologicalsAntiperspirants1130$11$0$11$0$12$0$12000$0$0$0$0$0$0$0-100%-100%0%-100%
All Other DermatologicalsSubtotal1781115,798$230,968$1,277$1,298$2,048$3,786$227,286$231,0722301426,920$196,398$834$854$1,351$4,640$191,883$196,52219%23%-16%-15%
LipotropicsAntihyperlipidemic - Hmg Coa Reductase Inhibitors93451554,213$62,880$66$67$120$1,573$61,626$63,19999355157,659$66,495$66$67$118$1,672$65,137$66,8106%6%6%6%
LipotropicsAntihyperlipidemic - Pcsk9 Inhibitors33121,098$19,805$557$600$1,532$1,440$18,384$19,82461252,567$48,072$738$788$1,801$3,080$45,019$48,099134%114%145%143%
LipotropicsLipotropics160869,406$20,015$116$125$216$1,498$18,568$20,06717610211,258$15,583$83$89$143$1,070$14,557$15,62720%-29%-22%-22%
LipotropicsAntihyperlipidemic-Acly And Choles Absorp Inhib73210$2,773$357$396$833$280$2,498$2,77873210$2,838$366$405$854$280$2,562$2,8420%0%3%2%
LipotropicsAntihyperlipidemic - Atp Citrate Lyase Inhibitor52150$1,978$356$396$891$200$1,781$1,98141120$1,622$366$405$1,464$160$1,464$1,624-20%-20%-18%-18%
LipotropicsAntihyperlip.Hmg Coa Reduct Inhib&cholest.Ab.Inhib000$0$0$0$0$0$0$042120$189$33$47$66$60$131$1910%0%0%0%
LipotropicsSubtotal1,13956065,077$107,451$90$94$184$4,992$102,858$107,8491,24559771,934$134,798$104$108$216$6,322$128,872$135,19411%27%25%25%
Non-Opioid AnalgesicsAntimigraine Preparations105433,188$85,767$789$817$1,926$3,156$82,837$85,993112423,451$95,039$816$849$2,177$3,676$91,427$95,1038%16%10%11%
Non-Opioid AnalgesicsDrug Tx-Chronic Inflam. Colon Dx,5-Aminosalicylat157630$5,782$374$385$801$180$5,610$5,790128532$5,433$442$453$663$135$5,304$5,439-16%-25%-5%-6%
Non-Opioid AnalgesicsAnalgesic,non-Salicylate,barbiturate,&xanthine Cmb3316689$1,058$21$32$43$385$695$1,0803315553$1,387$30$42$65$430$976$1,406-20%12%40%30%
Non-Opioid AnalgesicsNsaids, Cyclooxygenase Inhibitor - Type2217489$418$5$19$7$314$118$4322319472$320$2$14$3$279$54$334-3%-11%-54%-23%
Non-Opioid AnalgesicsCalcitonin Gene-Related Peptide (Cgrp) Inhibitors1130$1,722$1,682$1,722$1,682$40$1,682$1,722000$0$0$0$0$0$0$0-100%-100%-100%-100%
Non-Opioid AnalgesicsSubtotal176795,026$94,748$517$538$1,151$4,076$90,943$95,018180795,008$102,180$543$568$1,237$4,521$97,761$102,282-0%11%7%8%
Other HormonesGrowth Hormones42347$114,064$28,416$28,516$56,832$400$113,664$114,06463308$83,136$13,789$13,856$27,579$400$82,736$83,136-11%0%-27%-27%
Other HormonesLhrh (Gnrh) Antagonist,estrogen And Progestin000$0$0$0$0$0$0$063224$9,422$1,524$1,570$3,048$280$9,145$9,4250%0%0%0%
Other HormonesPregnancy Facilitating/Maintaining Agent,hormonal41120$3,045$722$761$2,888$160$2,888$3,0483145$2,725$869$908$2,607$120$2,607$2,727-63%-25%-10%-11%
Other HormonesFertility Stimulating Preparations,non-Fsh1311461$1,723$124$133$146$120$1,607$1,727116445$2,225$193$202$354$105$2,124$2,229-3%-13%32%29%
Other HormonesAntidiuretic And Vasopressor Hormones000$0$0$0$0$0$0$03190$146$34$49$103$45$103$1480%0%0%0%
Other HormonesPituitary Suppressive Agents33204$353$113$118$113$15$338$3531184$58$58$58$58$0$58$58-59%-100%-83%-83%
Other HormonesLhrh(Gnrh) Antagonist,pituitary Suppressant Agents116$1,848$1,833$1,848$1,833$15$1,833$1,848000$0$0$0$0$0$0$0-100%-100%-100%-100%
Other HormonesLhrh(Gnrh) Agonist Analog Pituitary Suppressants1128$1,728$1,689$1,728$1,689$40$1,689$1,729000$0$0$0$0$0$0$0-100%-100%-100%-100%
Other HormonesHuman Chorionic Gonadotropin (Hcg)1114$320$280$320$280$40$280$320000$0$0$0$0$0$0$0-100%-100%-100%-100%
