Pearl Bio, Inc.
Cambridge, MA
- UEI
- QRR3ELYYB486
- CAGE
- 9B0A4
- SAM.gov registration
- Active through
Company facts
- Self-certified in SAM.gov
- Entity structure
- Corporate Entity (Not Tax Exempt)
- NAICS codes registered in SAM.gov
- SAM.gov registration date
- Physical address
- 700 Main St, Cambridge, MA 02139, USA
- Website
- pearlbio.com
- Employees
- 1-10
- Estimated annual revenue
- $0-$1M
- Industry
-
- Health Care
- Pharmaceuticals, Biotechnology & Life Sciences
- Pharmaceuticals
- SIC code
- 28 Chemical & Allied Products
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Recent federal awards
| Award | Agency | Obligated | Awarded |
|---|---|---|---|
| Small business technology transfer research (sttr) services phase i effort titled scalable production of… | ACC Aberdeen Proving Ground | $249,967 | |
| Development of programmable nanobodies for multi-functionalized biologics - project summary antibody drug conjugates… | National Institute of General Medical Sciences | $295,259 | |
| Small business technology transfer research program | ACC Aberdeen Proving Ground | $1,699,978 | |
| Development of next-generation biologics programmed with multifunctional synthetic chemistries - project summary protein… | National Institute of General Medical Sciences | $549,384 | |
| Sbir phase i: consolidated platform to engineer and produce novel biopolymers for improved biologics -the broader… | National Science Foundation | $274,462 |
About Pearl Bio, Inc.
Pearl Bio, Inc. is a biotechnology company specializing in the development of next-generation biomaterials and protein biologics. Registered to receive federal awards since May 2022, Pearl Bio has secured both federal contracts and grants to support its innovative research and development efforts. The company leverages synthetic biology, genomically recoded organisms, and orthogonal translation systems to create novel biological materials with diverse, non-native components for improved therapeutic efficacy and biomedical applications.
Pearl Bio has been awarded federal contracts from the Office of the Secretary of Defense to advance its research in sequence-defined biopolymers containing non-canonical amino acids. In May 2024, the company received a $1,699,977.77 firm-fixed-price Definitive Contract (W911NF24C0043) for an STTR Phase II project, building upon a previous $249,998.00 STTR Phase I contract (W911NF23P0017) awarded in March 2023. Both contracts were designated as total small business set-asides and focused on the scalable production of sequence-defined biopolymers using recoded cell and cell-free systems. These projects aim to enhance biotechnology and biomanufacturing capabilities, potentially leading to advancements in various defense-related applications.
The company has also secured several federal grants to support its research initiatives. The National Institute of General Medical Sciences (NIGMS) awarded Pearl Bio two Project Grants under the Biomedical Research and Research Training program. One grant (R43GM154591) for $295,259 focuses on developing programmable nanobodies for multi-functionalized biologics, while another (R43GM150368) for $274,692 supports the creation of next-generation protein biologics with multifunctional synthetic chemistries. Additionally, the National Science Foundation awarded Pearl Bio a $274,462 Project Grant (2233560) under the NSF Technology, Innovation, and Partnerships program to develop a next-generation biomanufacturing platform for engineering novel biopolymers. These grants collectively aim to advance Pearl Bio's synthetic biology platform, enabling the production of innovative biological materials with enhanced therapeutic properties and diverse biomedical applications.
Quick answers
What is Pearl Bio, Inc.'s UEI?
Pearl Bio, Inc.'s Unique Entity ID (UEI) in SAM.gov is QRR3ELYYB486.
What is Pearl Bio, Inc.'s CAGE code?
Pearl Bio, Inc.'s CAGE code is 9B0A4.
What is Pearl Bio, Inc.'s primary NAICS code?
Pearl Bio, Inc.'s primary NAICS code is 541714 (Research and Development in Biotechnology (except Nanobiotechnology)).
Where is Pearl Bio, Inc. located?
Pearl Bio, Inc.'s physical address in SAM.gov is 700 Main St, Cambridge, MA 02139, USA.
Is Pearl Bio, Inc. registered in SAM.gov?
Yes. Pearl Bio, Inc.'s SAM.gov registration is active through December 18, 2026.
What is Pearl Bio, Inc.'s most recent federal award?
Pearl Bio, Inc.'s most recent federal contract award is Small business technology transfer research (sttr) services phase i effort titled scalable production of… (W911NF26PA006), from ACC Aberdeen Proving Ground, on April 1, 2026.
On GovTribe
See Pearl Bio, Inc.'s full federal record
- Federal contract awards
- Federal grant awards
- Funding analysis by agency, NAICS and set-aside
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