A23 Attachment 2a Assay Testing Requirements.xlsx
XLSX spreadsheet 17 KB Posted
- Solicitation number
- 75N992-25-SN-104
About this file
Attachment 2a is an Excel spreadsheet detailing assay testing requirements for a federal contract opportunity. The document outlines technical specifications for whole exome sequencing, including performance metrics such as mean coverage, number of genes, and turnaround time. The spreadsheet provides comparative evaluation criteria across multiple dimensions, including coverage levels (>100x, >150x, >200x), gene number capabilities (>15k, >16.5k, >20k), and additional technical parameters like gene count (>500, >1,000, >15,000).
The associated federal contract opportunity is the ADAPT Contract Research Organization Support Services solicitation (75N992-25-SN-104) issued by the Department of Health and Human Services National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H). The solicitation anticipates a single award contract for precision therapy research support services. Key dates include a questions deadline of April 3, 2025, and a proposal submission deadline of April 11, 2025. The opportunity is a combined synopsis/solicitation for commercial services, with all necessary proposal information included in the Request for Proposals (RFP) and its attachments.
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| A23 Attachment 2a Assay Testing Requirements.xlsx | XLSX spreadsheet | |
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Text version
Sheet1
| Type of assay | Assay Name and details (manufacturer, version) | Name of entity that is performing the test | CLIA-certified lab (yes/no; provide license number) | Mean Coverage (e.g., 1000x) | Number of genes (maximum capability) | Average Turnaround Time (days) | ||||||
| Meets | Preferred | Strongly Preferred | Meets | Preferred | Strongly Preferred | Meets | Preferred | Strongly Preferred | ||||
| whole exome sequencing | Y/N | >100x | >150x | >200x | >15k | >16.5k | >20k | <14 days | <12 days | <8 days | ||
| whole transcriptome sequencing | Y/N | 50M reads | >75M reads | >100M reads | >15k | >16.5k | >20k | <14 days | <12 days | <8 days | ||
| ctDNA-seq | Y/N | >500x | >1000x | >2000x | >500 | >1,000 | >15,000 | <14 days | <12 days | <8 days | ||
| ctDNA methylome | N/A (RUO allowed) | >500x | >1000x | >2000x | >500 | >1,000 | >15,000 | <14 days | <12 days | <8 days | ||
| cfMeDIP-seq*** | N/A (RUO allowed) | >500x | >1000x | >2000x | >500 | >1,000 | >15,000 | <35 days | <28 days | <14 days | ||
| M= million | ||||||||||||
| k= thousand | ||||||||||||
| N/A= not applicable |
| *RUO = Research Use Only |
| **Average Turnaround Time is based on Offeror receipt of sample |
| ***Optional; Not required for table completion |
File details come from the government source that posted it. Updated .