Other HormonesFollicle-Stimulating Hormone (Fsh)116$2,956$2,916$2,956$2,916$40$2,916$2,956000$0$0$0$0$0$0$0-100%-100%-100%-100%
Other HormonesBone Resorption Inhibitors1130$45$30$45$30$15$30$45000$0$0$0$0$0$0$0-100%-100%-100%-100%
Other HormonesSubtotal29191,216$126,081$4,319$4,348$6,592$845$125,245$126,09030151,196$97,712$3,226$3,257$6,452$950$96,773$97,723-2%12%-23%-22%
BiologicalsIl-23 Receptor Antagonist, Monoclonal Antibod000$0$0$0$0$0$0$02284$32,862$16,371$16,431$16,371$120$32,742$32,8620%0%0%0%
BiologicalsMonoclonal Antibody - Interleukin-5 Antagonists1184$11,421$11,341$11,421$11,341$80$11,341$11,42141112$16,122$3,991$4,031$15,964$160$15,964$16,12433%100%41%41%
BiologicalsViral/Tumorigenic Vaccines614961$12,089$217$198$270$0$13,249$13,249403598$7,999$225$200$257-$80$8,998$8,91861%0%-32%-33%
BiologicalsInterleukin-5(Il-5) Receptor Alpha Antagonist, Mab000$0$0$0$0$0$0$01156$6,017$5,937$6,017$5,937$80$5,937$6,0170%0%0%0%
BiologicalsGram Positive Cocci Vaccines555$1,129$242$226$242$0$1,212$1,212171717$4,474$289$263$289-$25$4,910$4,885240%0%305%303%
BiologicalsVaccine/Toxoid Preparations,combinations191819$910$67$48$71$0$1,282$1,282262555$1,439$81$55$84-$40$2,104$2,064189%0%64%61%
BiologicalsCovid-19 Vaccines131313$1,613$164$124$164$0$2,133$2,133101010$1,326$173$133$173-$80$1,730$1,650-23%0%-19%-23%
BiologicalsInfluenza Virus Vaccines292929$925$48$32$48$0$1,379$1,379242424$986$62$41$62-$55$1,481$1,426-17%0%7%3%
BiologicalsEnteric Virus Vaccines000$0$0$0$0$0$0$0333$119$65$40$65-$5$196$1910%0%0%0%
BiologicalsGram Negative Cocci Vaccines222$337$179$168$179$0$358$358111$161$186$161$186$0$186$186-50%0%-48%-48%
BiologicalsAntipsoriatic Agents,systemic1156$13,516$13,436$13,516$13,436$80$13,436$13,516000$0$0$0$0$0$0$0-100%-100%-100%-100%
BiologicalsSubtotal13189269$41,940$339$320$499$160$44,391$44,55112884460$71,505$580$559$884$75$74,248$74,32371%-53%67%67%
Bronchial DilatorsBeta-Adrenergic-Anticholinergic-Glucocort, Inhaled34161,140$23,863$660$702$1,403$1,440$22,444$23,88434181,440$30,324$845$892$1,597$1,600$28,740$30,34026%11%28%27%
Bronchial DilatorsBeta-Adrenergic And Glucocorticoid Combo, Inhaled68413,292$28,559$401$420$665$1,320$27,269$28,58989513,433$28,963$305$325$531$1,905$27,103$29,0084%44%-1%1%
Bronchial DilatorsBeta-Adrenergic Agents, Inhaled, Short Acting2711816,661$9,177$21$34$31$3,698$5,649$9,3482731827,041$6,332$11$23$16$3,572$2,913$6,4856%-3%-48%-31%
Bronchial DilatorsLeukotriene Receptor Antagonists111766,810$1,763$13$16$19$363$1,434$1,796112726,207$1,294$8$12$13$381$951$1,332-9%5%-34%-26%
Bronchial DilatorsBeta-Adrenergic And Anticholinergic Combo, Inhaled1614487$1,642$89$103$101$233$1,417$1,6501714394$1,220$57$72$69$266$964$1,230-19%14%-32%-25%
Bronchial DilatorsAnticholinergics, Orally Inhaled Long Acting3190$1,488$457$496$1,370$120$1,370$1,4901160$477$397$477$397$80$397$477-33%-33%-71%-68%
Bronchial DilatorsAnticholinergic, Orally Inhaled Short Acting87288$2,271$259$284$296$203$2,072$2,2753355$314$86$105$86$59$257$315-81%-71%-88%-86%
Bronchial DilatorsSubtotal51126118,768$68,763$121$135$236$7,377$61,655$69,03252925818,630$68,923$116$130$238$7,862$61,324$69,187-1%7%-1%0%
AnticoagulantsDirect Factor Xa Inhibitors60332,714$49,330$772$822$1,404$3,040$46,318$49,35855272,700$50,238$860$913$1,752$2,960$47,299$50,259-1%-3%2%2%
AnticoagulantsPlatelet Aggregation Inhibitors65343,688$16,104$227$248$434$1,386$14,740$16,12677384,095$13,664$162$177$328$1,229$12,463$13,69211%-11%-15%-15%
