Autogen Inc.

Autogen Inc., a self-certified small disadvantaged business based in Holliston, Massachusetts, manufactures and services DNA and RNA extraction systems as a prime contractor to federal research agencies, competing exclusively full-and-open with no set-aside designations across its 170 federal awards since 1999. Autogen is a for-profit Subchapter S Corporation specializing in automated nucleic acid processing equipment, including the AutoGen Flex STARR, AutoGen GenePREP with Stacker, and AUTOGEN XTRACT 16+ systems, along with preventive maintenance, service agreements, and extended service support for government-owned instruments deployed across the National Institutes of Health, the Smithsonian Institution, the U.S. Department of Agriculture, and the U.S. Geological Survey.

Customer concentration sits heavily with biomedical research agencies. The top five funding agencies account for 56% of recent awards by count, led by the National Human Genome Research Institute (34 awards, $342 thousand combined potential value), the Smithsonian Institution (19 awards, $318 thousand), and the National Cancer Institute (19 awards, $719 thousand combined potential value). The two rankings diverge slightly on dollars — the National Cancer Institute holds the largest combined potential value share at $719 thousand, followed by the Department of Agriculture's Agricultural Research Service (14 awards, $657 thousand), and the National Heart, Lung and Blood Institute (2 awards, $278 thousand) — signaling that while NHGRI dominates by order volume, the larger dollar awards flow to cancer and agricultural genomics work. Autogen serves 28 distinct federal customer agencies across life sciences, conservation, and agricultural research missions, with work concentrated under primary NAICS category 334516 (Analytical Laboratory Instrument Manufacturing, 81 awards) and PSC Laboratory Equipment and Supplies (74 awards).

Activity has remained flat over the past five years — six awards annually in 2022 and 2023, six in 2024, one in 2025, and two in 2026 — with only two awards totaling $62 thousand facing completion inside the next twenty-four months. Representative prime work includes a $149 thousand DNA extraction system purchase order from the U.S. Geological Survey (August 2024) supporting the Eastern Ecological Science Center's invasive species detection framework, a $115 thousand Flex Star instrument delivery to the National Heart, Lung and Blood Institute (November 2023), and recurring extended service agreements with NHGRI for the AutoGen Flex STARR at serial number 485017 running annually from 2022 through 2027 (most recent $22 thousand agreement, April 2026). Recent maintenance contracts include $39 thousand preventive maintenance for the National Institute of Allergy and Infectious Diseases' automated DNA isolation machine (March 2026) and $24 thousand for the AUTOGEN XTRACT 16+ delivery to the National Institute on Deafness and Other Communication Disorders (May 2025). Autogen acts as a sub-recipient on a single federal grant sub-award under the University of South Florida's Environmental Determinants of Diabetes in the Young Study (August 2024), representing less than 1% of its award footprint.

AutoGen provides expert DNA/RNA extraction solutions for labs, including outsourced processing services, highly automated instruments, and kits.

Workflows: Our instrumentation and consumables are configured to yield the greatest amount of usable nucleic acid. AutoGen workflows include Magnetic Bead-Based Isolation; Column-Based Isolation, and Precipitation-Based Isolation.

Extraction Services: Looking for a customized and flexible extraction provider? Access the latest in automated extraction equipment, chemistries, and protocols from a team of US-based extraction experts dedicated to your project's success.

Sample Storage, ID, and Handling: We have a wide selection of 2D barcoded tubes, barcode readers, de-capping, capping,that help labs better manage their samples, reduce handling times, and avoid costly misidentification errors.

Saliva & Microbiome Collection: AutoGen is the U.S. partner for Isohelix products, including DNA & RNA saliva collection devices.