Hyperion Biotechnology, Inc.

Hyperion Biotechnology, Inc., doing business as Hyperion Bio-Technology Inc., a San Antonio, Texas-based service-disabled veteran-owned small business and certified women-owned small business, operates as a prime contractor delivering Legionella water testing, environmental analysis, and specialized laboratory services to the Department of Veterans Affairs and the Department of Defense. The vendor competes predominantly under SDVOSB and small-business set-asides, with 99% of its 388 total awards delivered as prime contractor work.

Hyperion's federal portfolio is anchored in environmental testing and water quality monitoring, specifically Legionella detection and remediation across VA medical facilities nationwide. Representative work includes a $2,000,000 single-award indefinite-delivery contract with VHA Black Hills Health Care System (VISN 23) through July 2029 for Legionella water testing at Fort Meade, South Dakota; a $1,329,254 single-award IDC with VISN 22 through February 2026 for comprehensive Legionella testing at Southwest VA medical centers; a $5,834,700 delivery order from the Department of the Navy Bureau of Medicine and Surgery (February 2025 through August 2030) for Human Research Protection Program support services under the 100% SDVOSB set-aside; and a $6,685,546 recompete task order with Fort Johnson's Directorate of Human Resources (August 2024 through August 2026) for personnel, postal, and administrative support under the HR Solutions Personnel Life Cycle Support Services IDIQ. The vendor also holds a $44,220 Total Small Business set-aside with the Army Research Development and Engineering Command for cortisol and amylase analysis supporting stress-mitigation research (August 2024 through September 2027).

Customer concentration is dispersed across the VA system. The Department of Veterans Affairs Veterans Health Administration Veterans Integrated Service Network 22 leads by volume (86 awards, $8.7 million combined potential value), followed by NIST (65 awards, $6.5 million), the Uniformed Services University of the Health Sciences (25 awards, $7.1 million), and VISN 23 (24 awards, $5.1 million). By potential value, the Department of the Navy Bureau of Medicine and Surgery anchors at $29.2 million (21 awards), followed by the Department of the Air Force ($12.5 million) and Air Education and Training Command ($11.1 million). The concentrated VA footprint reflects Hyperion's specialist positioning in water testing; the Navy contract and Air Force work signal recent portfolio diversification into broader defense and health-systems consulting.

Hyperion holds positions on five parent vehicles: a Blanket Purchase Agreement (DOCSB134111BR0002, 62 task orders, $6.2 million), an IDC (36C25818D0056, 54 task orders, $4.1 million), an IDC (36C26224D0183, 24 task orders, $1.3 million), an IDC with Uniformed Services University (HU000114D0003, 24 task orders, $3.1 million), and an Air Force IDC (FA890006D6018, 22 task orders, $7.8 million). The vendor also operates multiple VA-specific single-award IDCs and BPAs across individual VISNs, including agreements with VISN 5 ($600,000 BPA), VISN 4 ($340,833 IDC), VISN 15 ($150,000 IDC), and VISN 23 ($282,750 IDC).

Activity has remained steady at 20–35 awards per year over the past five years, with 15 awards in 2026 (partial-year count as of mid-July). Thirty-one awards totaling $10.8 million combined potential value face ultimate completion within the next twenty-four months, representing moderate recompete exposure concentrated in VA regional networks and the Navy HRPP contract.

SCI-reported invoicing totaled $416 thousand across FY2023–FY2024 ($127 thousand in FY2023 across 0.3 FTEs; $288 thousand in FY2024 across 0.5 FTEs), reflecting a small subset of the vendor's federal services activity captured above the $150,000 reporting threshold. Government-paid hourly rates on SCI-reportable contracts ranged from $163/hour (10th percentile) to $380/hour (90th percentile), with a median around $212/hour. The vendor self-performs across SCI records with zero subcontractor engagement reported. The broader award portfolio indicates Hyperion operates primarily through 100% SDVOSB and small-business set-asides and does not pursue full-and-open competition; recent sub-awards show Hyperion supporting Serco Inc. and Magellan Federal Inc. on education, training compliance, and health-systems consulting tasks, demonstrating capacity to sub on larger integrator-led programs beyond its core VA footprint.

WOSB, SDVOSB - Biomedical, Biological, CLIA, Laboratory, Fatigue Biomarker, Drug Testing, Saliva, Trials, Exercise, Medical, Health, Science, Administrative, Program, Management, Facilities, Research, Behavioral, Legionella, CDC Elite