Sage Science, Inc.

Sage Science, Inc., doing business as Sage Science, manufactures DNA and nucleic acid size-selection electrophoresis instruments and associated consumables for federal research agencies, operating exclusively as a prime contractor on small-dollar purchase orders and research grants. The company is a for-profit biotechnology manufacturer headquartered in Beverly, Massachusetts, classified under NAICS 334516 (Analytical Laboratory Instrument Manufacturing), and competes under both small business set-asides and full-and-open solicitations with roughly equal frequency across its federal portfolio.

Sage Science's capability footprint centers on automated DNA size selection systems — primarily the BluePippin and SageELF brands, which use pulsed-field electrophoresis to precisely size nucleic acid samples for next-generation sequencing library preparation and genomic research workflows. The company's federal work includes equipment sales ranging from $13,755 to $100,500 per purchase order and extended warranty services. Representative awards include a $17,085 small-business-set-aside delivery to the National Institute of Standards and Technology's Molecular Mycology Lab (April 2026), a $25,870 BluePippin system to the National Institute on Aging (December 2023), and a $100,500 multi-unit electrophoresis system sale to USDA's Animal and Plant Health Inspection Service Veterinary Services (April 2022). Sage Science has also received two federal research grants from the National Human Genome Research Institute (NHGRI) under its project-grant program for development of a high-throughput, cost-effective gel-based size-selection system compatible with standard liquid-handling robotics for long-read sequencing library preparation, with awards dated August 2022 and completion dates extending through June 2026.

Customer concentration is moderate and distributed across civilian research and agricultural agencies. The top five customer organizations by award count represent 37 percent of recent awards: the National Human Genome Research Institute leads with 13 awards valued at $145 thousand; USDA's Agricultural Research Service (across multiple regional divisions) accounts for 19 awards combined; the FDA has placed 6 awards; and the National Institute on Aging holds 4 awards. By potential-value ranking, NHGRI and FDA each anchor roughly $116–145 thousand in cumulative ceiling, followed by USDA APHIS Veterinary Services at $111 thousand. Sage Science operates across 38 distinct federal agencies in its recent portfolio, reflecting broad but shallow penetration of federal research and agricultural markets.

Activity has declined from a 2022 peak of seven awards down to one award in 2025 and one in early 2026, though the source data spans fifteen years and includes 103 total awards with a combined potential value of $1.5 million. The combined dollars obligated across all awards total $7.4 million, reflecting invoiced revenue that substantially exceeds standing ceiling values — a pattern typical of mature consumables and warranty businesses where repeat orders and multi-year service contracts drive actual spend. Sage Science operates as a 100 percent prime contractor with no recorded subcontract activity, positioning the company as a direct supplier rather than a sub-tier participant in larger federal programs.