Attachment 006 Batch 2 SDSs.pdf

Safety Data Sheet

Hydrogen Peroxide, 30% Page 1 of 4

Hydrogen Peroxide, 30%

Section 1 Product Description

Product Name: Hydrogen Peroxide, 30% Recommended Use: Science education applications Synonyms: Hydrogen Peroxide Solution Distributor: Carolina Biological Supply Company

2700 York Road, Burlington, NC 27215 1-800-227-1150

Chemical Information: 800-227-1150 (8am-5pm (ET) M-F) Chemtrec: 800-424-9300 (Transportation Spill Response 24 hours)

Section 2 Hazard Identification

Classification of the chemical in accordance with paragraph (d) of §1910.1200;

DANGER

May cause fire or explosion; strong oxidizer. Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage. Harmful to aquatic life. Harmful to aquatic life with long lasting effects.

GHS Classification:

Oxidizing Liquid Category 1, Skin Corrosion/Irritation Category 1A, Serious Eye Damage/Eye Irritation Category 1, Hazardous to the aquatic environment - Acute Category 3, Hazardous to the aquatic environment - Chronic Category 3, Acute Toxicity - Oral Category 4

Other Safety Precautions: In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.

Section 3 Composition / Information on Ingredients

Chemical Name CAS # % Water 7732-18-5 70 Hydrogen Peroxide 7722-84-1 30

Section 4 First Aid Measures

Emergency and First Aid Procedures Inhalation: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Eyes: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Skin Contact: IF ON CLOTHING: rinse immediately contaminated clothing and skin with plenty of water before removing clothes. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash contaminated clothing before reuse.

Ingestion: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF SWALLOWED: rinse mouth. Do NOT induce vomiting.

Section 5 Firefighting Procedures

Extinguishing Media: Use dry chemical, CO2 or appropriate foam.

Fire Fighting Methods and Protection: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus.

Hydrogen Peroxide, 30% Page 2 of 4

Fire and/or Explosion Hazards: Contact with combustible material may cause fire. Closed container may build up pressure if exposed to fire or heat.

Hazardous Combustion Products: Carbon dioxide, Carbon monoxide

Section 6 Spill or Leak Procedures

Prevent the spread of any spill to minimize harm to human health and the environment if safe to do so. Wear complete and proper personal protective equipment following the recommendation of Section 8 at a minimum. Dike with suitable absorbent material like granulated clay. Gather and store in a sealed container pending a waste disposal evaluation.

Section 7 Handling and Storage

Handling: Keep away from heat/sparks/open flames/hot surfaces. – No smoking. Keep/Store away from clothing/…/combustible materials. Take any precaution to avoid mixing with combustibles. Do not breathe dust/fume/gas/mist/vapors/spray. Wash thoroughly after handling. Do no eat, drink or smoke when using this product. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. Wear fire/flame resistant/retardant clothing. Avoid contact with skin and eyes. Do not ingest or take internally. Keep away from combustible material.

Storage: Store locked up. Avoid direct sunlight and heat.

Store in a secure area suitable for oxidizing agents. Store away from flammable materials, organic solvents and combustible materials.

Storage Code: Yellow - Reactive. Store separate and away from incompatible material.

Section 8 Protection Information

ACGIH OSHA PEL

Chemical Name (TWA) (STEL) (TWA) (STEL) Hydrogen Peroxide 1 ppm TWA N/A 1 ppm TWA; 1.4 mg/m3 TWA N/A

Control Parameters Engineering Measures: No exposure limits exist for the constituents of this product. General room ventilation might be required to maintain operator comfort under normal conditions of use.

Personal Protective Equipment (PPE): Lab coat, apron, eye wash, safety shower.

Respiratory Protection: No respiratory protection required under normal conditions of use.

Eye Protection: Wear chemical splash goggles when handling this product. Have an eye wash station available.

Skin Protection: Avoid skin contact by wearing chemically resistant gloves, an apron and other protective equipment depending upon conditions of use. Inspect gloves for chemical break-through and replace at regular intervals. Clean protective equipment regularly. Wash hands and other exposed areas with mild soap and water before eating, drinking, and when leaving work.

