Birth Defects and Developmental Disabilities - Prevention and Surveillance

Active

Assistance listing
93.073
Agency
Grant awards
159 $278,584,490 in federal obligations

Program facts

Assistance type
  • Cooperative Agreement
Treasury account
  • 75-0958-1-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The CDC's Centers for Disease Control and Prevention (NCBDDD) awards grants under CFDA 93.073 for birth defects prevention and surveillance, with the most recent award disbursed August 1, 2021, and multiple opportunities currently open for 2026 applications.

The program funds population-based surveillance systems tracking birth defects and developmental disabilities across the lifespan, prevention research on specific conditions including congenital heart defects, neural tube defects, and fetal alcohol spectrum disorders, health promotion and evidence-based educational programs targeting patients and healthcare providers, and capacity-building activities such as epidemiological training fellowships and data modernization initiatives. Recent awards span surveillance of congenital heart defects in multiple states, implementation of alcohol screening and brief intervention in clinical settings to prevent prenatal alcohol exposure, dissemination of evidence-based information on ADHD and Tourette syndrome, and longitudinal birth defects research examining medication and infectious disease exposures during pregnancy.

All awards are Cooperative Agreements, representing 100 percent of the 159 grants awarded since 2010. The CDC's National Center on Birth Defects and Developmental Disabilities is the sole funding source. Combined federal dollars obligated total $278.6 million, with non-federal cost-share adding $6.8 million, reflecting discretionary matching in some projects. Award magnitudes vary significantly—recent examples include a $58.6 million five-year award for health promotion programs serving people with mobility disabilities, a $9.3 million award on Tourette syndrome education, and multiple state-level surveillance projects ranging from $3.7 million to $8.4 million over similar periods. Award frequency has declined markedly: 60 awards in 2016, but only one in 2021, suggesting reduced activity or a shift in funding strategy.

Three opportunities posted in 2026 signal program reactivation. CDC-RFA-DD-27-0065 (posted August 17, 2026) solicits cooperative agreements for birth defects and stillbirth surveillance with data modernization via electronic case reporting; CDC-RFA-DD-27-0028 (posted July 24, 2026) funds maternal-child health surveillance addressing fetal alcohol spectrum disorders, neonatal abstinence syndrome, and cytomegalovirus, with Component A requiring public health authority and legal access to clinical data. A December 2025 opportunity (CDC-RFA-DD-26-0222, due October 26, 2026) seeks cooperative agreements for long-term health outcomes surveillance in spina bifida, with two components supporting longitudinal data collection and protocol development for urologic management in infants and young children.

Eligible applicants include state and local health departments, universities, tribal governments, nonprofits, and some for-profit organizations. Project periods run 1 to 5 years, with awards typically supporting the first 12-month budget period explicitly and indicating recommended support for the remainder. Cooperative agreements carry requirements for satisfactory progress documentation and non-competitive continuation eligibility where funds allow.

Objective and description

Objective

To work with State health agencies, universities, and public and private nonprofit organizations in planning, implementing coordinating or evaluating programs, research or surveillance activities related to improved birth outcomes, prevention of birt

Description

To work with State health agencies, universities, and public and private nonprofit organizations in planning, implementing coordinating or evaluating programs, research or surveillance activities related to improved birth outcomes, prevention of birth defects, and the improvement of infant and child health and developmental outcomes. To provide a national, State or local focus for the prevention of conditions of persons with birth defects; to employ epidemiological methods to set priorities, build capacity and direct health promotion interventions for persons with birth defects; to expand public health training opportunities through fellowships to introduce geneticists, epidemiologists, and clinicians to public health practice through education, training and career-enhancing experiences. To enhance surveillance and research for birth defects; to prevent congenital heart defects and other major birth defects associated with medication use during pregnancy; to advance neural tube defect prevention; and enhance the quality and usefulness of newborn screening data and programs.

Eligibility

Applicant eligibility

Full and open competition

Beneficiary eligibility

State; Consumer; Local; Public nonprofit institution/organization; Federally Recognized Indian Tribal Governments; Individual/Family; Private nonprofit institution/organizations and others.

Uses of assistance

Funds may be used to strengthen, to expand, to build upon or to enhance research, surveillance, health promotion, education, prevention/intervention activities that contribute to the mission and activities of the Division of Birth Defects and Infant Disorders. Funds may be used to improve and strengthen State and local public health infrastructure by providing technical assistance to other appropriate health agencies, organizations, special groups or coalitions. Funds may be used to support capacity building, program planning, development, implementation, evaluation, and surveillance for birth defects, infant and child health and developmental outcomes, including related health promotion, education and training, prevention/intervention. Funds may also be used to coordinate the dissemination of prevention information to the general public, target populations and among state and local agencies and public and private sector organizations in the United States. Funds may not be used for direct curative or rehabilitative services.