AnticoagulantsHeparin And Related Preparations3345$1,295$417$432$417$45$1,252$1,29754186$946$177$189$222$60$887$947313%33%-29%-27%
AnticoagulantsAnticoagulants,coumarin Type114684$121$8$11$23$33$92$125113372$237$16$22$57$71$172$243-46%118%88%96%
AnticoagulantsSubtotal139717,131$66,850$449$481$879$4,504$62,402$66,906148727,353$65,085$411$440$845$4,321$60,821$65,1413%-4%-3%-3%
Medical SuppliesDiabetic Supplies116466,351$51,254$385$442$971$6,640$44,657$51,297137636,193$63,475$412$463$897$7,053$56,480$63,533-2%6%26%24%
Medical SuppliesNeedles/Needleless Devices38302,397$2,044$48$54$61$218$1,837$2,05551372,776$2,589$45$51$62$299$2,305$2,60416%37%25%27%
Medical SuppliesDurable Medical Equipment,misc(Group 1)37332,215$483$9$13$11$144$351$49537271,756$414$6$11$8$223$206$429-21%55%-41%-13%
Medical SuppliesSyringes And Accessories99583$157$16$17$16$19$140$15998544$124$8$14$9$52$74$126-7%170%-47%-21%
Medical SuppliesRespiratory Aids,devices,equipment99301$243$0$27$0$248$0$248000$0$0$0$0$0$0$0-100%-100%0%-100%
Medical SuppliesSubtotal20910511,847$54,182$225$259$447$7,269$46,985$54,25423411711,269$66,601$252$285$505$7,627$59,065$66,692-5%5%26%23%
Other Cardiovascular PrepsAngiotensin Recept-Neprilysin Inhibitor Comb(Arni)39171,830$39,115$952$1,003$2,184$2,000$37,133$39,13349232,190$48,037$931$980$1,983$2,440$45,619$48,05920%22%23%23%
Other Cardiovascular PrepsBeta-Adrenergic Blocking Agents34718020,011$6,191$15$18$29$1,029$5,281$6,31036618820,984$5,303$11$14$21$1,420$4,000$5,4205%38%-24%-14%
Other Cardiovascular PrepsCalcium Channel Blocking Agents46425025,200$5,683$10$12$18$1,422$4,440$5,86146426526,140$4,603$8$10$13$1,201$3,557$4,7584%-16%-20%-19%
Other Cardiovascular PrepsAlpha/Beta-Adrenergic Blocking Agents106575,194$1,486$9$14$17$567$964$1,531110575,580$2,070$14$19$27$562$1,551$2,1137%-1%61%38%
Other Cardiovascular PrepsAntiarrhythmics2491,140$1,495$54$62$144$213$1,292$1,506189960$1,271$63$71$125$152$1,125$1,277-16%-29%-13%-15%
Other Cardiovascular PrepsBeta-Adrenergic Blocking Agents/Thiazide & Related137632$353$18$27$33$126$233$359166722$409$15$26$39$180$236$41614%43%1%16%
Other Cardiovascular PrepsHemorrheologic Agents1190$119$119$119$119$0$119$11922180$180$90$90$90$0$180$180100%0%51%51%
Other Cardiovascular PrepsAntianginal & Anti-Ischemic Agents,non-Hemodynamic3190$176$44$59$133$45$133$178000$0$0$0$0$0$0$0-100%-100%-100%-100%
Other Cardiovascular PrepsSubtotal99742454,187$54,618$50$55$117$5,402$49,596$54,9981,02544756,756$61,871$55$60$126$5,955$56,268$62,2225%10%13%13%
Other AntihypertensivesPulmonary Anti-Htn, Endothelin Receptor Antagonist62240$65,239$10,861$10,873$32,582$75$65,164$65,2391190$16,698$16,698$16,698$16,698$0$16,698$16,698-63%-100%-74%-74%
Other AntihypertensivesAntihypertensives, Angiotensin Receptor Antagonist45923925,414$8,395$14$18$27$2,105$6,461$8,56647325827,433$6,893$11$15$20$1,855$5,188$7,0438%-12%-20%-18%
Other AntihypertensivesPulm.Anti-Htn,sel.C-Gmp Phosphodiesterase T5 Inhib32190$6,836$2,274$2,279$3,411$15$6,822$6,83753330$5,811$1,156$1,162$1,927$30$5,782$5,81274%100%-15%-15%
Other AntihypertensivesAngiotensin Receptor Antag./Thiazide Diuretic Comb19010211,283$8,262$38$43$70$1,156$7,169$8,3241819910,710$5,144$23$28$42$1,028$4,171$5,200-5%-11%-42%-38%
Other AntihypertensivesAntihypertensives, Ace Inhibitors28516418,047$2,811$9$10$15$441$2,452$2,89325715616,631$2,018$7$8$11$388$1,694$2,083-8%-12%-31%-28%