Gloves: No information available

Section 9 Physical Data

Formula: H202 (aq) Vapor Pressure: 24 mmHg at 20°C Molecular Weight: 34.01 Evaporation Rate (BuAc=1): <= 1 (BuAc) Appearance: Colorless Vapor Density (Air=1): 1.17 Odor: None Specific Gravity: 1.1 Odor Threshold: No data available Solubility in Water: Soluble pH: No data available Log Pow (calculated): No data available Melting Point: No data available Autoignition Temperature: No data available Boiling Point: 100 C Decomposition Temperature: No data available Flash Point: No data available Viscosity: No data available Flammable Limits in Air: N/A Percent Volatile by Volume: N/A

Section 10 Reactivity Data

Reactivity: No data available Chemical Stability: Stable under normal conditions.

Conditions to Avoid: Elevated temperatures

Hydrogen Peroxide, 30% Page 3 of 4

Incompatible Materials: Water-reactive materials, Reducing agents,, Copper alloys, Acids, contact with flammable materials

Hazardous Polymerization: Will not occur

Section 11 Toxicity Data

Routes of Entry Inhalation, ingestion, eye or skin contact.

Symptoms (Acute):

Delayed Effects: No data available

Acute Toxicity:

Chemical Name CAS Number Oral LD50 Dermal LD50 Inhalation LC50 Water 7732-18-5 Oral LD50 Rat

90000 mg/kg Hydrogen Peroxide 7722-84-1 Oral LD50 Rat 376 mg/kg Dermal LD50 Rat 4060 mg/kg

INHALATION

LC50 Rat 2

GM/M3

Carcinogenicity:

Chemical Name CAS Number IARC NTP OSHA

No data available 7732-18-5 7722-84-1

Not listed Not listed Not listed

Chronic Effects:

Mutagenicity: No evidence of a mutagenic effect.

Teratogenicity: No evidence of a teratogenic effect (birth defect).

Sensitization: No evidence of a sensitization effect.

Reproductive: No evidence of negative reproductive effects.

Target Organ Effects:

Acute: See Section 2 Chronic: Not listed as a carcinogen by IARC, NTP or OSHA., Mutation data cited.

Section 12 Ecological Data

Overview: This material is not expected to be harmful to the ecology.

Mobility: No data Persistence: No data Bioaccumulation: No data Degradability: No data Other Adverse Effects: No data

Chemical Name CAS Number Eco Toxicity Water 7732-18-5 No data available Hydrogen Peroxide 7722-84-1 96 HR LC50 PIMEPHALES PROMELAS 16.4 MG/L

24 HR EC50 DAPHNIA MAGNA 7.7 MG/L

72 HR EC50 CHLORELLA VULGARIS 2.5 MG/L

Section 13 Disposal Information

Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations. Always contact a permitted waste disposer (TSD) to assure compliance.

Waste Disposal Code(s): Not Determined

Section 14 Transport Information

Ground - DOT Proper Shipping Name: Air - IATA Proper Shipping Name:

UN2014

HYDROGEN PEROXIDE, AQUEOUS SOLUTION

Division 5.1 (8)

P.G. II

UN number: 2014 Class: 5.1 (8) Packing group: II Proper shipping name: Hydrogen peroxide, aqueous solution

Hydrogen Peroxide, 30% Page 4 of 4

Section 15 Regulatory Information

TSCA Status: All components in this product are on the TSCA Inventory.

Chemical Name CAS Number

§ 313 Name § 304 RQ CERCLA RQ § 302 TPQ CAA 112(2)

TQ

Hydrogen Peroxide 7722-84-1 No No No 1000 lb TPQ (concentratio n >52%)

No

California Prop 65: No California Proposition 65 ingredients

Section 16 Additional Information

Revised: 08/21/2018 Replaces: 06/15/2018 Printed: 08-25-2018

The information provided in this (Material) Safety Data Sheet represents a compilation of data drawn directly from various sources available to us. Carolina Biological Supply makes no representation or guarantee as to the suitability of this information to a particular application of the substance covered in the (Material) Safety Data Sheet.

Glossary

ACGIH

CAS

CERCLA

DOT

IARC

N/A

American Conference of Governmental Industrial Hygienists Chemical Abstract Service Number Comprehensive Environmental Response, Compensation, and Liability Act U.S. Department of Transportation International Agency for Research on Cancer Not Available

NTP

OSHA

PEL

ppm

RCRA

SARA

TLV

TSCA

IDLH

National Toxicology Program Occupational Safety and Health Administration Permissible Exposure Limit Parts per million Resource Conservation and Recovery Act Superfund Amendments and Reauthorization Act Threshold Limit Value Toxic Substances Control Act Immediately dangerous to life and health

Horseradish Peroxidase

Horse radish peroxidase; Horseradish peroxidase

Powder.

