High-throughput size-selection system for long-read sequencing library preparation
Ended Project Grant Awarded Last action
- Award ID
- R43HG012531
- Recipient
-
Sage Science, Inc. UEI EA5AFFNALLJ7
- Awarding agency
-
National Human Genome Research Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $641,724
Award facts
- Assistance listing
- 93.172 Human Genome Research
- Completion date
- Place of performance
- Massachusetts, USA
Award details come from USAspending.gov.
Description
- Abstract
- Most long-read DNA sequencing methods depend on library size selection techniques to control and/or improve read lengths. In oxford nanopore and pacbio sequencing protocols, sample loading is dependent on diffusion of library molecules to the reader surface (waveguide surface for pacbio, or membrane for oxford). Since small molecules have a higher rate of diffusion than larger molecules, size selection to eliminate small library fragments can greatly improve library read lengths. Popular methods for elimination of small library elements (generally
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $320,862 | |
| Original award | $320,862 |
Quick answers
Who received award R43HG012531?
R43HG012531 was awarded to Sage Science, Inc. by National Human Genome Research Institute (National Institutes of Health) on August 3, 2022.
How much is award R43HG012531 worth?
$641,724 has been obligated on R43HG012531.
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