Other AntihypertensivesAngiotensin Receptor Antgnst & Calc.Channel Blockr20141,500$2,241$108$112$155$75$2,169$2,24419141,470$1,517$77$80$104$60$1,460$1,520-2%-20%-33%-32%
Other AntihypertensivesAngioten.Receptr Antag./Cal.Chanl Blkr/Thiazide C95510$1,219$128$135$230$75$1,148$1,223126600$1,198$91$100$183$105$1,097$1,20218%40%-4%-2%
Other AntihypertensivesAntihypertensives, Vasodilators39211,890$452$8$12$15$158$310$46961353,288$749$8$12$14$297$473$77174%88%53%64%
Other AntihypertensivesAce Inhibitor/Calcium Channel Blocker Combination31172,010$766$20$25$37$144$631$77532182,040$638$15$20$27$153$494$6461%6%-22%-17%
Other AntihypertensivesAce Inhibitor/Thiazide & Thiazide-Like Diuretic48343,240$695$13$14$19$70$637$70737252,490$446$10$12$14$94$361$455-23%34%-43%-36%
Other AntihypertensivesAlpha-Adrenergic Blocking Agents1912965$378$16$20$25$90$296$386107600$185$14$18$20$47$141$188-38%-48%-52%-51%
Other AntihypertensivesAntihypertensives, Sympatholytic29151,471$179$5$6$10$45$146$1901710862$83$3$5$6$31$59$89-41%-32%-60%-53%
Other AntihypertensivesPulmonary Antihypertensives, Prostacyclin-Type51150$118,235$23,607$23,647$118,035$200$118,035$118,235000$0$0$0$0$0$0$0-100%-100%-100%-100%
Other AntihypertensivesSubtotal1,14357466,910$215,707$185$189$368$4,649$211,437$216,0861,10559166,544$41,380$34$37$64$4,087$37,619$41,706-1%-12%-82%-81%
AnticonvulsantsAnticonvulsants29214612,140$35,582$113$122$225$2,807$32,919$35,72628414413,073$31,459$102$111$200$2,720$28,857$31,5778%-3%-12%-12%
AnticonvulsantsAnticonvulsant - Benzodiazepine Type63311,936$1,070$11$17$23$392$714$1,10680332,331$2,181$21$27$52$509$1,715$2,22520%30%140%101%
AnticonvulsantsSubtotal35516914,076$36,652$95$103$199$3,199$33,634$36,83236416415,404$33,640$84$92$186$3,229$30,572$33,8029%1%-9%-8%
Systemic ContraceptivesContraceptives,oral30914515,102$29,003$81$94$172$4,114$25,012$29,12724311511,409$15,283$56$63$118$1,767$13,613$15,379-24%-57%-46%-47%
Systemic ContraceptivesContraceptives, Intravaginal, Systemic30131,696$7,073$232$236$536$120$6,966$7,0862110996$5,420$253$258$531$120$5,308$5,428-41%0%-24%-23%
Systemic ContraceptivesContraceptives,transdermal94342$1,232$137$137$309$0$1,237$1,23752188$1,136$228$227$569$0$1,139$1,139-45%0%-8%-8%
Systemic ContraceptivesContraceptives,injectable1184$39$39$39$39$0$39$3933264$150$50$50$50$0$150$150214%0%281%281%
Systemic ContraceptivesSubtotal34916317,224$37,347$95$107$204$4,234$33,255$37,48927212912,857$21,989$74$81$157$1,887$20,210$22,096-25%-55%-39%-41%
Amphetamine PreparationsAdrenergics, Aromatic, Non-Catecholamine148584,762$17,823$101$120$257$3,017$14,893$17,910199736,578$20,793$86$104$235$3,741$17,158$20,89938%24%15%17%
Amphetamine PreparationsSubtotal148584,762$17,823$101$120$257$3,017$14,893$17,910199736,578$20,793$86$104$235$3,741$17,158$20,89938%24%15%17%
AntifungalsAntifungal Agents122891,315$27,636$220$227$301$890$26,822$27,712121911,061$14,588$116$121$154$664$13,995$14,659-19%-25%-48%-47%
AntifungalsTopical Antifungals1521154,337$3,457$10$23$13$2,018$1,530$3,5481521104,229$4,586$18$30$24$2,007$2,661$4,668-2%-1%74%32%
AntifungalsTopical Antifungal/Antiinflammatory,steriod Agent3027623$329$1$11$1$332$16$3482726648$508$7$19$8$322$201$5224%-3%1,165%50%
AntifungalsVaginal Antifungals181594$597$19$33$23$270$339$609111162$288$12$26$12$165$130$295-34%-39%-62%-52%
AntifungalsAntifungal Antibiotics65100$314$39$52$47$83$235$3185480$36$0$7$0$37$1$39-20%-55%-99%-88%