CHEMTREC: 800.424.9300

Outside US: 703.527.3887

SAFETY DATA SHEET

GHS product identifier

Other means of identification

Product type

Emergency telephone number (with hours of operation)

Section 1. Identification

Chemical name : Peroxidase

Supplier's details : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States

815.968.0747 or 800.874.3723 7 AM - 5 PM Central Time (GMT -06:00)

Horseradish Peroxidase

Relevant identified uses of the substance or mixture and uses advised against

Not applicable.

Product code

SDS #

CAS #

Chemical formula

0031490 0031491 0031491B 1856273 1885360

Not available.

9003-99-0

Section 2. Hazards identification

Not classified.Classification of the substance or mixture

Signal word : No signal word.

Hazard statements : No known significant effects or critical hazards.

Precautionary statements

Prevention : Not applicable.

Response : Not applicable.

Storage : Not applicable.

Disposal : Not applicable.

GHS label elements

OSHA/HCS status : While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

Hazards not otherwise classified

: Handling and/or processing of this material may generate a dust which can cause mechanical irritation of the eyes, skin, nose and throat.

Section 3. Composition/information on ingredients

Chemical name : Peroxidase

Other means of identification

: Horse radish peroxidase; Horseradish peroxidase

Substance/mixture

CAS number/other identifiers

: Substance

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 1/9

Section 3. Composition/information on ingredients

Peroxidase 98 - 100 9003-99-0

Ingredient name CAS number%

There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

CAS number : 9003-99-0

Occupational exposure limits, if available, are listed in Section 8.

Any concentration shown as a range is to protect confidentiality or is due to batch variation.

Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes.

Get medical attention if symptoms occur.

Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur.

Section 4. First aid measures

Eye contact

Skin contact

Inhalation

Ingestion :

Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.

Notes to physician : Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been ingested or inhaled.

Description of necessary first aid measures

Specific treatments : No specific treatment.

Most important symptoms/effects, acute and delayed

Inhalation : Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the nose, throat and lungs.

No known significant effects or critical hazards.:Ingestion

Skin contact : No known significant effects or critical hazards.

Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the eyes.

:Eye contact

Over-exposure signs/symptoms

Skin contact

Ingestion

Inhalation Adverse symptoms may include the following:

respiratory tract irritation coughing

No specific data.

No specific data.

Eye contact : Adverse symptoms may include the following:

irritation redness

Potential acute health effects

See toxicological information (Section 11)

Indication of immediate medical attention and special treatment needed, if necessary

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 2/9

Section 5. Fire-fighting measures

Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Hazardous thermal decomposition products

Specific hazards arising from the chemical

No specific data.

No specific fire or explosion hazard.

Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Special protective equipment for fire-fighters

Use an extinguishing agent suitable for the surrounding fire.

Extinguishing media

None known.

Suitable extinguishing media

Unsuitable extinguishing media

Special protective actions for fire-fighters

Section 6. Accidental release measures

Environmental precautions

Personal precautions, protective equipment and emergency procedures

Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Vacuum or sweep up material and place in a designated, labeled waste container. Avoid creating dusty conditions and prevent wind dispersal. Dispose of via a licensed waste disposal contractor. Note: see Section 1 for emergency contact information and Section 13 for waste disposal.

: No action shall be taken involving any personal risk or without suitable training.

Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing dust. Put on appropriate personal protective equipment.

Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air).

Large spill :

Move containers from spill area. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor.

Small spill :

Methods and materials for containment and cleaning up

For non-emergency personnel

For emergency responders : If specialised clothing is required to deal with the spillage, take note of any information in Section 8 on suitable and unsuitable materials. See also the information in "For non-emergency personnel".

Section 7. Handling and storage

Advice on general occupational hygiene

Conditions for safe storage, including any incompatibilities

Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Do not store above the following temperature: -20°C (-4°F). Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Protective measures Put on appropriate personal protective equipment (see Section 8). Avoid breathing dust.:

Precautions for safe handling

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 3/9

None.

Section 8. Exposure controls/personal protection

Hand protection

Use a properly fitted, particulate filter respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.

Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary.

Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. If contact is possible, the following protection should be worn, unless the assessment indicates a higher degree of protection: safety glasses with side-shields. If operating conditions cause high dust concentrations to be produced, use dust goggles.

Eye/face protection

Respiratory protection :

Body protection Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

Environmental exposure controls

: Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Appropriate engineering controls

: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor or mist, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits.

Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Hygiene measures :

Control parameters

Individual protection measures

Occupational exposure limits

Skin protection

Other skin protection : Appropriate footwear and any additional skin protection measures should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

Section 9. Physical and chemical properties

Physical state

Melting point

Solid. [Crystalline powder.]

Not available.

Odorless.Odor pH

Off-white. Beige. Brown.Color

Evaporation rate Not available.

Flash point [Product does not sustain combustion.]

Not available.

Not available.Odor threshold

Appearance

Boiling point : Not available.

Flammability (solid, gas) : No results available.

Lower and upper explosive (flammable) limits

: Not available.

Burning rate Not available.:

Burning time : Not available.

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 4/9

Section 9. Physical and chemical properties Vapor pressure

Relative density

Vapor density

Solubility

Not available.

Not available.

Not available.

Soluble in the following materials: cold water and hot water.

Auto-ignition temperature Not available.

Not available.

Viscosity Not available.

Partition coefficient: n-octanol/water

SADT Not available.:

Decomposition temperature : Not available.

Solubility in water : 0.5 g/l

Section 10. Stability and reactivity

Hazardous decomposition products

Conditions to avoid No specific data.

Under normal conditions of storage and use, hazardous decomposition products should not be produced.

The product is stable.Chemical stability

No specific data.

Incompatible materials :

Possibility of hazardous reactions

: Under normal conditions of storage and use, hazardous reactions will not occur.

Reactivity : No specific test data related to reactivity available for this product or its ingredients.

Section 11. Toxicological information

Acute toxicity

Not available.

Conclusion/Summary : To the best of our knowledge, the toxicological properties of this substance have not been thoroughly investigated.

Carcinogenicity

Not available.

Mutagenicity

Not available.

Teratogenicity

Not available.

Reproductive toxicity

Not available.

Irritation/Corrosion

Not available.

Sensitization

Not available.

Specific target organ toxicity (single exposure)

Specific target organ toxicity (repeated exposure)

Not available.

Information on toxicological effects

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 5/9

Section 11. Toxicological information

Not available.

Conclusion/Summary : May cause allergic reactions in certain individuals.

Information on the likely routes of exposure

Inhalation : Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the nose, throat and lungs.

No known significant effects or critical hazards.:Ingestion

Skin contact : No known significant effects or critical hazards.

Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the eyes.

:Eye contact

Repeated or prolonged inhalation of dust may lead to chronic respiratory irritation.General :

No known significant effects or critical hazards.Carcinogenicity :

No known significant effects or critical hazards.Mutagenicity :

No known significant effects or critical hazards.Teratogenicity :

Developmental effects : No known significant effects or critical hazards.

Fertility effects : No known significant effects or critical hazards.

Symptoms related to the physical, chemical and toxicological characteristics

Skin contact

Ingestion

Inhalation Adverse symptoms may include the following:

respiratory tract irritation coughing

No specific data.

No specific data.

Eye contact : Adverse symptoms may include the following:

irritation redness

Potential chronic health effects

Delayed and immediate effects and also chronic effects from short and long term exposure

Not available.

Numerical measures of toxicity

Not available.

Acute toxicity estimates

Aspiration hazard

Not available.

: Routes of entry anticipated: Oral, Inhalation.

Potential acute health effects

Potential immediate effects

: Not available.

Short term exposure

Potential delayed effects : Not available.

Potential immediate effects

: Not available.

Long term exposure

Potential delayed effects : Not available.

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 6/9

Section 12. Ecological information

Bioaccumulative potential

Other adverse effects : No known significant effects or critical hazards.

Not available.

Product/ingredient name Aquatic half-life Photolysis Biodegradability

Peroxidase - - Readily

Toxicity

Not available.

Persistence and degradability

Soil/water partition coefficient (KOC)

: Not available.

Mobility in soil

Section 13. Disposal considerations The generation of waste should be avoided or minimized wherever possible. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Waste should not be disposed of untreated to the sewer unless fully compliant with the requirements of all authorities with jurisdiction.

Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible. This material and its container must be disposed of in a safe way. Empty containers or liners may retain some product residues. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

:Disposal methods

Section 14. Transport information

Not regulated.

Not regulated.

DOT Classification IATA

UN number

UN proper shipping name

Transport hazard class(es)

Packing group

Additional information

Environmental hazards

Special precautions for user

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

No. No.

Transport within user’s premises: always transport in closed containers that are upright and secure. Ensure that persons transporting the product know what to do in the event of an accident or spillage.

: Not available.

