Methanol SDS.pdf

SAFETY DATA SHEET

Creation Date 27-Apr-2009 Revision Date 13-Oct-2023 Revision Number 10

1. Identification Product Name Methanol

Cat No. : A412-1; A412-4; A412-4LC; A412-20; A412-200; A412200-001;

A412-200LC; A412-500; A412CU-1300; A412P-4; A412SK-4;

A412FB-19; A412FB-50; A412FB-115; A412FB-200; A412POP-19;

A412POPB-200; A412RB50; A412RB-115; A412RB-200; A412RS-19;

A412RS-28; A412RS-50; A412RS-115; A412RS-200; A412SS-115;

A412SS-19; XXA412ETU200LI; NC1282211; XXA412ETWD200LI;

NC1380933; A412RS-1350ASME; NC1561769; A412RS200ASME;

NC1568698; NC1822351; XXA412ETU20LI; A412ETRS1350ASM;

NC1871449; A412RS1350; NC1882599; XXA412ET200LI; NC1911795;

A412RS1250; NC2012101; NC2047038; NC2165479; NC2312993

CAS No 67-56-1 Synonyms Methyl alcohol

Recommended Use Laboratory chemicals.

Uses advised against .

Details of the supplier of the safety data sheet

2. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)

Company Fisher Scientific Company One Reagent Lane Fair Lawn, NJ 07410 Tel: (201) 796-7100

Emergency Telephone Number CHEMTRECÒ, Inside the USA: 800-424-9300 CHEMTRECÒ, Outside the USA: 001-703-527-3887

Acute oral toxicity Category 3 Acute dermal toxicity Category 3 Acute Inhalation Toxicity - Vapors Category 3 Specific target organ toxicity (single exposure) Category 1 Target Organs - Optic nerve, Central nervous system (CNS).

Flammable liquids

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Category 2

Methanol Revision Date 13-Oct-2023

Label Elements

Signal Word Danger

Hazard Statements Highly flammable liquid and vapor Causes damage to organs Causes damage to organs through prolonged or repeated exposure Toxic if swallowed, in contact with skin or if inhaled

Precautionary Statements Prevention Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Wear protective gloves/protective clothing/eye protection/face protection Use only outdoors or in a well-ventilated area Do not breathe dust/fume/gas/mist/vapors/spray Keep away from heat/sparks/open flames/hot surfaces. - No smoking Keep container tightly closed Ground/bond container and receiving equipment Use explosion-proof electrical/ventilating/lighting equipment Use only non-sparking tools Take precautionary measures against static discharge Keep cool Response IF exposed: Call a POISON CENTER or doctor/physician Inhalation IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Call a POISON CENTER or doctor/physician Skin Call a POISON CENTER or doctor/physician if you feel unwell Wash contaminated clothing before reuse IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower Ingestion IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician Rinse mouth Fire In case of fire: Use CO2, dry chemical, or foam for extinction Storage Store locked up Store in a well-ventilated place. Keep container tightly closed Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC)

Other hazards

Specific target organ toxicity - (repeated exposure) Category 1 Target Organs - Kidney, Liver, spleen, Blood.

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Poison, may be fatal or cause blindness if swallowed. Vapor harmful. CANNOT BE MADE NON-POISONOUS.

WARNING. Reproductive Harm - https://www.p65warnings.ca.gov/.

3. Composition/Information on Ingredients

Component CAS No Weight % Methyl alcohol 67-56-1 >95

4. First-aid measures

General Advice Immediate medical attention is required. Show this safety data sheet to the doctor in attendance.

Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

Immediate medical attention is required.

Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.

Inhalation Remove to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.

Immediate medical attention is required.

Ingestion Do NOT induce vomiting. Call a physician or poison control center immediately.

Most important symptoms and effects

Difficulty in breathing. May cause blindness: Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting

Notes to Physician Treat symptomatically

5. Fire-fighting measures

Suitable Extinguishing Media Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam. Water mist may be used to cool closed containers.

Unsuitable Extinguishing Media Water may be ineffective

Flash Point 9.7 °C / 49.5 °F

Method - CC (closed cup) Abel-Pensky (DIN 51755) Directive 84/449/EEC, A.9

Autoignition Temperature 455 °C / 851 °F

Explosion Limits Upper 31.00 vol % Lower 6.0 vol % Sensitivity to Mechanical Impact No information available Sensitivity to Static Discharge No information available

Specific Hazards Arising from the Chemical Flammable. Risk of ignition. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back.

Containers may explode when heated. Vapors may form explosive mixtures with air.

Hazardous Combustion Products Carbon monoxide (CO). Formaldehyde.

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Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors.

NFPA

6. Accidental release measures Personal Precautions Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Use personal protective equipment as required. Ensure adequate ventilation. Remove all sources of ignition. Take precautionary measures against static discharges.

Environmental Precautions Should not be released into the environment. See Section 12 for additional Ecological Information.

Methods for Containment and Clean Up

Soak up with inert absorbent material. Keep in suitable, closed containers for disposal.

Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment.