AntifungalsSubtotal3282216,469$32,333$88$99$131$3,593$28,942$32,5353162176,080$20,006$54$63$78$3,195$16,987$20,183-6%-11%-41%-38%
Psychostimulants-AntidepressantsSsri & Serotonin Receptor Modulator Antidepressant54270$4,080$744$816$931$360$3,722$4,08262300$4,774$743$796$2,228$320$4,456$4,77611%-11%20%17%
Psychostimulants-AntidepressantsNorepinephrine And Dopamine Reuptake Inhib (Ndris)101565,475$3,818$30$38$55$801$3,054$3,855107555,640$3,463$24$32$47$920$2,579$3,5003%15%-16%-9%
Psychostimulants-AntidepressantsSelective Serotonin Reuptake Inhibitor (Ssris)34916717,725$4,037$8$12$18$1,237$2,946$4,18237518118,534$3,349$6$9$13$1,225$2,274$3,4995%-1%-23%-16%
Psychostimulants-AntidepressantsTx For Attention Deficit-Hyperact.(Adhd), Nri-Type26121,003$2,824$98$109$212$288$2,549$2,8372710962$2,264$69$84$187$405$1,874$2,279-4%41%-26%-20%
Psychostimulants-AntidepressantsNdma Receptor Antagonist And Ndri Comb000$0$0$0$0$0$0$041120$2,273$509$568$2,035$240$2,035$2,2750%0%0%0%
Psychostimulants-AntidepressantsSerotonin-Norepinephrine Reuptake-Inhib (Snris)39242,123$1,837$41$47$66$272$1,580$1,85162292,986$1,755$22$28$47$417$1,364$1,78141%53%-14%-4%
Psychostimulants-AntidepressantsSerotonin-2 Antagonist/Reuptake Inhibitors (Saris)61323,239$925$12$15$23$208$740$94865423,168$598$6$9$9$246$378$624-2%18%-49%-34%
Psychostimulants-AntidepressantsSsri & 5ht1a Partial Agonist Antidepressant32150$476$149$159$224$30$447$47722180$448$224$224$224$0$448$44820%-100%0%-6%
Psychostimulants-AntidepressantsTricyclic Antidepressants & Rel. Non-Sel. Ru-Inhib23111,160$360$11$16$23$121$248$36929151,364$400$10$14$19$124$288$41218%2%16%11%
Psychostimulants-AntidepressantsAlpha-2 Receptor Antagonist Antidepressants189930$662$32$37$64$90$579$669228900$301$7$14$19$161$151$312-3%78%-74%-53%
Psychostimulants-AntidepressantsNarcolepsy And Sleep Disorder Therapy Agents66232$285$36$48$36$74$213$28832210$169$52$56$77$15$155$170-9%-80%-27%-41%
Psychostimulants-AntidepressantsTx For Adhd - Selective Alpha-2a Receptor Agonist93330$215$11$24$33$120$100$220105285$118$0$12$0$124$0$124-14%4%-100%-44%
Psychostimulants-AntidepressantsBipolar Disorder Drugs000$0$0$0$0$0$0$01131$10$0$10$0$11$0$110%0%0%0%
Psychostimulants-AntidepressantsSubtotal64026632,637$19,520$25$31$61$3,600$16,179$19,77971328934,680$19,923$22$28$55$4,206$16,003$20,2096%17%-1%2%
Ophthalmic PreparationsOphthalmic Anti-Inflammatory Immunomodulator-Type24131,350$20,848$841$869$1,553$665$20,191$20,856157630$8,677$554$578$1,187$375$8,309$8,684-53%-44%-59%-58%
Ophthalmic PreparationsMiotics/Other Intraoc. Pressure Reducers98424,434$6,314$57$64$133$771$5,584$6,355106505,286$5,644$45$53$95$928$4,750$5,67819%20%-15%-11%
Ophthalmic PreparationsEye Antiinflammatory Agents54351,385$4,323$65$80$101$827$3,525$4,35252351,302$1,985$26$38$38$675$1,340$2,015-6%-18%-62%-54%
Ophthalmic PreparationsOphthalmic Antibiotics76671,349$968$4$13$4$738$274$1,01280691,284$979$1$12$1$941$85$1,026-5%28%-69%1%
Ophthalmic PreparationsArtificial Tears1130$747$688$747$688$60$688$7481130$774$748$774$748$40$748$7880%-33%9%5%
Ophthalmic PreparationsEye Antibiotic-Corticoid Combinations3125555$1,747$41$56$51$498$1,267$1,7663730568$761$7$21$9$527$256$7832%6%-80%-56%
Ophthalmic PreparationsMydriatics117$47$33$47$33$15$33$4875262$226$23$32$32$67$162$2293,643%350%393%379%
Ophthalmic PreparationsOphthalmic Mast Cell Stabilizers2248$44$8$22$8$28$17$441137$17$17$17$17$0$17$17-23%-100%2%-62%
