Long read sequencing services
Closed Solicitation Posted
This opportunity was awarded. See the award notice from .
- Solicitation number
- 75N95025Q00023
- Agency
- National Institute on Drug Abuse National Institutes of Health, Department of Health and Human Services
- Responses due
- Set-aside
- Total Small Business
Opportunity facts
- NAICS code
- 621511 Medical Laboratories
- PSC
- Q301 Reference Laboratory Testing
- Place of performance
- United States
- Points of contact
-
- Rashiid Cummins rashiid.cummins@nih.gov
Notice details come from SAM.gov. Updated .
About this opportunity
The National Institutes of Health National Institute on Drug Abuse is seeking long read sequencing services for the Global Parkinson's Genetics Program (GP2), which aims to research patient samples associated with Parkinson's Disease. The solicitation, numbered 75N95025Q00023, requires a contractor to perform long read sequencing on 500 human genomic DNA samples using the PacBio Revio platform with specific technical requirements, including generating 25X output per sample. The government will evaluate proposals based on technical capability, past performance, and price, with technical capability and past performance being significantly more important than price. Responses must be submitted electronically to Rashiid Cummins by December 10, 2024, at 12:00 PM Eastern Time, and all offerors must have an active registration in the System for Award Management (SAM). The solicitation incorporates various Federal Acquisition Regulation (FAR) provisions and clauses by reference, with full text available upon request.
The contract is set aside exclusively for small businesses with a size standard of $41.5 million under NAICS code 621511. The anticipated period of performance is twelve months, with the government expecting to award a firm fixed-price purchase order. Contractors must provide DNA fragmentation, library preparation, and bioinformatics support, including variant calling and structural variant detection. The work will be performed at the contractor's site, with no travel required, and a dedicated project manager must be assigned as the government point of contact. Deliverables include raw data, UBAM, and VCF files to be securely transported to CARD/GP2's Google Cloud within six weeks of initial quality control approval. The contractor will also be responsible for securely storing samples for three months after analysis and may provide optional DNA extraction services for the 500 samples. The place of performance is within the United States, with sample pickup via daily courier service to the NIH Bethesda campus.
Notice text
2 versions
Update #2 · Latest ·
Amendment 01 to solicitation 75N95025Q00023 has been posted. This amendment contains the following changes:
- Responses to questions are being attached and hereby incorporated into the solicitation as an attachment "D-Attachment-Questions"
- An updated SOW is being attached and hereby incorporated into the solicitation as an attachment "D-Attachment-SOW Long read sequencing services revised 12.9.2024"
- The deadline to submit quotes has been extended to December 13, 2024 at 12:00 PM Eastern Time
(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
(ii) The solicitation number is 75N95025Q00023 and the solicitation is issued as a request for quotation (RFQ).
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) Number 2025-01, with an effective date November 12, 2024.
(iv) The associated NAICS code is 621511 and the small business size standard is $41.5 million. This requirement is set-aside for small businesses.
(v) This requirement is for the following service: Long read sequencing services. Please see the attached Statement of Work (SOW) for detailed requirements.
(vi) The purpose of this requirement is to procure long read sequencing services for the Global Parkinson’s Genetics Program (GP2) which will research patient samples associated with Parkinson’s Disease.
(vii) The Government anticipates award of a firm fixed-price purchase order for this acquisition and the anticipated period of performance is twelve (12) months.
(viii) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998), applies to this acquisition. This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at these addresses:
https://www.acquisition.gov/browse/index/far
https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html
(End of provision)
The following provisions apply to this acquisition and are incorporated by reference:
- FAR 52.204-7 System for Award Management (NOV 2024)
- FAR 52.204-16 Commercial and Government Entity Code Reporting (AUG 2020)
- FAR 52.212-1 Instructions to Offerors--Commercial Items (SEPT 2023)
- FAR 52.212-3 Offeror Representations and Certifications – Commercial Items (MAY 2024)
- HHSAR 352.239-73 Electronic and Information Technology Accessibility Notice (December 18, 2015)
The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at these addresses:
https://www.acquisition.gov/browse/index/far
https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html
(End of clause)
The following clauses apply to this acquisition and are incorporated by reference:
- FAR 52.204-13 System for Award Management Maintenance (OCT 2018)
- FAR 52.204-18 Commercial and Government Entity Code Maintenance (AUG 2020)
- FAR 52.212-4 Contract Terms and Conditions Commercial Items (NOV 2023). Addendum to this FAR clause applies to this acquisition and is attached.
- HHSAR 352.222-70 Contractor Cooperation in Equal Employment Opportunity Investigations (December 18, 2015)
The following provisions and clauses apply to this acquisition and are incorporated as an attachment. Offerors MUST complete the provisions at 52.204-24 and 52.204-26 and submit completed copies as separate documents with their proposal.
- 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (NOV 2021)
- 52.204-26 Covered Telecommunications Equipment or Services-Representation (OCT 2020)
- FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (NOV 2024)
- NIH Invoice and Payment Provisions
(ix) The provision at FAR clause 52.212-2, Evaluation-Commercial Products and Commercial Services (NOV 2021), applies tothis acquisition.
(a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: (i) technical capability of the service offered to meet the Government requirement; (ii) past performance [see FAR 13.106-2(b)(3)]; and (iii) price.
Technical capability and past performance, when combined, are significantly more important than price.
(b) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award.
