Carl Zeiss Lattice SIM 5 laser scanning structured illumination super-resolution light microscope and Associated Supplies
Closed Solicitation Posted
This opportunity was awarded. See the award notice from .
- Solicitation number
- 75N98026Q00070
- Agency
-
Office of the Assistant Secretary for Administration
Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 334516 Analytical Laboratory Instrument Manufacturing
- PSC
- 6640 Laboratory Equipment And Supplies
- Place of performance
- Bethesda, Maryland, United States
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
The National Institutes of Health, National Cancer Institute (NCI), Center for Cancer Research is procuring one new Carl Zeiss Lattice SIM5 laser scanning structured illumination super-resolution light microscope with associated supplies and equipment for the CCR Microscopy Core. This non-competitive acquisition will be awarded directly to Carl Zeiss Microscope, LLC as the original equipment manufacturer, with the government intending to make the award without full and open competition under simplified acquisition procedures for commercial items. The complete system includes a Lattice SIM5 illumination module, Zeiss AxioObserver 7 inverted microscope, multiple objective lenses, Hamamatsu ORCA Fusion BT sCMOS cameras, four fiber-coupled lasers, stage-top incubation system, system air table with vibration control, two premium microscopy workstations, and ZEISS ZEN software licenses along with associated hardware and accessories. The solicitation requires the contractor to deliver and install all equipment within six months of order receipt with FOB Destination and inside delivery, provide training within two weeks of installation by a factory-trained product specialist for up to 10 users, include a minimum 12-month manufacturer's warranty and maintenance support services, and submit responses by April 22, 2026 at 10:00 a.m. Eastern Standard Time. Questions must be submitted by March 31, 2026, and offerors must provide clear evidence of capability, a Unique Entity Identifier, DUNS number, Tax Identification Number, business size certification, and active System for Award Management registration.
There is no small business set-aside on this procurement, as Amendment 2 removed the inadvertently included FAR clause 52.219-6 and all associated small business set-aside provisions effective April 2, 2026. The solicitation identifies Carl Zeiss Microscope, LLC as the intended non-competitive awardee with no incumbent contractor. The estimated equipment value exceeds $730,000, triggering Trade Agreements Act applicability, with equipment manufactured in Germany qualifying as TAA-compliant under FAR 25.402(a)(1) because Germany is a designated country. The contractor must deliver the complete microscope system, which comprises 81 itemized components including the base microscope unit, illumination modules, cameras, laser systems, objective lenses, control systems, software licenses, and two premium microscopy workstations, all within six months of award. The place of performance is the National Institutes of Health Main Campus, National Cancer Institute, Building 37, Room B114A, Bethesda, Maryland, with all shipping, handling, delivery, installation, and training expenses required to be included in the quoted price.
Notice text
2 versions
Update #2 · Latest ·
The purpose of Amendment 2 (two) is to omit clause FAR 52.219-6 that was inadvertently included in Amendment 1 (one) from the solicitation and to remove any associated small business set-aside provisions. All other terms and conditions remain unchanged. Please see Attachment 9 - Amendment 0002 and Attachment 2 – Terms and Conditions_revised.
Attachment 8 - AMENDMENT 1 Q&A - is attached. This amendment addresses questions and answers related to this solicitation.
The U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Cancer Institute (NCI) Center for Cancer Research (CCR), Laboratory of Cancer Biology and Genetics (LCBG), CCR Microscopy Core requires one (1) new, commercially available, Zeiss Lattice SIM5 super-resolution light microscope.
The National Cancer Institute is the principal federal agency for cancer research and training. It leads, conducts, and supports cancer research to advance scientific knowledge and improve cancer prevention, detection, diagnosis, and survivorship. The Center for Cancer Research (CCR) is the largest division of the NCI’s intramural research program with both basic and clinical research groups exploring the cutting edge of cancer research involving a wide spectrum of biological and biomedical problems that range from visualizing and understanding the structure of genes and proteins and developing novel assays to detect and potentially treat patients. The CCR Microscopy Core, the main microscopy core in the CCR, serves the imaging needs of a wide range of NCI researchers studying the cell biology of cancer. The core facility has five high-quality research-grade instruments, including confocal, multi-photon and super-resolution microscopes, to apply to the numerous research projects from the over 45 labs/branches within NCI, that use the Core annually. To satisfy the demands for super-resolution fluorescence microscopy, the CCR Microscopy Core requests a new Zeiss Lattice SIM5 structured illumination super-resolution microscope. Structured illumination super-resolution microscopy is an established method for acquiring high resolution images of biological samples and is in high demand from NCI researchers. The demand arises from the need to understand the molecular interactions of cellular proteins and the gene expression profiles of tumor cells. Super-resolution microscopy provides researchers the ability to visualize these molecular interactions within cells, and the newest SIM technology available from the requested Zeiss Latice SIM5 microscope will allow researchers to image these interactions in live cells. Thus, providing this cutting-edge technology to NCI researchers to apply to their cancer research projects and further improve our understanding of the cell biology of cancer.
