Signature Science LLC
Austin, TX Part of Southwest Research Institute
- UEI
- GMK2EG5EDNL7
- CAGE
- 1TE69
- SAM.gov registration
- Active through
Company facts
- FY2025 rankings
- Self-certified in SAM.gov
- Entity structure
- Partnership or Limited Liability Partnership
- Other NAICS codes in SAM.gov
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- 334516 Analytical Laboratory Instrument Manufacturing
- 541330 Engineering Services
- 541380 Testing Laboratories and Services
- 541420 Industrial Design Services
- 541511 Custom Computer Programming Services
- 541620 Environmental Consulting Services
- 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Corporate family
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Parent
Southwest Research Institute · San Antonio, TX
PB11V1KH3KV4
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- Signature Science, LLC · Charlottesville, VA MR3JB7VNYKL9
- Signature Science, LLC · Arlington, VA RQCDAH14XXL5
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Parent
Southwest Research Institute · San Antonio, TX
PB11V1KH3KV4
- SAM.gov registration date
- Physical address
- 8501 N Mopac Expy Suite 100, Austin, TX 78759, USA
- Website
- signaturescience.com
- Founded
- 2001
- Employees
- 251-1K
- Estimated annual revenue
- $10M-$50M
- Industry
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- Health Care
- Pharmaceuticals, Biotechnology & Life Sciences
- Biotechnology
- SIC code
- 87 Engineering & Management Services
- Profiles
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Contract obligations by fiscal year
| Fiscal year | Obligated |
|---|---|
| FY2027 To date | -$33,318 |
| FY2026 | $8,935,479 |
| FY2025 | $14,656,086 |
| FY2024 | $17,569,335 |
| FY2023 | $10,880,369 |
Top agencies by obligations
| Rank | Agency | Obligated, FY2026–FY2027 | Share |
|---|---|---|---|
| 1 | Department of Homeland Security | $3,813,935 | |
| 2 | Defense Finance and Accounting Service | $3,576,791 | |
| 3 | Defense Threat Reduction Agency | $862,696 | |
| 4 | Department of Justice | $626,078 | |
| 5 | Department of the Army | $22,662 |
Contract vehicles
- Environmental Services
- Joint Enterprise Research Development Acquisition and Production-Procurement
- Multiple Award Schedule
- One Acquisition Solution for Integrated Services Plus - Unrestricted
- The Professional Services Schedule
Expired vehicles (1)
Contract awards
| Award | Agency | Obligated | Awarded |
|---|---|---|---|
| Expert witness services | US Attorney's Offices (OBD) | $20,613 | |
| Expert witness services | US Attorney's Offices (OBD) | $21,273 | |
| Expert witness services | US Attorney's Offices (OBD) | $20,017 | |
| Expert witness services | US Attorney's Offices (OBD) | $20,613 | |
| Expert witness services | US Attorney's Offices (OBD) | $22,919 |
Latest 5 listed here. See the rest on GovTribe.
Contract subawards
| Prime contractor | Prime award | Amount | Awarded |
|---|---|---|---|
| Battelle Memorial Institute | FA807522F0003 | $32,000 | |
| Aktarius LLC | W911S721C0004 | $333,734 |
Grant awards
| Award | Agency | Obligated | Awarded |
|---|---|---|---|
| Gaming technologies for crisis response training | Office of Justice Programs | $477,891 |
Grant subawards
| Prime recipient | Prime award | Amount | Awarded |
|---|---|---|---|
| Council Of State And Territorial Epidemiologists, Inc. | NU38PW000005 | $124,646 |
Similar vendors
| Vendor | Location | Primary NAICS |
|---|---|---|
| JS Forensic Consulting LLC | Encinitas, CA | 541330 Engineering Services |
| Bode Technology | Lorton, VA | 541380 Testing Laboratories and Services |
| Vident Partners | Dallas, TX | 541199 All Other Legal Services |
| Biodynamic Research Corporation | San Antonio, TX | 813920 Professional Organizations |
| Forensic Medical Services Inc. | New Albany, IN | 621111 Offices of Physicians (except Mental Health Specialists) |
About the company
Signature Science LLC, a for-profit limited liability company and subsidiary of the nonprofit Southwest Research Institute, delivers forensic science and expert witness services to the U.S. Department of Justice and specialized research and threat-assessment support to the Department of Defense and Department of Homeland Security as a prime contractor, competing full-and-open without reliance on small business set-asides.