7. Handling and storage Handling Wear personal protective equipment/face protection. Do not breathe mist/vapors/spray. Do not get in eyes, on skin, or on clothing. Use only under a chemical fume hood. Do not ingest. If swallowed then seek immediate medical assistance. Keep away from open flames, hot surfaces and sources of ignition. Use only non-sparking tools. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded.

Take precautionary measures against static discharges.

Storage. Keep container tightly closed in a dry and well-ventilated place. Keep away from open flames, hot surfaces and sources of ignition. Flammables area. Incompatible Materials.

Strong oxidizing agents. Strong acids. Acid anhydrides. Acid chlorides. Strong bases.

Metals. Peroxides.

8. Exposure controls / personal protection Exposure Guidelines

Health

Flammability

Instability

Physical hazards N/A

Component ACGIH TLV OSHA PEL NIOSH Mexico OEL (TWA) Methyl alcohol TWA: 200 ppm

STEL: 250 ppm Skin

(Vacated) TWA: 200 ppm (Vacated) TWA: 260 mg/m3

(Vacated) STEL: 250 ppm (Vacated) STEL: 325 mg/m3

Skin TWA: 200 ppm

TWA: 260 mg/m3

IDLH: 6000 ppm TWA: 200 ppm

TWA: 260 mg/m3

STEL: 250 ppm STEL: 325 mg/m3

TWA: 200 ppm STEL: 250 ppm

Legend

ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and Health Administration NIOSH: NIOSH - National Institute for Occupational Safety and Health

Engineering Measures Use only under a chemical fume hood. Use explosion-proof electrical/ventilating/lighting equipment. Ensure that eyewash stations and safety showers are close to the workstation location.

Personal Protective Equipment

Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard

EN166.

Skin and body protection

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Wear appropriate protective gloves and clothing to prevent skin exposure.

9. Physical and chemical properties Physical State Liquid Appearance Colorless Odor Alcohol-like Odor Threshold No information available pH Not applicable Melting Point/Range -98 °C / -144.4 °F Boiling Point/Range 64.7 °C / 148.5 °F @ 760 mmHg Flash Point 9.7 °C / 49.5 °F

Method - CC (closed cup) Abel-Pensky (DIN 51755) Directive 84/449/EEC, A.9

Evaporation Rate 5.2 (ether = 1) Flammability (solid,gas) Not applicable Flammability or explosive limits

Upper 31.00 vol % Lower 6.0 vol %

Vapor Pressure 128 hPa @ 20 °C Vapor Density 1.11 Specific Gravity 0.791 Solubility Miscible with water Partition coefficient; n-octanol/water No data available Autoignition Temperature 455 °C / 851 °F Decomposition Temperature No information available Viscosity 0.55 cP at 20 °C Molecular Formula C H4 O Molecular Weight 32.04 VOC Content(%) 100 Surface tension 0.02255 N/m @ 20°C

10. Stability and reactivity

Reactive Hazard None known, based on information available

Stability Stable under normal conditions.

Conditions to Avoid Incompatible products. Heat, flames and sparks. Keep away from open flames, hot surfaces and sources of ignition.

Incompatible Materials Strong oxidizing agents, Strong acids, Acid anhydrides, Acid chlorides, Strong bases, Metals, Peroxides

Hazardous Decomposition Products Carbon monoxide (CO), Formaldehyde

Hazardous Polymerization Hazardous polymerization does not occur.

Hazardous Reactions None under normal processing.

11. Toxicological information Acute Toxicity

Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Recommended Filter type: low boiling organic solvent. Type AX. Brown. conforming to EN371.

Hygiene Measures

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When using do not eat, drink or smoke. Provide regular cleaning of equipment, work area and clothing.

Product Information Component Information

Component LD50 Oral LD50 Dermal LC50 Inhalation Methyl alcohol LD50 = 1187 – 2769 mg/kg (Rat) LD50 = 17100 mg/kg ( Rabbit ) LC50 = 128.2 mg/L ( Rat ) 4 h

Toxicologically Synergistic Products

Carbon tetrachloride

Delayed and immediate effects as well as chronic effects from short and long-term exposure

Irritation May cause skin and eye irritation

Sensitization No information available

Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.

Component CAS No IARC NTP ACGIH OSHA Mexico Methyl alcohol 67-56-1 Not listed Not listed Not listed Not listed Not listed

Mutagenic Effects No information available

Reproductive Effects No information available.

Developmental Effects Component substance is listed on California Proposition 65 as a developmental hazard.

Teratogenicity No information available.

STOT - single exposure Optic nerve Central nervous system (CNS) STOT - repeated exposure Kidney Liver spleen Blood

Aspiration hazard No information available

Symptoms / effects,both acute and delayed

May cause blindness: Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting

Endocrine Disruptor Information No information available

Other Adverse Effects The toxicological properties have not been fully investigated.

12. Ecological information Ecotoxicity

Component Freshwater Algae Freshwater Fish Microtox Water Flea Methyl alcohol Not listed Pimephales promelas: LC50

> 10000 mg/L 96h EC50 = 39000 mg/L 25 min EC50 = 40000 mg/L 15 min EC50 = 43000 mg/L 5 min

EC50 > 10000 mg/L 24h

Persistence and Degradability Persistence is unlikely based on information available.

