Project Grant 2233560
Award Date 8/1/23
Completion Date 1/31/24
Dollars Obligated $274K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Cambridge, MA 02142, USA
Similar Awards
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Om Therapeutics Inc. will support the development of a system to enable the rapid, scalable, and cost-effective discovery of new medicines using machine learning. The project aims to encapsulate proteins and small molecules in millions of miniaturized compartments to screen for interactions that could identify novel drug candidates. The key innovations include...
- This National Science Foundation (NSF) Cooperative Agreement award, funded under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, will support the development and commercialization of a cost-effective peptide production platform by the small business Oakgrove Bio LLC. The $1,000,000 project aims to scale-up a recombinant technology that will dramatically decrease the cost of manufacturing peptides, which have significant potential applications ranging from antimicrobials...
- This $1,000,000 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports research by the University of California, San Francisco (UCSF) to design, build, and test synthetic signaling systems built from computationally-designed de novo protein components. The goal is to develop stable, tunable, and modular signaling systems capable of precisely controlling biological processes, with applications in biotechnology such as engineered cells for...
- This Project Grant award from the National Science Foundation (NSF) under its Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Tectaria Bio LLC to engineer cell lines with activated proteasomes for increased biomanufacturing efficiency. The project aims to test the feasibility and application of a novel technology to significantly increase the protein production capabilities of cell lines used in the manufacture of biologics, gene therapies, and vaccines....
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) award provides $274,727 to Weka Biosciences LLC, a woman-owned small business, to develop a novel microbial process for creating a synthetic sugar polymer for use in chiral chromatography. The goal is to produce a more reliable and efficient polymer material to enhance the precision of drug manufacturing and contribute to safer, more effective medications. The 12-month project will focus on...
- This $448,150 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop a DNA-based toolbox for the rapid and precise modulation of cell membrane protein-protein interactions (PPIs). The goal is to establish a modular approach using antibodies and aptamers to enable targeted DNA barcoding of cell membrane proteins, particularly receptor tyrosine kinases. This will allow for the controlled stabilization of specific PPI pairs on living...
- The National Science Foundation (NSF) awarded a $274,966 Project Grant to Remedium Bio Inc., a for-profit organization, under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The grant supports the development of an adjustable gene therapy platform technology that will enable the use of genetic therapeutics beyond rare diseases, tackling large unmet clinical needs such as diabetes, osteoarthritis, and autoimmune diseases. The project aims to develop a dose-adjustable...
- The National Science Foundation (NSF) awarded a $275,000 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Foragr Medicines, Inc. for a SBIR Phase I project titled "High-Throughput Platform for Small Molecule, In-Cell Targeting of Undruggable Proteins via their mRNAs". The project aims to develop a high-throughput drug discovery platform to identify small molecule drugs that can target the mRNA of hard-to-treat diseases, including...
- The National Science Foundation (NSF) awarded a $273,706 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Matmerize, Inc., a for-profit organization, to develop a physics-informed/encoded polymer informatics platform to accelerate the development of advanced polymers and formulations. The project aims to transform the way polymeric materials are developed by adopting advanced artificial intelligence techniques to dramatically expedite the...
- This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant of $545,000 awarded May 15, 2025, supports research to enhance recombinant protein production in Komagataella pastoris (Pichia pastoris), a food-safe yeast widely utilized in biomanufacturing and biological research. The research will deliver scientific outcomes demonstrating how codon usage patterns can be exploited to maximize recombinant protein expression while simultaneously preserving host cellular...