(x)The Offerors to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications-Commercial Items (MAY 2024), with its offer. If the offeror has completed FAR clause 52.212-3 at www.sam.gov, then the offeror does not need to provide a completed copy with its offer.
(xi) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition.
(xii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.
(xiii) Responses to this solicitation must include clear and convincing evidence of the offeror’s capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price proposal must include the labor categories, an estimate of the number of hours required for each labor category, fully loaded fixed hourly rate or each labor category, breakdown and rationale for other direct costs or materials, and the total amount.
The Unique Entity ID from SAM.gov, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.
Allquotationsmust be received by December 13, 2024 at 12:00 PM Eastern Time and must reference solicitation number 75N95025Q00023. Responses must be submitted electronically to Rashiid Cummins, Contract Specialist, at rashiid.cummins@nih.gov
Fax responses will not be accepted.
Update #1 ·
(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
(ii) The solicitation number is 75N95025Q00023 and the solicitation is issued as a request for quotation (RFQ).
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) Number 2025-01, with an effective date November 12, 2024.
(iv) The associated NAICS code is 621511 and the small business size standard is $41.5 million. This requirement is set-aside for small businesses.
(v) This requirement is for the following service: Long read sequencing services. Please see the attached Statement of Work (SOW) for detailed requirements.
(vi) The purpose of this requirement is to procure long read sequencing services for the Global Parkinson’s Genetics Program (GP2) which will research patient samples associated with Parkinson’s Disease.
(vii) The Government anticipates award of a firm fixed-price purchase order for this acquisition and the anticipated period of performance is twelve (12) months.
(viii) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998), applies to this acquisition. This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at these addresses:
https://www.acquisition.gov/browse/index/far
https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html
(End of provision)
The following provisions apply to this acquisition and are incorporated by reference:
- FAR 52.204-7 System for Award Management (NOV 2024)
- FAR 52.204-16 Commercial and Government Entity Code Reporting (AUG 2020)
- FAR 52.212-1 Instructions to Offerors--Commercial Items (SEPT 2023)
- FAR 52.212-3 Offeror Representations and Certifications – Commercial Items (MAY 2024)
- HHSAR 352.239-73 Electronic and Information Technology Accessibility Notice (December 18, 2015)
The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at these addresses:
https://www.acquisition.gov/browse/index/far
https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html
(End of clause)
The following clauses apply to this acquisition and are incorporated by reference:
- FAR 52.204-13 System for Award Management Maintenance (OCT 2018)
- FAR 52.204-18 Commercial and Government Entity Code Maintenance (AUG 2020)
- FAR 52.212-4 Contract Terms and Conditions Commercial Items (NOV 2023). Addendum to this FAR clause applies to this acquisition and is attached.
- HHSAR 352.222-70 Contractor Cooperation in Equal Employment Opportunity Investigations (December 18, 2015)
The following provisions and clauses apply to this acquisition and are incorporated as an attachment. Offerors MUST complete the provisions at 52.204-24 and 52.204-26 and submit completed copies as separate documents with their proposal.
- 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (NOV 2021)
- 52.204-26 Covered Telecommunications Equipment or Services-Representation (OCT 2020)
- FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (NOV 2024)
- NIH Invoice and Payment Provisions
(ix) The provision at FAR clause 52.212-2, Evaluation-Commercial Products and Commercial Services (NOV 2021), applies tothis acquisition.
(a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: (i) technical capability of the service offered to meet the Government requirement; (ii) past performance [see FAR 13.106-2(b)(3)]; and (iii) price.
Technical capability and past performance, when combined, are significantly more important than price.
(b) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award.
(x)The Offerors to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications-Commercial Items (MAY 2024), with its offer. If the offeror has completed FAR clause 52.212-3 at www.sam.gov, then the offeror does not need to provide a completed copy with its offer.
(xi) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition.
(xii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.
(xiii) Responses to this solicitation must include clear and convincing evidence of the offeror’s capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price proposal must include the labor categories, an estimate of the number of hours required for each labor category, fully loaded fixed hourly rate or each labor category, breakdown and rationale for other direct costs or materials, and the total amount.
The Unique Entity ID from SAM.gov, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.
Allquotationsmust be received by December 10, 2024 at 12:00 PM Eastern Time and must reference solicitation number 75N95025Q00023. Responses must be submitted electronically to Rashiid Cummins, Contract Specialist, at rashiid.cummins@nih.gov
Fax responses will not be accepted.
Attachments
| File | Type | Posted |
|---|---|---|
| D-Attachment-SOW Long read sequencing services revised 12.9.2024.pdf | ||
| D-Attachment-Questions.pdf | ||
| D-Attachment-SOW Long read sequencing services.pdf | ||
| D-Attachment-FAR_52.204-26 (Oct 2020).pdf | ||
| D-Attachment-FAR_52.204-24 (Nov 2021).pdf | ||
| D-Attachment-Invoicing Instructions With IPP_Updated.pdf | ||
| D-Attachment-FAR 52.212-4 Addendum.pdf | ||
| D-Attachment-FAR 52.212-5 (Nov 2024) FILLABLE 11-12-2024.pdf |
Notice history
| Notice | Type | Posted |
|---|---|---|
| Long read sequencing services | Award Notice | |
| Long read sequencing services | Solicitation | |
| SOURCES SOUGHT: Long read sequencing services | Pre-Solicitation |
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