Attachment No. 6 Additional Technical Proposal Instructions..pdf

NIH-NIMH-75N95022R00031 Attachment No. 6

Additional Technical Proposal Instructions

1. Offeror’s proposal must include a technical proposal in response to General Task Area 1 of the

Statement of Work and at least one of General Task Area 2 or General Task Area 3 or General

Task Area 4. In addition, the offeror’s proposal must include a technical proposal in response to General Task Area 5 and/or 6. General Task Area 7 is optional. In addition to General Task

Areas, Offerors must also include, in a clearly labeled separate section of their proposal, a separate response for each Sample Task Order for the respective General Task Areas in which they proposed. Sample Task Orders are included in this Solicitation as Attachments 8-9.

2. All offerors must submit a task order proposal for Task Order 1 – Manual of Operations and Sample Task Order 1 – Manual of Operations. Task Order 1 reflects the IDIQ minimum.

3. All offerors must submit a proposal for at least one of the following:

A. Task Order 2 - Large-Scale Single-cell Transcriptome Sequencing, or

B. Task Order 3 - Large-Scale Single-cell Epigenome Sequencing, or

C. Task Order 4 – Large-Scale Single-cell Multi-omics Sequencing.

and at least one of the following:

D. Task Order 5 - Bulk Tissue Transcriptome and Epigenome Sequencing, or

E. Task Order 6 - Whole Genome and Exome Sequencing, Task Order 7 - Novel Omics Sequencing is optional and does not satisfy the above requirements.

4. Should an offeror propose a subcontractor, all responses provided in the general proposal section of the offeror’s proposal must include the subcontractor’s responses to those areas as well.

5. Sample Proposal Format

A. General Task Area Proposal (See Statement of Work)

a. Technical Proposal (Cover Page) – Not to exceed 25 pages (See Section L)

i. Technical Discussions

1. Mandatory Qualification Criteria (Pages 109-110). The mandatory qualification criteria establish conditions that must be met at the time of proposal.

2. Statement of Work (Pages 86-87)

a. Address general task areas in which offeror is proposing

(See Attachment 3 – Statement of Work)

b. Address maximum capacity for each task area in which offeror is proposing

c. Address the turnaround time from receipt of samples for each task area

d. Address the data processing/bioinformatics pipeline for each task area

3. Personnel (Page 87-88)

ii. Other Considerations (Page 89)

iii. Electronic and Information Technology Accessibility, Section 508

Compliance (Page 90-92)

b. Business Proposal (Cover Page)

i. General Price/Cost List (Page 82-83)

1. Identify max capacity with associated cost/price points up to max capacity (refer to item A.a.i.1.b. above), page 86.

2. Note: The government reserves the right to issue cost reimbursement task orders. Requirements included on pages

105-106 will be required when submitting a proposal in response to future cost reimbursement Request for Task Order

Proposals (TO-RFP).

3. Reference Salary Rate Limitation, page 99.

ii. Small Business Subcontracting Plan for max IDIQ cost identified in solicitation (if other than small business) (Page 99-101)

iii. Mentor-Protégé Program, HHSAR 352.219-70 (Page 101-102)

1. If not applicable, state not applicable

iv. HUBZone Small Business Concerns (Page 102)

v. Total Compensation Plan (Page 102-103)

vi. Other Administrative Data (Page 103)

1. Property (Page 103-104)

2. Submission of Electronic Funds transfer Information with Offer, FAR Clause 52.232-38 (JULY 2013) (Page 104-105)

3. Financial Capacity (Page 105)

4. Adequate Accounting System (Page 105)

5. Facilities Capital Cost of Money, FAR 52.215-16 (June 2003)

(Page 106)

vii. Qualifications of the Offeror (Page 107)

viii. Subcontractors (Page 107-108)

ix. Proposer’s Annual Financial Report (Page 108)

x. Travel Costs/Travel Policy (Page 108)

xi. Past Performance (Page 70)

xii. Information Systems Security (Page 73-85)

B. Sample Task Order Proposal – Task Area 1 – Manual of Operations

a. Technical Proposal – Not to exceed 20 pages (See Section L)

i. Statement of Work (Pages 86-87)

1. Address specific task areas as identified in the request for task order proposal (TO-RFP) (Attachment 8)

b. Business Proposal

i. Price Proposal based off minimum identified in the solicitation

C. Sample Task Order Proposal (addresses task areas 2-7 as applicable – one for each task area)

a. Technical Proposal - Not to exceed 30 pages for each sample task area (See

Section L)

i. Statement of Work (Pages 86-87)

1. Address specific task areas as identified in the request for task order proposal (TO-RFP) (Attachments 9, as applicable)

ii. Personnel (Page 87-88)

iii. Other Considerations (Page 89)

b. Business Proposal (addresses costs for task areas 2-6 as applicable)

i. Cost reimbursement breakdown for specific task area

1. Supporting price documentation