Hyperion Biotechnology, Inc.

Hyperion Biotechnology, Inc., doing business as Hyperion Bio-Technology Inc., is a service-disabled veteran-owned small business (SDVOSB) and certified women-owned small business that delivers environmental testing, laboratory analysis, and water quality monitoring services to the federal government as a prime contractor (99% of recent awards). Headquartered in San Antonio, Texas, the company is self-certified as a small disadvantaged business and operates across NAICS codes 541380 (Testing Laboratories and Services), 541620 (Environmental Consulting Services), and related professional-services codes.

Hyperion's federal portfolio concentrates in Legionella water testing and environmental remediation services for the Department of Veterans Affairs across multiple Veterans Integrated Service Networks. The firm has established itself as a primary provider of water quality monitoring, heterotrophic plate count analysis, dental water system testing, and related infection prevention services to VA medical facilities nationwide. Concrete examples include a $2,000,000 five-year single-award indefinite-delivery contract with VISN 23 for Legionella testing at VHA Black Hills Health Care System (awarded August 2024, running through July 2029), a $1,329,254 single-award IDC with VISN 22 for comprehensive Legionella water testing across Southwest VA medical centers (awarded September 2024, through February 2026), and a $512,028 purchase order from VISN 21 for Legionella water sampling services in San Francisco (awarded November 2025, through November 2030). Beyond water testing, Hyperion recently won a $5,834,699.98 firm fixed-price purchase order from the Department of the Navy Bureau of Medicine and Surgery for applied research ethics support services and human research protection program compliance (awarded February 2025, through August 2030), and a $7,387,978.59 delivery order from Fort Johnson's Directorate of Human Resources for personnel, postal, and administrative support services under a Total Small Business set-aside (awarded August 2024, through August 2027).

Customer concentration is heavily anchored to the VA. The top five customer agencies by award count account for 58% of recent awards: Veterans Integrated Service Network 22 leads with 95 awards worth $10.7 million combined potential value; NIST trails with 65 awards worth $6.5 million; VISN 23 holds 25 awards worth $5.1 million; the Uniformed Services University of the Health Sciences has 25 awards worth $7.1 million; and the Navy Bureau of Medicine and Surgery carries 21 awards worth $29.2 million. By dollars, the Navy Bureau of Medicine and Surgery ranks first ($29.2 million across 21 awards), followed by the Air Force ($12.5 million across 13 awards), Air Education and Training Command ($11.1 million across 5 awards), VISN 22 ($10.7 million across 95 awards), and Army Medical Command ($8.5 million across 6 awards). The tension between these rankings reflects Hyperion's VA footprint of many smaller task orders under standing IDCs and the Navy's smaller count of much higher-value contracts.

Hyperion positions on multiple indefinite-delivery frameworks spanning VA networks and federal supply schedules. The vendor holds a $600,000 blanket purchase agreement with VISN 5 under the GSA Multiple Award Schedule (62 task orders issued for Legionella testing in Baltimore, Maryland, through December 2026), a $1,329,254 single-award IDC with VISN 22 (multiple delivery orders across Southwest facilities through February 2026), a $2,000,000 single-award IDC with VISN 23 for VHA Black Hills testing (through July 2029), a $899,999.99 single-award IDC with VISN 22 (seven delivery orders issued through December 2026), a $340,832.60 single-award IDC with VISN 4 for Legionella testing in Pennsylvania and Delaware (through June 2028), and a $282,750 IDC with VISN 23 for Legionella and heterotrophic plate count testing in Nebraska (through August 2030). The vendor also holds the HR Solutions Personnel Life Cycle Support Services (HRS PLS) IDIQ as a task-order vehicle.

Activity has grown modestly year over year, averaging 27 awards annually over the past five years (25 in 2022, 20 in 2023, 30 in 2024, 35 in 2025, 26 in 2026). Twenty-eight awards totaling $12.1 million in combined potential value face ultimate completion within the next twenty-four months, representing recompete exposure. The vendor operates almost entirely as a prime contractor, with only 4 sub-awards (1% of portfolio) across the recent award footprint. Named sub relationships include work as an Education and Training Compliance Specialist (1 FTE) under Magellan Federal, Inc. on HRPP support services, and coordination with Serco Inc. on personnel life-cycle support services.

On federal service contracts captured in the Service Contract Inventory (SCI), Hyperion reported invoiced revenue of $724 thousand across FY2023–FY2025, with $127 thousand in FY2023 (0.3 FTEs), $288 thousand in FY2024 (0.5 FTEs), and $309 thousand in FY2025 (0.5 FTEs). Government-paid hourly rates on SCI-reportable primes run a median of $211.97 per hour, with rates ranging from approximately $163 at the tenth percentile to $380 at the ninety-fifth percentile. The SCI dataset shows minimal subcontractor engagement across these reportable primes; Hyperion self-performs the vast majority of labor.

The vendor self-performs water testing and environmental analysis work across multiple VA regional networks and standalone federal customer relationships with minimal subcontractor reliance. SDVOSB and women-owned small business set-asides recur across the prime footprint, though a material portion of recent delivery orders and purchase orders carry no set-aside designation, reflecting full-and-open competition or customer-directed non-set-aside ordering decisions. Hyperion's SBA designations expire January 3, 2027, per the most recent certification records in the award summaries.

WOSB, SDVOSB - Biomedical, Biological, CLIA, Laboratory, Fatigue Biomarker, Drug Testing, Saliva, Trials, Exercise, Medical, Health, Science, Administrative, Program, Management, Facilities, Research, Behavioral, Legionella, CDC Elite