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 7/9

Section 15. Regulatory information U.S. Federal regulations

This material is not listed.Massachusetts

Clean Air Act Section 112

(b) Hazardous Air Pollutants (HAPs)

: Not listed

Clean Air Act Section 602 Class I Substances

: Not listed

Clean Air Act Section 602 Class II Substances

: Not listed

DEA List I Chemicals (Precursor Chemicals)

: Not listed

DEA List II Chemicals (Essential Chemicals)

: Not listed

New York : This material is not listed.

New Jersey : This material is not listed.

Pennsylvania : This material is not listed.

State regulations

TSCA 8(a) CDR Exempt/Partial exemption: This material is listed or exempted.

United States inventory (TSCA 8b): This material is listed or exempted.

SARA 302/304

SARA 304 RQ : Not applicable.

No products were found.

Composition/information on ingredients

SARA 311/312

Classification : Not applicable.

No products were found.

Composition/information on ingredients

Canada inventory : This material is listed or exempted.

Australia inventory (AICS): This material is listed or exempted.

China inventory (IECSC): This material is listed or exempted.

Japan inventory: Not determined.

Korea inventory: This material is listed or exempted.

Malaysia Inventory (EHS Register): Not determined.

New Zealand Inventory of Chemicals (NZIoC): This material is listed or exempted.

Philippines inventory (PICCS): Not determined.

Taiwan inventory (CSNN): Not determined.

International regulations

International lists :

Chemical Weapons Convention List Schedule I Chemicals

: Not listed

Chemical Weapons Convention List Schedule II Chemicals

: Not listed

Chemical Weapons Convention List Schedule III Chemicals

: Not listed

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 8/9

Section 16. Other information

12/12/2013.

History

Date of printing

Date of issue/Date of revision

Version

To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein.

Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

Notice to reader

Date of previous issue

Indicates information that has changed from previously issued version.

References : Not available.

Key to abbreviations : ATE = Acute Toxicity Estimate BCF = Bioconcentration Factor GHS = Globally Harmonized System of Classification and Labelling of Chemicals IATA = International Air Transport Association IBC = Intermediate Bulk Container IMDG = International Maritime Dangerous Goods LogPow = logarithm of the octanol/water partition coefficient MARPOL 73/78 = International Convention for the Prevention of Pollution From Ships, 1973 as modified by the Protocol of 1978. ("Marpol" = marine pollution) UN = United Nations

8/22/2013.

No previous validation.

Hazardous Material Information System (U.S.A.)

National Fire Protection Association (U.S.A.)

Health

Special

Instability/Reactivity

Flammability

Health

Flammability

Caution: HMIS® ratings are based on a 0-4 rating scale, with 0 representing minimal hazards or risks, and 4 representing significant hazards or risks Although HMIS® ratings are not required on SDSs under 29 CFR 1910.

1200, the preparer may choose to provide them. HMIS® ratings are to be used with a fully implemented HMIS® program. HMIS® is a registered mark of the National Paint & Coatings Association (NPCA). HMIS® materials may be purchased exclusively from J. J. Keller (800) 327-6868.

The customer is responsible for determining the PPE code for this material.

Reprinted with permission from NFPA 704-2001, Identification of the Hazards of Materials for Emergency Response Copyright ©1997, National Fire Protection Association, Quincy, MA 02269. This reprinted material is not the complete and official position of the National Fire Protection Association, on the referenced subject which is represented only by the standard in its entirety.

Copyright ©2001, National Fire Protection Association, Quincy, MA 02269. This warning system is intended to be interpreted and applied only by properly trained individuals to identify fire, health and reactivity hazards of chemicals. The user is referred to certain limited number of chemicals with recommended classifications in NFPA 49 and NFPA 325, which would be used as a guideline only. Whether the chemicals are classified by NFPA or not, anyone using the 704 systems to classify chemicals does so at their own risk.

Physical hazards

Chronic Health Hazard

SDS SpecialistPrepared by :

Date of issue/Date of revision : 8/22/2013. Date of previous issue : No previous validation. Version : 1 9/9

Sigma - I5386

The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the US and Canada

SAFETY DATA SHEET

Version 6.9 Revision Date 04/28/2025

Print Date 04/29/2025

SECTION 1. IDENTIFICATION

1.1 Product identifiers

Product name : Indole-3-butyric acid

Product Number : I5386

Brand : Sigma

CAS-No. : 133-32-4

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses : Laboratory chemicals, Synthesis of substances

Uses advised against : The product is being supplied under the TSCA R&D Exemption

(40 CFR Section 720.36). It is the recipient’s responsibility to comply with the requirements of the R&D exemption. The product may not be used for a non-exempt commercial purpose under TSCA unless appropriate consent is granted in writing by

MilliporeSigma.