Ophthalmic PreparationsOphthalmic (Eye) Antiparasitics1150$1,864$1,784$1,864$1,784$80$1,784$1,864000$0$0$0$0$0$0$0-100%-100%-100%-100%
Ophthalmic PreparationsSubtotal2881589,208$36,900$116$128$211$3,682$33,363$37,0452991579,399$19,064$52$64$100$3,553$15,667$19,2212%-3%-53%-48%
AdrenergicsAnaphylaxis Therapy Agents1515286$6,382$409$425$409$255$6,136$6,3912121183$6,788$308$323$308$340$6,461$6,801-36%33%5%6%
AdrenergicsOveractive Bladder Agents, Beta-3 Adrenergic Recep41120$1,774$384$443$1,536$240$1,536$1,77694392$4,513$490$501$1,103$105$4,412$4,517227%-56%187%154%
AdrenergicsAdrenergic Vasopressor Agents2260$42$9$21$9$25$18$433261$90$20$30$30$31$60$922%23%241%113%
AdrenergicsSubtotal2118466$8,197$366$390$427$520$7,690$8,2103327636$11,391$331$345$405$476$10,934$11,41036%-8%42%39%
AndrogensAndrogenic Agents78382,857$7,181$79$92$163$1,025$6,195$7,22088443,177$11,381$114$129$227$1,470$9,998$11,46811%43%61%59%
AndrogensAndrogen/Estrogen Preps For Female Sexual Dysfunc000$0$0$0$0$0$0$041112$1,114$219$279$877$240$877$1,1170%0%0%0%
AndrogensSubtotal78382,857$7,181$79$92$163$1,025$6,195$7,22092453,289$12,496$118$136$242$1,710$10,874$12,58415%67%76%74%
Topical Nasal And Otic PreparationsNasal Anti-Inflammatory Steroids1841588,678$3,361$12$18$14$1,197$2,240$3,4381901509,316$6,535$27$34$35$1,425$5,181$6,6057%19%131%92%
Topical Nasal And Otic PreparationsOtic Preparations,anti-Inflammatory-Antibiotics109167$1,961$182$196$202$150$1,818$1,9681513232$2,722$162$181$187$300$2,431$2,73139%100%34%39%
Topical Nasal And Otic PreparationsNose Preparations, Miscellaneous (Rx)108624$527$47$53$59$60$470$53025181,343$1,057$34$42$48$210$855$1,065115%250%82%101%
Topical Nasal And Otic PreparationsNasal Antihistamine54422,790$2,162$33$40$43$388$1,792$2,18037311,932$936$19$25$23$246$702$948-31%-37%-61%-57%
Topical Nasal And Otic PreparationsNasal Antihistamine & Anti-Inflam. Steroid Comb.1110634$2,044$179$186$197$75$1,972$2,04799330$760$72$84$72$120$645$765-48%60%-67%-63%
Topical Nasal And Otic PreparationsEar Preparations,antibiotics2220212$788$22$36$24$319$483$8021918279$671$22$35$23$266$417$68332%-17%-14%-15%
Topical Nasal And Otic PreparationsEar Preparations Anti-Inflammatory3390$179$45$60$45$45$136$18155174$226$37$45$37$45$183$22893%0%35%26%
Topical Nasal And Otic PreparationsEar Preparations, Misc. Anti-Infectives1118$101$87$101$87$15$87$1023338$198$52$66$52$45$155$200111%200%79%97%
Topical Nasal And Otic PreparationsSubtotal29521813,213$11,123$30$38$41$2,249$8,997$11,24630322013,644$13,106$35$43$48$2,656$10,569$13,2253%18%17%18%
GlucocorticoidsTopical Anti-Inflammatory Steroidal2251726,223$6,682$20$30$27$2,211$4,605$6,8172421886,224$7,301$21$30$27$2,331$5,105$7,4360%5%11%9%
GlucocorticoidsGlucocorticoids, Orally Inhaled40301,424$7,436$161$186$214$1,030$6,426$7,45635251,372$5,078$120$145$167$910$4,185$5,095-4%-12%-35%-32%
GlucocorticoidsGlucocorticoids3002552,951$9,848$28$33$32$1,779$8,259$10,0393192423,538$1,996$2$6$2$1,601$584$2,18420%-10%-93%-78%
GlucocorticoidsRectal/Lower Bowel Prep.,glucocort. (Non-Hemorr)1128$368$354$368$354$15$354$369000$0$0$0$0$0$0$0-100%-100%-100%-100%
GlucocorticoidsSubtotal56642610,626$24,334$35$43$46$5,036$19,644$24,68059641811,134$14,375$17$24$24$4,842$9,874$14,7165%-4%-50%-40%
Ataractics-TranquilizersAntipsychotics, Atyp, D2 Partial Agonist/5ht Mixed23131,230$8,222$343$357$607$337$7,894$8,2312011990$4,457$211$223$383$254$4,210$4,464-20%-24%-47%-46%