Use restrictions

Funds may not be used for direct curative or rehabilitative services.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

In general, applications are reviewed on the basis of scientific/technical merit, with attention given to such matters as: (1) The degree to which the applicant satisfies the essential requirements and possesses other desired characteristics, such as depth, breadth, and merit of the overall application relative to the types of projects proposed; (2) clarity of purpose and overall qualifications, adequacy and appropriateness of personnel to accomplish proposed prevention research projects and demonstration projects, and the nation's health priorities and needs; (3) ability to generalize, translate and disseminate to State or local health departments, and other appropriate national regional, and local public health agencies and organizations; (4) reasonableness of the proposed budget in relation to the work proposed.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Renewals

Cooperative agreement period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government. If additional support is desired to continue a project beyond the approved project period, an application for competing continuation must be submitted for review in the same manner as a new application. Projects are renewable for periods of 1 to 4 years.

Grant opportunities

Opportunity Status Posted Applications due
Surveillance and Case Control Study of Stillbirth and Birth Defects (SUCCSSBD) CDC-RFA-DD-27-0065 Forecasted —
Maternal-Child Surveillance and Partnerships for Action, Results, and Knowledge CDC-RFA-DD-27-0028 Forecasted —
Long-term health outcomes of people living with spina bifida CDC-RFA-DD-26-0222 Open
Understanding and Promoting Resources and Opportunities for People with Autism and Fragile X and their Families Across the Lifespan CDC-RFA-DD-26-0025 Closed
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) PA-27-100 Open
Surveillance of Congenital Heart Defects Among Children, Adolescents, and Adults CDC-RFA-DD-24-0051 Closed
Surveillance of Muscular Dystrophies CDC-RFA-DD-24-0064 Closed
Surveillance of Spina Bifida across the Lifespan CDC-RFA-DD-24-0065 Closed
Implementing Evidence-Based Health Promotion Programs for Attention-Deficit Hyperactivity Disorder (ADHD) or Tourette Syndrome (TS) CDC-RFA-DD-24-0055 Closed
Documenting outcomes associated with Persistent Tic Disorders (including Tourette Syndrome) in Children, Adolescents, and Young Adults through Surveillance CDC-RFA-DD-24-0083 Closed
Enhancing partnerships to address birth defects, infant disorders and related conditions, and the health of pregnant and postpartum people CDC-RFA-DD-23-0004 Closed
Pregnant People-Infant Linked Longitudinal Surveillance CDC-RFA-DD-23-0003 Closed
Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) RFA-DD-23-001 Closed
PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) PA-22-177 Closed
PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-22-176 Closed
Population-based Surveillance of Outcomes, Needs, and Well-being of Children and Adolescents with Congenital Heart Defects CDC-RFA-DD22-2203 Closed
Pilot Spina Bifida Surveillance Project CDC-RFA-DD22-2204 Past —
National Partnerships to Address Prenatal Alcohol and Other Substance Use and Fetal Alcohol Spectrum Disorders CDC-RFA-DD22-2201 Past —
I-FASD: Understanding Clinical Data and Pathways to Inform Surveillance of Children with Fetal Alcohol Spectrum Disorders CDC-RFA-DD22-2202 Past —
PHS 2021-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-21-259 Closed
PHS 2021-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) PA-21-260 Closed
Emergency Awards: Exosome-based Non-traditional Technologies Towards Multi-Parametric and Integrated Approaches for SARS-CoV-2 (U18 Clinical Trial Not Allowed) RFA-OD-20-018 Closed
Characterizing the Natural History of Fragile X Syndrome to Inform the Development of Intervention Outcome Measures RFA-DD-21-002 Closed
PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) PA-20-261 Closed
PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-20-260 Closed
PHS 2020-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) PA-20-262 Closed
Advancing Population-Based Surveillance of Birth Defects CDC-RFA-DD21-2101 Closed
Study to Explore Early Development (SEED) Follow up Studies RFA-DD-21-001 Closed
PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required PA-19-273 Closed
PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed PA-19-272 Closed
Implementing Evidence-Based Health Promotion Programs for Children with Attention-Deficit/Hyperactivity Disorder (ADHD) or Tourette Syndrome (TS) CDC-RFA-DD19-1904 Closed
Reaching Healthcare Professionals in the Prevention of Fetal Alcohol Spectrum Disorders CDC-RFA-DD18-1803 Closed
Promoting Resources for Fetal Alcohol Spectrum Disorders Awareness and Prevention CDC-RFA-DD18-1801 Closed
Implementing Alcohol Screening and Brief Intervention in Healthcare Systems Providing Women's Health Services CDC-RFA-DD18-1802 Closed
PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-18-574 Closed
Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II RFA-DD-18-001 Closed
PHS 2017-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) PA-17-302 Closed
Surveillance, intervention, and referral to services activities for infants with microcephaly or other adverse outcomes linked with the Zika virus CDC-RFA-DD17-1702 Closed
Coordinating Center for Research to Promote the Health of Children with Birth Defects and People with Developmental and Other Disabilities RFA-DD-17-001 Closed
Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE): Study to Explore Early Development (SEED) 3 RFA-DD-16-001 Closed
Enhancing Public Health Surveillance of Autism Spectrum Disorders and Other Developmental Disabilities through the Autism and Developmental Disabilities Monitoring (ADDM) Network CDC-RFA-DD15-150102CONT16 Closed
Stillbirth Risk Factor Pilot Project Centers for Birth Defects Research and Prevention (CBDRPs) RFA-DD-15-004 Closed
Public Health Research on Modifiable Risk Factors for Spina Bifida RFA-DD-15-001 Closed
Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) RFA-DD-13-003 Closed
Surveillance of Birth Defects in Low and Middle Income Countries CDC-RFA-DD11-1104 Closed
Show all 45