1.3 Details of the supplier of the safety data sheet

Company : Sigma-Aldrich Inc.

3050 SPRUCE ST

ST. LOUIS MO 63103

UNITED STATES

Telephone : +1 314 771-5765

Fax : +1 800 325-5052

1.4 Emergency telephone

Emergency Phone # : 800-424-9300 CHEMTREC (USA) +1-703-

527-3887 CHEMTREC (International) 24

Hours/day; 7 Days/week

SECTION 2. HAZARDS IDENTIFICATION

GHS classification in accordance with the OSHA Hazard Communication Standard

(29 CFR 1910.1200)

Acute toxicity (Oral)

: Category 3

Other hazards

None known.

GHS label elements

Hazard pictograms

Signal Word

: Danger

Hazard Statements

: H301 Toxic if swallowed.

Precautionary Statements

Prevention:

P264 Wash skin thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

Response:

P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth.

Storage:

P405 Store locked up.

Disposal:

P501 Dispose of contents/ container to an approved waste disposal plant.

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS

Substance / Mixture

: Substance

Components

Chemical name CAS

No./Unique ID

Concentration (% w/w) Trade secret indole-3-butyric acid 133-32-4* >= 90 - <= 100 -

* Indicates that the identifier is a CAS No.

Actual concentration is withheld as a trade secret

SECTION 4. FIRST AID MEASURES

General advice

: Show this material safety data sheet to the doctor in attendance.

If inhaled

: After inhalation: fresh air.

In case of skin contact

: In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

: After eye contact: rinse out with plenty of water.

Remove contact lenses.

If swallowed

: If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.

Most important symptoms and effects, both acute and delayed

: The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Protection of first-aiders

: For personal protection see section 8.

Notes to physician

: No data available

SECTION 5. FIRE-FIGHTING MEASURES

Suitable extinguishing media

: Water

Foam

Carbon dioxide (CO2)

Dry powder

Unsuitable extinguishing media

: For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards during fire fighting

: Combustible.

Development of hazardous combustion gases or vapours possible in the event of fire.

Hazardous combustion products

: Carbon oxides

Nitrogen oxides (NOx)

Specific extinguishing methods

Further information

: Suppress (knock down) gases/vapors/mists with a water spray jet.

Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipment for fire-fighters

: Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

SECTION 6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

: Advice for non-emergency personnel:

Avoid inhalation of dusts.

Avoid substance contact.

Ensure adequate ventilation.

Evacuate the danger area, observe emergency procedures, consult an expert.

Advice for emergency responders:

For personal protection see section 8.

Environmental precautions

: Do not let product enter drains.

Methods and materials for containment and cleaning up

: Cover drains. Collect, bind, and pump off spills.

Observe possible material restrictions (see sections 7 and 10).

Take up carefully. Dispose of properly. Clean up affected area.

Avoid generation of dusts.

SECTION 7. HANDLING AND STORAGE

For precautions see section 2.2.

Further information on storage conditions

: Tightly closed.

Dry.

Keep in a well-ventilated place.

Keep locked up or in an area accessible only to qualified or authorized persons.

Storage class

: 6.1C, Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Recommended storage temperature

: 36 - 46 °F / 2 - 8 °C

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

Engineering measures : No data available

Personal protective equipment

Respiratory protection

: required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN

EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type:

: Filter type P3

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.

Hand protection

Material : Nitrile rubber

Break through time : 480 min

Glove thickness : 0.11 mm

Protective index : Full contact

Manufacturer : KCL 741 Dermatril® L

Material : Nitrile rubber

Break through time : 480 min

Glove thickness : 0.11 mm

Protective index : Splash contact

Manufacturer : KCL 741 Dermatril® L

Remarks

: This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-

36124 Eichenzell, Internet: www.kcl.de).

Eye protection

: Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Safety glasses

Skin and body protection

: protective clothing

Hygiene measures

: Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance

: solid

Color

Odor

Odor Threshold : No data available pH

Melting point

: 250 - 259 °F / 121 - 126 °C

Boiling point/boiling range

Flash point

Evaporation rate

Flammability (solid, gas)

Flammability (liquids)

Burning rate

Upper explosion limit /

Upper flammability limit

Lower explosion limit /

Lower flammability limit

Vapor pressure

Relative vapor density

Relative density

Density

Solubility(ies)

Water solubility : 0.25 g/l (68 °F / 20 °C)

Partition coefficient: n-octanol/water

: log Pow: 2.30

Method: (experimental)

Bioaccumulation is not expected.