Bioaccumulation/ Accumulation No information available.

Mobility Will likely be mobile in the environment due to its volatility.

Component log Pow Methyl alcohol -0.74

13. Disposal considerations Waste Disposal Methods Should not be released into the environment.

Component RCRA - U Series Wastes RCRA - P Series Wastes Methyl alcohol - 67-56-1 U154 -

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14. Transport information

DOT

UN-No UN1230 Proper Shipping Name METHANOL Hazard Class 3 Packing Group II

TDG

UN-No UN1230 Proper Shipping Name METHANOL Hazard Class 3 Subsidiary Hazard Class 6.1 Packing Group II

IATA

UN-No UN1230 Proper Shipping Name METHANOL Hazard Class 3 Subsidiary Hazard Class 6.1 Packing Group II

IMDG/IMO

UN-No UN1230 Proper Shipping Name METHANOL Hazard Class 3 Subsidiary Hazard Class 6.1 Packing Group II

15. Regulatory information

United States of America Inventory

Component CAS No TSCA TSCA Inventory notification - Active-Inactive

TSCA - EPA Regulatory Flags

Methyl alcohol 67-56-1 X ACTIVE -

Legend:

TSCA US EPA (TSCA) - Toxic Substances Control Act, (40 CFR Part 710) X - Listed '-' - Not Listed

TSCA - Per 40 CFR 751, Regulation of Certain Chemical Substances & Mixtures, Under TSCA Section 6(h) (PBT)

Not applicable

TSCA 12(b) - Notices of Export Not applicable

International Inventories Canada (DSL/NDSL), Europe (EINECS/ELINCS/NLP), Philippines (PICCS), Japan (ENCS), Japan (ISHL), Australia (AICS), China (IECSC), Korea

(KECL).

Component CAS No DSL NDSL EINECS PICCS ENCS ISHL AICS IECSC KECL Methyl alcohol 67-56-1 X - 200-659-6 X X X X X KE-23193

KECL - NIER number or KE number (http://ncis.nier.go.kr/en/main.do)

U.S. Federal Regulations

SARA 313

Component CAS No Weight % SARA 313 - Threshold

Values % Methyl alcohol 67-56-1 >95 1.0

SARA 311/312 Hazard Categories See section 2 for more information

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CWA (Clean Water Act) Not applicable

Clean Air Act Component HAPS Data Class 1 Ozone Depletors Class 2 Ozone Depletors

Methyl alcohol X -

OSHA - Occupational Safety and Health Administration

Not applicable

CERCLA This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302)

Component Hazardous Substances RQs CERCLA EHS RQs

Methyl alcohol 5000 lb -

California Proposition 65 This product contains the following Proposition 65 chemicals.

Component CAS No California Prop. 65 Prop 65 NSRL Category

Methyl alcohol 67-56-1 Developmental - Developmental

U.S. State Right-to-Know Regulations

Component Massachusetts New Jersey Pennsylvania Illinois Rhode Island

Methyl alcohol X X X X X

U.S. Department of Transportation Reportable Quantity (RQ): Y DOT Marine Pollutant N DOT Severe Marine Pollutant N

U.S. Department of Homeland Security

This product does not contain any DHS chemicals.

Other International Regulations

Mexico - Grade Serious risk, Grade 3

Authorisation/Restrictions according to EU REACH

Component CAS No REACH (1907/2006) - Annex XIV - Substances Subject to Authorization

REACH (1907/2006) -

Annex XVII - Restrictions on Certain Dangerous Substances

REACH Regulation (EC 1907/2006) article 59 -

Candidate List of Substances of Very High

Concern (SVHC) Methyl alcohol 67-56-1 - Use restricted. See item

69.

(see link for restriction details) Use restricted. See item

75.

(see link for restriction details)

REACH links https://echa.europa.eu/substances-restricted-under-reach

Safety, health and environmental regulations/legislation specific for the substance or mixture

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Component CAS No OECD HPV Persistent Organic Pollutant

Ozone Depletion Potential

Restriction of Hazardous

Substances (RoHS) Methyl alcohol 67-56-1 Listed Not applicable Not applicable Not applicable

Contains component(s) that meet a 'definition' of per & poly fluoroalkyl substance (PFAS)?

Not applicable

Other International Regulations

Component CAS No Seveso III Directive

(2012/18/EC) -

Qualifying Quantities for Major Accident

Notification

Seveso III Directive

(2012/18/EC) -

Qualifying Quantities for Safety Report

Requirements

Rotterdam Convention (PIC)

Basel Convention (Hazardous Waste)

Methyl alcohol 67-56-1 500 tonne 5000 tonne Not applicable Not applicable

16. Other information Prepared By Regulatory Affairs

Thermo Fisher Scientific Email: EMSDS.RA@thermofisher.com

Creation Date 27-Apr-2009 Revision Date 13-Oct-2023 Print Date 13-Oct-2023 Revision Summary This document has been updated to comply with the US OSHA HazCom 2012 Standard replacing the current legislation under 29 CFR 1910.1200 to align with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS).

Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text

End of SDS

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