American Type Culture Collection

American Type Culture Collection (ATCC), a nonprofit biological resource center based in Manassas, Virginia, operates as a prime federal contractor providing collection, authentication, production, preservation, and distribution of microorganisms, cell lines, reagents, and biological reference materials to civilian health and research agencies. ATCC competes in full-and-open procurement with no set-aside designations; the vendor serves fifty distinct federal customer agencies across over 1,100 recent awards with combined potential value of $12.22 billion.

ATCC's customer base concentrates heavily in the National Institutes of Health ecosystem. The National Institute of Allergy and Infectious Diseases (NIAID) alone anchors the portfolio with 35 awards valued at $1.83 billion combined potential value (15% of total portfolio), followed by the Centers for Disease Control and Prevention Pittsburgh (30 awards, $957.3 million), the National Cancer Institute (32 awards, $443.3 million), and the Office of the Assistant Secretary for Preparedness and Response (10 awards, $346 million). These four customers account for 31% of combined portfolio potential value. ATCC's largest definitive contract is the $333.7 million Biological and Emerging Infections Research Resources Program (BEI-RRP) with NIAID, awarded October 2023 with performance through October 2030, under which ATCC operates a central repository serving approximately 12,000 registered users and maintaining around 17,000 unique items. Four major subcontractors support BEI-RRP operations: the University of Texas Medical Branch at Galveston, Colorado State University's Veterinary Diagnostic Laboratory, the CDC Foundation, and Xpand Corporation.

ATCC's recent capability work demonstrates the breadth of its biological services portfolio. Representative prime contracts include a $333.7 million definitive contract with NIAID for repository and biological materials operations through 2030; a $545.5 million single-award indefinite delivery contract with NIAID for quality-assured central repository services including acquisition, authentication, storage, inventory, and distribution; a $320 million single-award indefinite delivery contract with the National Cancer Institute for field and biospecimen support services through June 2027 with options through 2032; a $146.3 million single-award indefinite delivery contract with NIAID for preclinical infectious disease models including small animal models, non-human primate models, and alternative animal replacement models through July 2031; a $15.5 million delivery order from NIAID under the In Vitro Assessments of Antimicrobial Activity (IVAAA) IDIQ for production of well-characterized challenge material of Biosafety Level 3 and 4 viruses through April 2026; an $88.9 million delivery order from the Office of the Assistant Secretary for Preparedness and Response for biological sample storage and distribution supporting medical countermeasure evaluation through September 2028; a $5.4 million delivery order from the National Cancer Institute for biospecimen and assay support services under the Division of Cancer Epidemiology and Genetics Field and Biospecimen Support Services IDIQ through September 2029; and a $338,178.57 purchase order from the National Institute of Standards and Technology for monoclonal antibody reference material vialing services through April 2027.

ATCC holds position on a multi-billion-dollar OASIS+ Unrestricted government-wide contract awarded by GSA in December 2024 with performance through December 2029, where the Defense Health Agency has already issued a delivery order. The vendor also sits on major civilian agency IDIQs including a $136.6 million NIAID evaluation and testing services contract for vaccines and other biologics awarded September 2025 through September 2035, a $148 million CDC Diagnostic Testing IDIQ awarded September 2025 through September 2030, and a $30 million NIAID preclinical services contract for biopharmaceutical product development through September 2030. Additional vehicles include an $2 million CDC DNA Plating & Storage IDIQ through August 2026 and a $4.055 million National Cancer Institute single-award contract for retrovirus assay and viral stock preparation through September 2029.

Activity has been steady, averaging 9 awards per year across the past five years with recent annual volume at 10 awards in 2025. Eleven awards face ultimate completion within the next twenty-four months with combined potential value of $10.5 million, representing modest recompete exposure. ATCC's federal grant footprint includes recipient and sub-recipient awards from the National Institute of Allergy and Infectious Diseases, the Defense Threat Reduction Agency, the Office of the Director (NIH), and the Department of Agriculture's Central Program Planning Coordination and Support office. Grant work includes a $263,771 Defense Threat Reduction Agency project grant for genome-wide mapping of host proteome interactions for broad-spectrum alphavirus countermeasures (completed October 2023); a cooperative agreement with the Department of Agriculture for the establishment of a remote biological materials repository in partnership with the National Bio- and Agro-Defense Facility (through July 2026); and NIAID-funded facility renovation grants including support for a biomaterial manufacturing suite expansion within a high-containment facility currently under design (through November 2026) and high-containment facility renovations supporting the Biodefense and Emerging Infections Resources program (through May 2026). ATCC has provided over 1.36 million reagents to over 14,000 investigators at 3,740 institutions across 119 countries supporting infectious disease research and pandemic preparedness.

ATCC operates as a prime contractor on 99% of recent awards, with only 15 sub-award relationships (1% of portfolio). Across SCI-reportable prime federal service contracts — a strict subset capturing contracts above the $150,000 threshold — ATCC invoiced $138.9 million in FY2022–FY2024, with SCI-reported FTE delivery at 72.9 FTEs in FY2022, 102 FTEs in FY2023, and 140 FTEs in FY2024. Government-paid hourly rates on federal services contracts run a median of $205.99 per hour, with senior labor pricing reaching the 90th percentile of $380.82 per hour. Across SCI-reportable prime contracts, subcontractors perform approximately 10% of total contractor hours, with 19 named subcontractors reported. Sub-award engagement includes named subs under prime contracts such as Government Scientific Source Inc., Agilent Technologies Inc., IT1 Source LLC, Panamerica Computers Inc., Arete Associates, and Illumina Inc. for facility management and sample aliquoting work supporting the National Cancer Institute. ATCC's sub-recipient grant work flows through university prime grantees including Yale University, the University of Cincinnati, Albert Einstein College of Medicine, Harvard College, and Iowa State University for infectious disease immunology and microbiome research supporting NIAID-funded initiatives.