Amendment 1 - 75N96020R00005 Q&A.pdf

This document provides an amendment to a request for proposals and details of a related federal contract opportunity. The National Institute of Environmental Health Sciences intends to award an indefinite delivery/indefinite quantity contract for up to ten years to examine chemicals for their ability to induce genetic changes in cells and animals. Services may include comet assays, micronucleus assays, and other studies on approximately 20 chemicals annually to evaluate endpoints such as DNA damage, chromosomal changes, and gene expression profiles. The contract will also include a research and development effort to refine existing techniques and integrate new technologies for maintaining scientific capability. The pre-proposal questions are due by December 20, 2019, and the agency aims to negotiate and award the contract to examine chemicals submitted by the National Toxicology Program.