Autoignition temperature

Decomposition temperature

Viscosity, dynamic

Viscosity, kinematic

Flow time

Explosive properties

Oxidizing properties

: none

Molecular weight

: 203.24 g/mol

Particle characteristics

Particle size

SECTION 10. STABILITY AND REACTIVITY

Reactivity

: The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability

: The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

: Violent reactions possible with:

Strong oxidizing agents strong alkalis

Conditions to avoid

: no information available

Incompatible materials

Hazardous decomposition products

: In the event of fire: see section 5

SECTION 11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects

Acute toxicity

LD50 Oral - Mouse - 100 mg/kg

Remarks: (RTECS)

Inhalation: No data available

Dermal: No data available

Skin corrosion/irritation

No data available

Serious eye damage/eye irritation

No data available

Respiratory or skin sensitization

No data available

Germ cell mutagenicity

Test Type: Ames test

Test system: Salmonella typhimurium

Metabolic activation: with and without metabolic activation

Result: negative

Remarks: (Lit.)

Carcinogenicity

IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

NTP: No ingredient of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.

OSHA: No component of this product present at levels greater than or equal to 0.1% is on OSHA’s list of regulated carcinogens.

Reproductive toxicity

No data available

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

11.2 Additional Information

RTECS: NL5250000

To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

After absorption:

We have no description of any toxic symptoms.

Other dangerous properties can not be excluded.

Handle in accordance with good industrial hygiene and safety practice.

SECTION 12. ECOLOGICAL INFORMATION

Ecotoxicity

No data available

Persistence and degradability

Components:

indole-3-butyric acid:

Biodegradability

: Result: Readily biodegradable.

Bioaccumulative potential

Components:

indole-3-butyric acid:

Partition coefficient: n-octanol/water

: log Pow: 2.30

Method: (experimental)

Remarks: Bioaccumulation is not expected.

Mobility in soil

No data available

Other adverse effects

No data available

SECTION 13. DISPOSAL CONSIDERATIONS

Disposal methods

Waste from residues : Waste material must be disposed of in accordance with the national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.

SECTION 14. TRANSPORT INFORMATION

International Regulations

IATA-DGR

UN/ID No. : UN 2811

Proper shipping name : Toxic solid, organic, n.o.s.

(indole-3-butyric acid)

Class : 6.1

Packing group : III

Labels : Division 6.1 - Toxic substances

Packing instruction (cargo aircraft)

: 677

Packing instruction

(passenger aircraft)

: 670

IMDG-Code

UN number : UN 2811

Proper shipping name : TOXIC SOLID, ORGANIC, N.O.S.

(indole-3-butyric acid)

Class : 6.1

Packing group : III

Labels : 6.1

EmS Code : F-A, S-A

Marine pollutant : no

Transport in bulk according to IMO instruments

Not applicable for product as supplied.

National regulation

49 CFR Road

UN/ID/NA number : UN 2811

Proper shipping name : Toxic solids, organic, n.o.s.

(indole-3-butyric acid)

Class : 6.1

Packing group : III

Labels : Division 6.1 - Toxic substances

ERG Code : 154

Marine pollutant : no

Poison Inhalation Hazard : No

Special precautions for user

The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety

Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.

SECTION 15. REGULATORY INFORMATION

CERCLA Reportable Quantity

This material does not contain any components with a CERCLA RQ.

SARA 304 Extremely Hazardous Substances Reportable Quantity

This material does not contain any components with a section 304 EHS RQ.

SARA 302 Extremely Hazardous Substances Threshold Planning Quantity

This material does not contain any components with a section 302 EHS TPQ.

SARA 311/312

Hazards

: Acute Health Hazard

SARA 313

: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by

SARA Title III, Section 313.

US State Regulations

Massachusetts Right To Know

No components are subject to the Massachusetts Right to Know Act.

Maine Chemicals of High Concern

Product does not contain any listed chemicals

Vermont Chemicals of High Concern

Product does not contain any listed chemicals

Washington Chemicals of High Concern

Product does not contain any listed chemicals

The ingredients of this product are reported in the following inventories:

TSCA

: All substances listed as active on the TSCA inventory

TSCA list

No substances are subject to a Significant New Use Rule.

No substances are subject to TSCA 12(b) export notification requirements.