Ataractics-TranquilizersAntipsychotic-Atypical,d3/D2 Partial Ag-5ht Mixed21120$5,324$2,572$2,662$5,145$180$5,145$5,3252160$2,932$1,407$1,466$2,813$120$2,813$2,933-50%-33%-45%-45%
Ataractics-TranquilizersAntipsychotics,atypical,dopamine,& Serotonin Antag59192,335$2,667$39$45$123$367$2,330$2,69781283,668$2,238$20$28$59$629$1,644$2,27357%71%-29%-16%
Ataractics-TranquilizersAnti-Anxiety - Benzodiazepines142783,885$1,150$3$8$5$850$389$1,239141763,642$1,052$2$7$4$813$321$1,134-6%-4%-18%-8%
Ataractics-TranquilizersAnti-Anxiety Drugs45251,925$649$9$14$15$285$386$67156302,211$421$3$8$6$259$190$44915%-9%-51%-33%
Ataractics-TranquilizersAntipsychotics,dopamine Antagonists,butyrophenones51150$288$43$58$216$75$216$29141120$195$34$49$137$60$137$197-20%-20%-36%-32%
Ataractics-TranquilizersSubtotal2761239,645$18,300$59$66$133$2,094$16,361$18,45430412910,691$11,295$31$37$72$2,135$9,316$11,45011%2%-43%-38%
Hematinics & Blood Cell StimulatorsLeukocyte (Wbc) Stimulants6184$23,724$3,915$3,954$23,488$240$23,488$23,7282229$4,750$2,335$2,375$2,335$80$4,671$4,751-65%-67%-80%-80%
Hematinics & Blood Cell StimulatorsIron Replacement107420$1,546$112$155$159$436$1,116$1,551105360$4,256$372$426$743$575$3,717$4,292-14%32%233%177%
Hematinics & Blood Cell StimulatorsSubtotal168504$25,270$1,538$1,579$3,075$676$24,604$25,279127389$9,006$699$751$1,198$655$8,388$9,043-23%-3%-66%-64%
EstrogensEstrogenic Agents36201,972$5,488$137$152$247$566$4,934$5,50089413,858$6,146$58$69$126$1,010$5,173$6,18396%78%5%12%
EstrogensVaginal Estrogen Preparations26222,519$4,147$146$159$173$355$3,796$4,15140303,339$3,370$76$84$101$355$3,023$3,37833%0%-20%-19%
EstrogensSubtotal62414,491$9,635$141$155$213$921$8,730$9,651129617,197$9,515$64$74$134$1,365$8,195$9,56060%48%-6%-1%
Cns StimulantsTx For Attention Deficit-Hyperact(Adhd)/Narcolepsy52251,634$7,637$124$147$259$1,200$6,468$7,66878332,497$7,910$83$101$196$1,479$6,474$7,95453%23%0%4%
Cns StimulantsSmoking Deterrent-Nicotinic Recept.Partial Agonist42101$872$219$218$437$0$875$8753288$622$198$207$297$30$593$623-13%0%-32%-29%
Cns StimulantsSmoking Deterrent Agents (Ganglionic Stim,others)000$0$0$0$0$0$0$063170$273$36$46$72$60$217$2770%0%0%0%
Cns StimulantsSubtotal56271,735$8,509$131$152$272$1,200$7,343$8,54387372,755$8,805$84$101$197$1,569$7,284$8,85359%31%-1%4%
Other AntibioticsRifamycins And Related Derivative Antibiotics2228$4,446$2,183$2,223$2,183$80$4,367$4,4472128$4,680$2,300$2,340$4,601$80$4,601$4,6810%0%5%5%
Other AntibioticsTopical Antibiotics120992,356$2,290$10$19$12$1,211$1,155$2,3661551243,430$3,218$11$21$14$1,608$1,698$3,30746%33%47%40%
Other AntibioticsVaginal Antibiotics1414102$778$41$56$41$210$577$787141386$572$26$41$29$210$371$581-16%0%-36%-26%
Other AntibioticsLincosamides1917161$309$7$16$8$192$129$3211917173$337$10$18$11$168$181$3497%-13%40%9%
Other AntibioticsQuinolones4138426$191$0$5$0$207$10$2183229333$137$1$4$1$126$30$156-22%-39%192%-28%
Other AntibioticsSubtotal1961653,073$8,014$32$41$38$1,900$6,239$8,1392221764,050$8,945$31$40$39$2,192$6,881$9,07332%15%10%11%
Anti-Ulcer Preps/Gastrointestinal PrepsProton-Pump Inhibitors35123119,257$10,588$27$30$40$1,390$9,325$10,71535722120,087$4,946$11$14$18$1,059$4,003$5,0634%-24%-57%-53%
Anti-Ulcer Preps/Gastrointestinal PrepsPotassium-Competitive Acid Blockers (Pcabs)000$0$0$0$0$0$0$03190$1,976$611$659$1,833$180$1,833$2,0130%0%0%0%
Anti-Ulcer Preps/Gastrointestinal PrepsHistamine H2-Receptor Inhibitors126845,629$1,732$10$14$15$537$1,253$1,790138805,746$916$3$7$6$505$475$9802%-6%-62%-45%
