A23 Attachment 2a Assay Testing Requirements.xlsx
XLSX spreadsheet 22 KB Posted
- Solicitation number
- 75N992-25-SN-104
About this file
The file is an Excel spreadsheet (A23 Attachment 2a Assay Testing Requirements) that details comprehensive assay testing specifications for a clinical research project. The spreadsheet outlines detailed technical requirements for whole exome sequencing, including coverage metrics, gene number capabilities, and performance benchmarks. Key specifications include multiple performance tiers for coverage (>100x, >150x, >200x), gene count capabilities (ranging from 15k to 20k genes), and preferred testing parameters involving sequencing depth and gene range. The document appears to be a technical specification sheet supporting the ADAPT Contract Research Organization Support Services solicitation (75N992-25-SN-104) issued by the Department of Health and Human Services National Institutes of Health, with proposals due on April 11, 2025.
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| A23 75N99225R00005 Conformed 041525.pdf | ||
| A23 Attachment 2 Assay Testing Worksheet.xlsx | XLSX spreadsheet | |
| A23 75N99225R00005 AMD 0003.pdf | ||
| A23 Attachment 2a Assay Testing Requirements.xlsx | XLSX spreadsheet | |
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| A24 Q_A Consolidated List 75N99225R00005 FINAL.xlsx | XLSX spreadsheet | |
| A23 75N99225R00005 AMD 0002.pdf | ||
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| A23 Attachment ARPA-H-MAI-24-01-03 AMD 02.pdf | ||
| A23 75N99225R00005 AMD 0001.pdf | ||
| A23 75N99225R00005 Conformed AMD 0001 032825.pdf | ||
| A23 75N99225R00002 Final.pdf | ||
| A23 Attachment 3 HHS Subcontracting Plan Template.docx | DOCX document | |
| A23 Attachment 2 Assay Testing Worksheet.xlsx | XLSX spreadsheet | |
| A23 Attachment 1 Price Template.xlsx | XLSX spreadsheet |
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Text version
Sheet1
| Type of assay | Assay Name and details (manufacturer, version) | Name of entity that is performing the test | CLIA-certified lab (yes/no; provide license number) | Coverage (e.g., 1000x) | Number of genes (maximum capability) | Average Turnaround Time (days) | ||||||
| Meets | Preferred | Strongly Preferred | Meets | Preferred | Strongly Preferred | Meets | Preferred | Strongly Preferred | ||||
| whole exome sequencing | Y/N | >100x | >150x | >200x | >15k | >16.5k | >20k | <14 days | <12 days | <8 days | ||
| whole transcriptome sequencing | Y/N | 50M reads | >75M reads | >100M reads | >15k | >16.5k | >20k | <14 days | <12 days | <8 days | ||
| ctDNA-seq | Y/N | >500x | >1000x | >2000x | >500 | >1,000 | >15,000 | <14 days | <12 days | <8 days | ||
| ctDNA methylome | N/A (RUO allowed) | >500x | >1000x | >2000x | >500 | >1,000 | >15,000 | <14 days | <12 days | <8 days | ||
| cfMeDIP-seq*** | N/A (RUO allowed) | >500x | >1000x | >2000x | >500 | >1,000 | >15,000 | <35 days | <28 days | <14 days | ||
| M= million | ||||||||||||
| k= thousand | ||||||||||||
| N/A= not applicable |
| *RUO = Research Use Only |
| **Average Turnaround Time is based on Offeror receipt of sample |
| ***Optional; Not required for table completion |
File details come from the government source that posted it. Updated .