SECTION 16. OTHER INFORMATION

Full text of other abbreviations

AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Testing of Materials; bw - Body weight; CERCLA - Comprehensive Environmental Response, Compensation, and Liability Act; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN -

Standard of the German Institute for Standardisation; DOT - Department of Transportation;

DSL - Domestic Substances List (Canada); ECx - Concentration associated with x% response;

EHS - Extremely Hazardous Substance; ELx - Loading rate associated with x% response;

EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx -

Concentration associated with x% growth rate response; ERG - Emergency Response Guide;

GHS - Globally Harmonized System; GLP - Good Laboratory Practice; HMIS - Hazardous

Materials Identification System; IARC - International Agency for Research on Cancer; IATA -

International Air Transport Association; IBC - International Code for the Construction and

Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing

Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO -

International Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO -

International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory;

LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships; MSHA - Mine Safety and Health Administration; n.o.s. - Not

Otherwise Specified; NFPA - National Fire Protection Association; NO(A)EC - No Observed

(Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No

Observable Effect Loading Rate; NTP - National Toxicology Program; NZIoC - New Zealand

Inventory of Chemicals; OECD - Organization for Economic Co-operation and Development;

OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and

Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; RCRA -

Resource Conservation and Recovery Act; REACH - Regulation (EC) No 1907/2006 of the

European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RQ - Reportable Quantity; SADT - Self-

Accelerating Decomposition Temperature; SARA - Superfund Amendments and

Reauthorization Act; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory;

TECI - Thailand Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United

States); UN - United Nations; UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative

The information is believed to be correct but is not exhaustive and will be used solely as a guideline, which is based on current knowledge of the chemical substance or mixture and is applicable to appropriate safety precautions for the product. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only.

Revision Date : 04/28/2025

The branding on the header and/or footer of this document may temporarily not visually match the product purchased as we transition our branding. However, all of the information in the document regarding the product remains unchanged and matches the product ordered.

For further information please contact mlsbranding@sial.com.

US / EN

1. Identification

Product identifier Imidacloprid

Other means of identification

Product code N-12206

Recommended use For Laboratory Use Only

Recommended restrictions None known.

Manufacturer/Importer/Supplier/Distributor information

Manufacturer

Chem Service, Inc.

Address 660 Tower Lane

Company name

Website

Telephone Toll Free 800-452-9994

Direct 610-692-3026

Emergency phone number Chemtrec US 800-424-9300

Chemtrec outside US +1 703-527-3887

E-mail

United States www.chemservice.com info@chemservice.com

West Chester, PA 19380

2. Hazard(s) identification

Not classified.Physical hazards

Category 4Acute toxicity, oralHealth hazards

Category 2Acute toxicity, inhalation

Category 1Hazardous to the aquatic environment, acute hazard

Environmental hazards

Category 1Hazardous to the aquatic environment, long-term hazard

Not classified.OSHA defined hazards

Label elements

Signal word Danger

Hazard statement Harmful if swallowed. Fatal if inhaled. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Precautionary statement

Prevention Use only outdoors or in a well-ventilated area. Do not breathe dust/fume. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Avoid release to the environment.

Wear respiratory protection.

Response If swallowed: Call a poison center/doctor if you feel unwell. If inhaled: Remove person to fresh air and keep comfortable for breathing. Immediately call a poison center/doctor. Specific treatment is urgent (see this label). Rinse mouth. Collect spillage.

Storage Store in a well-ventilated place. Keep container tightly closed. Store locked up.

Disposal Dispose of contents/container in accordance with local/regional/national/international regulations.

Hazard(s) not otherwise classified (HNOC) None known.

Supplemental information Not applicable.

3. Composition/information on ingredients

Substances

CAS number %Chemical name Common name and synonyms

138261-41-3Imidacloprid 100

1 / 7

Material name: Imidacloprid

13691 Version #: 01 Issue date: 05-06-2014

SDS US

*Designates that a specific chemical identity and/or percentage of composition has been withheld as a trade secret.

4. First-aid measures

Inhalation Remove victim to fresh air and keep at rest in a position comfortable for breathing. Oxygen or artificial respiration if needed. Do not use mouth-to-mouth method if victim inhaled the substance.

Induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Call a physician or poison control center immediately.

Skin contact Rinse with water. Get medical attention if irritation develops and persists.

Eye contact Do not rub eyes. Rinse with water. Get medical attention if irritation develops and persists.

Ingestion Rinse mouth. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Most important symptoms/effects, acute and delayed

Direct contact with eyes may cause temporary irritation.

Indication of immediate medical…