Signature Science's federal footprint is dominated by expert witness services to the U.S. Attorney's Offices, which account for 911 of its 1,097 awards (91% coverage) with $8.5 million in combined potential value. The company delivers time-and-materials purchase orders for DNA analysis and forensic testimony in criminal litigation, with individual order ceilings typically ranging from $2,660 to $121,429. Recent representative awards include expert witness services orders valued at $121,429.30 (August 25, 2025), $109,229.30 (August 26, 2025), and $60,339.30 (December 30, 2025) across multiple U.S. Attorney's Offices. Beyond expert witness work, Signature Science holds significant research and development vehicles and task-order capacity. The company is a prime contractor on the Department of the Army's Joint PEO Chemical and Biological Defense indefinite-delivery vehicle carrying $8.31 billion in combined potential value across six awards, driven by the FAR Forward Biological Sequencing (FFBS) Increment 2 Other Transaction IDV ($12.8 million ceiling, awarded June 5, 2026) and other chemical and biological threat-assessment work. The company also holds a Defense Advanced Research Projects Agency Other Transaction IDV with a ceiling of $89.0 million ($30.5 million directly supporting the Process Intensified Energetics research program, awarded December 18, 2024), a $3 million Basic Ordering Agreement with the National Institute of Standards and Technology for AI assessment and benchmarking of chemical and biological model capabilities (awarded August 18, 2025), and positions on the GSA Multiple Award Schedule and DHS Science and Technology Directorate's Environmental Services indefinite-delivery vehicle (61 task orders, $104.3 million combined potential value).
Signature Science's customer concentration sits almost entirely with DOJ—the U.S. Attorney's Offices alone represent 83% of award count and 96% of potential value across the top five customers. The Department of Homeland Security Science and Technology Directorate represents the second-largest customer by potential value at $257.2 million across 45 awards. The company serves 46 distinct federal agencies across the federal footprint. The vendor's capability portfolio is grounded in forensic science and genomic technology, with NAICS and PSC coding that reflects the concentration: 753 awards under All Other Legal Services (NAICS 541110), 159 under Testing Laboratories and Services (NAICS 541380), and 899 awards under the Expert Witness PSC. Core service lines beyond litigation support include chemical and biological threat assessment, critical infrastructure security research, research and development in specialized scientific domains, and artificial intelligence safety evaluation and benchmarking.
Activity has grown significantly—19 awards in 2022 to 205 in 2025—with a sharp acceleration starting in 2023. Signature Science generated SCI-reportable invoiced federal revenue of $33.1 million across fiscal years 2022 through 2025, declining slightly from $9 million (FY2022) to $7.8 million (FY2025) as measured through SCI-covered service contracts above the $150,000 threshold. The dataset shows a stable federal services workforce of roughly 24–28 personnel across this period (24.5 FTEs reported in FY2025 across SCI-reportable prime contracts). Government-paid hourly rates on federal services work ran a median of $133.08 per hour, with rates at the 10th percentile around $30.76/hr and at the 90th percentile around $206.12/hr, reflecting a mix of clerical, technical, and senior specialist labor. The company's GSA Schedule labor portfolio spans seven categories at hourly rates from $52.20 for clerical roles to $270.67 for principal-level engineers and scientists, with no security-clearance roles offered. Across SCI-reportable prime contracts, the company performs its own work with minimal subcontractor reliance (0% average sub-hours share), positioning itself as a prime-focused delivery organization.
Within the next 24 months, 163 awards carrying $53.3 million in combined potential value reach ultimate completion, exposing Signature Science to recompete pressure concentrated in the U.S. Attorney's Offices expert witness purchase-order stream. Signature Science operates from headquarters in Austin, Texas, with a San Antonio location supporting Southwest Research Institute's broader operations. The company is registered with SAM.gov and competes across full-and-open federal solicitations without participation in set-aside programs. As of August 2026, the vendor holds prime status on multiple significant indefinite-delivery vehicles anchoring its position across DOJ litigation support, DHS research and development, and Army chemical and biological defense missions.
Quick answers
Is Signature Science LLC registered in SAM.gov?
Yes. Signature Science LLC's SAM.gov registration is active through May 14, 2027.
Which contract vehicles does Signature Science LLC hold?
Signature Science LLC holds a place on 6 federal contract vehicles, including FSS-899, JE-RDAP and MAS.
How much has Signature Science LLC received in federal contracts?
Federal contracts obligated $14,656,086 to Signature Science LLC in fiscal year 2025 and $52,007,951 in fiscal years 2023 through 2027.
How does Signature Science LLC rank among federal contractors?
Signature Science LLC ranked #5 in PSC B504, #16 in PSC R424 and #21 in NAICS 541199 in FY2025.
What is Signature Science LLC's most recent federal award?
Signature Science LLC's most recent federal contract award is Expert witness services (15JA1626P00000635), from US Attorney's Offices (OBD), on August 6, 2026.
On GovTribe
See Signature Science LLC's full federal record
- Federal contract awards
- IDV awards
- Contract vehicles
- Federal grant awards
- Subcontracting relationships
- Funding analysis by agency, NAICS and set-aside
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