Anti-Ulcer Preps/Gastrointestinal PrepsAnti-Ulcer Preparations1514304$576$29$38$31$153$432$5851010123$412$32$41$32$95$324$418-60%-38%-25%-29%
Anti-Ulcer Preps/Gastrointestinal PrepsAnti-Ulcer-H.Pylori Agents1115$792$778$792$778$15$778$793000$0$0$0$0$0$0$0-100%-100%-100%-100%
Anti-Ulcer Preps/Gastrointestinal PrepsSubtotal49330125,205$13,688$24$28$39$2,096$11,788$13,88450829626,046$8,251$13$16$22$1,839$6,635$8,4743%-12%-44%-39%
EnzymesPancreatic Enzymes1190$4,270$4,150$4,270$4,150$120$4,150$4,2701190$4,457$4,377$4,457$4,377$80$4,377$4,4570%-33%5%4%
EnzymesTopical/Mucous Membr./Subcut. Enzymes000$0$0$0$0$0$0$02260$1,180$551$590$551$80$1,101$1,1810%0%0%0%
EnzymesSubtotal1190$4,270$4,150$4,270$4,150$120$4,150$4,27033150$5,637$1,826$1,879$1,826$160$5,478$5,63867%33%32%32%
HemostaticsAntifibrinolytic Agents77170$1,080$142$154$142$90$994$1,08412790$5,279$426$440$729$179$5,106$5,286-47%99%414%388%
HemostaticsThrombopoietin Receptor Agonists1130$41,805$41,745$41,805$41,745$60$41,745$41,805000$0$0$0$0$0$0$0-100%-100%-100%-100%
HemostaticsSubtotal88200$42,885$5,342$5,361$5,342$150$42,739$42,88912790$5,279$426$440$729$179$5,106$5,286-55%20%-88%-88%
AntiparasiticsAnthelmintics212$119$45$60$90$30$90$120113$4,320$4,306$4,320$4,306$15$4,306$4,32150%-50%4,668%3,492%
AntiparasiticsAntiprotozoal Drugs,miscellaneous4195$1,781$431$445$1,724$60$1,724$1,7842142$577$274$288$548$30$548$578-56%-50%-68%-68%
AntiparasiticsAnaerobic Antiprotozoal-Antibacterial Agents4139334$339$3$8$3$238$127$3654941390$188$0$4$0$218$0$21817%-8%-100%-40%
Antiparasitics2nd Gen. Anaerobic Antiprotozoal-Antibacterial6525$202$19$34$23$90$116$2063315$77$11$26$11$45$34$79-40%-50%-71%-62%
AntiparasiticsTopical Antiparasitics2229$54$13$27$13$30$25$551114$19$5$19$5$15$5$20-52%-50%-80%-64%
AntiparasiticsSubtotal5543485$2,495$38$45$48$448$2,083$2,5305647464$5,182$87$93$104$323$4,892$5,215-4%-28%135%106%
Thyroid PrepsThyroid Hormones25213415,992$5,318$17$21$32$1,098$4,292$5,39026514416,776$5,220$16$20$30$979$4,310$5,2895%-11%0%-2%
Thyroid PrepsSubtotal25213415,992$5,318$17$21$32$1,098$4,292$5,39026514416,776$5,220$16$20$30$979$4,310$5,2895%-11%0%-2%
LaxativesLaxatives And Cathartics9787399$10,620$107$109$120$279$10,402$10,6826862385$3,263$46$48$50$188$3,116$3,303-4%-33%-70%-69%
LaxativesSubtotal9787399$10,620$107$109$120$279$10,402$10,6826862385$3,263$46$48$50$188$3,116$3,303-4%-33%-70%-69%
Antispasmodic And Anticholinergic AgentsAnticholinergics,quaternary Ammonium22101,038$4,084$176$186$387$225$3,868$4,0931410632$2,053$138$147$193$126$1,932$2,058-39%-44%-50%-50%
Antispasmodic And Anticholinergic AgentsUrinary Tract Antispasmodic/Antiincontinence Agent74307$561$71$80$125$64$500$56483300$350$31$44$83$105$249$354-2%64%-50%-37%
Antispasmodic And Anticholinergic AgentsAnticholinergics/Antispasmodics2823769$620$14$22$17$250$386$6353123784$315$4$10$5$216$115$3322%-13%-70%-48%
Antispasmodic And Anticholinergic AgentsUrinary Tract Antispasmodic, M(3) Selective Antag.21180$94$47$47$94$0$94$9494540$290$26$32$58$60$232$292200%0%146%209%
Antispasmodic And Anticholinergic AgentsBelladonna Alkaloids116272$327$19$30$34$128$206$33464190$229$28$38$42$65$168$232-30%-50%-19%-30%
Antispasmodic And Anticholinergic AgentsSubtotal70422,566$5,686$72$81$120$667$5,054$5,72168442,446$3,237$40$48$61$572$2,696$3,268-5%-14%-47%-43%

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