The CCR Microscopy Core requires a new Zeiss Lattice SIM5 super-resolution microscope that shall include a high-speed lattice SIM5 scanner, dual high-sensitivity sCMOS cameras with Duolink configuration for simultaneous 2 channel imaging, four high-power lasers (wavelengths 405, 488, 561 and 647 nm), 500 um Piezo stage, stage-top incubation for live cell imaging, and both high numerical aperture oil and water immersion objective lenses for super-resolution imaging. Thus, it provides extended capabilities to image complex samples but also has the capability to perform functional live cell SIM imaging on larger biological samples. All users of the CCR Microscopy Core interested in performing SIM super-resolution microscopy will benefit from the requested Zeiss Lattice SIM5 microscope.
Update #1 ·
The U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Cancer Institute (NCI) Center for Cancer Research (CCR), Laboratory of Cancer Biology and Genetics (LCBG), CCR Microscopy Core requires one (1) new, commercially available, Zeiss Lattice SIM5 super-resolution light microscope.
The National Cancer Institute is the principal federal agency for cancer research and training. It leads, conducts, and supports cancer research to advance scientific knowledge and improve cancer prevention, detection, diagnosis, and survivorship. The Center for Cancer Research (CCR) is the largest division of the NCI’s intramural research program with both basic and clinical research groups exploring the cutting edge of cancer research involving a wide spectrum of biological and biomedical problems that range from visualizing and understanding the structure of genes and proteins and developing novel assays to detect and potentially treat patients. The CCR Microscopy Core, the main microscopy core in the CCR, serves the imaging needs of a wide range of NCI researchers studying the cell biology of cancer. The core facility has five high-quality research-grade instruments, including confocal, multi-photon and super-resolution microscopes, to apply to the numerous research projects from the over 45 labs/branches within NCI, that use the Core annually. To satisfy the demands for super-resolution fluorescence microscopy, the CCR Microscopy Core requests a new Zeiss Lattice SIM5 structured illumination super-resolution microscope. Structured illumination super-resolution microscopy is an established method for acquiring high resolution images of biological samples and is in high demand from NCI researchers. The demand arises from the need to understand the molecular interactions of cellular proteins and the gene expression profiles of tumor cells. Super-resolution microscopy provides researchers the ability to visualize these molecular interactions within cells, and the newest SIM technology available from the requested Zeiss Latice SIM5 microscope will allow researchers to image these interactions in live cells. Thus, providing this cutting-edge technology to NCI researchers to apply to their cancer research projects and further improve our understanding of the cell biology of cancer.
The CCR Microscopy Core requires a new Zeiss Lattice SIM5 super-resolution microscope that shall include a high-speed lattice SIM5 scanner, dual high-sensitivity sCMOS cameras with Duolink configuration for simultaneous 2 channel imaging, four high-power lasers (wavelengths 405, 488, 561 and 647 nm), 500 um Piezo stage, stage-top incubation for live cell imaging, and both high numerical aperture oil and water immersion objective lenses for super-resolution imaging. Thus, it provides extended capabilities to image complex samples but also has the capability to perform functional live cell SIM imaging on larger biological samples. All users of the CCR Microscopy Core interested in performing SIM super-resolution microscopy will benefit from the requested Zeiss Lattice SIM5 microscope.
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Notice history
| Notice | Type | Posted |
|---|---|---|
| Carl Zeiss Lattice SIM 5 laser scanning structured illumination super-resolution light microscope and Associated Supplies | Award Notice | |
| This notice | Solicitation |
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