Grant awards

Award Recipient Federal obligations Awarded
National center on health, physical activity and disability - the healthcare system and public health community are… NU27DD000022 University Of Alabama At Birmingham $52,641,758
Surveillance of congenital heart defects among children, adolescents, and adults, component a NU50DD000057 Emory University $3,885,954
Surveillance of congenital heart defects among children, adolescents, and adults NU50DD000055 University Of Arizona $3,760,000
Implementing evidence-based health promotion programs for children with attention deficit/hyperactivity disorder NU38DD000002 Chadd, Inc. (Children & Adults With Attention-Deficit / Hyperactivity Disorder) $7,650,000
The tourette association of america offers evidence-based informational programs and develops/disseminates resources on… NU38DD000001 Tourette Association Of America Inc. $9,399,504
Family physicians addressing risky alcohol use to prevent fetal alcohol spectrum disorders NU84DD000010 American Academy Of Family Physicians $1,693,660
Reaching healthcare professionals to prevent fetal alcohol spectrum disorders (fasd) NU84DD000009 University Of Texas At Austin $5,056,995
Prevention of fasds through national nursing organizations NU84DD000006 University Of Alaska Anchorage $1,750,000
Fasd - SBI in women's health NU84DD000005 University Of Alaska Anchorage $2,800,000
Alcohol screening in planned parenthood to increase resiliency (asppire) NU84DD000004 University Of Connecticut Health Center $2,765,497

Latest 10 of 159 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 95 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $752,326
FY2025 -$31
FY2024 $42,074,108
FY2023 $75,422,010
FY2022 $49,197,403
FY2021 $25,279,198
FY2020 $34,119,931
FY2019 $28,901,590
FY2018 $20,588,171
FY2017 $28,001,840
FY2016 $40,129,957
FY2015 $22,324,371
FY2014 $16,894,784
FY2013 $12,836,960
FY2012 $12,173,484
FY2011 $6,951,674
FY2010 $185,000
Show all 17

Quick answers

What is Assistance Listing 93.073?

Assistance Listing 93.073 is Birth Defects and Developmental Disabilities - Prevention and Surveillance, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Birth Defects and Developmental Disabilities - Prevention and Surveillance?

Its CFDA number is 93.073: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.073 awarded?

159 grant awards under 93.073 have obligated $278,584,490 in federal funds to 95 recipients.

Who receives the most funding from 93.073?

The recipients obligated the most under Birth Defects and Developmental Disabilities - Prevention and Surveillance are University Of Alabama At Birmingham ($52,641,760), University Of North Carolina At Chapel Hill ($16,677,089) and Massachusetts Department Of Public Health ($14,227,938).

How much did 93.073 obligate in fiscal year 2025?

Grants under 93.073 obligated -$31 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.073?

4 listed opportunities under 93.073 are open or forecasted. The latest, Surveillance and Case Control Study of Stillbirth and Birth Defects (SUCCSSBD), was posted on August 17, 2026.

On GovTribe

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