MSDS-0326C.pdf

SIGALD - 320331

The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the US and Canada

SAFETY DATA SHEET

Version 6.9 Revision Date 06/07/2021

Print Date 11/27/2021

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers

Product name : Hydrochloric acid

Product Number : 320331

Brand : SIGALD

Index-No. : 017-002-01-X

CAS-No. : 7647-01-0

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses : Laboratory chemicals, Synthesis of substances

1.3 Details of the supplier of the safety data sheet

Company : Sigma-Aldrich Inc.

3050 SPRUCE ST

ST. LOUIS MO 63103

UNITED STATES

Telephone : +1 314 771-5765

Fax : +1 800 325-5052

1.4 Emergency telephone

Emergency Phone # : 800-424-9300 CHEMTREC (USA) +1-703-

527-3887 CHEMTREC (International) 24

Hours/day; 7 Days/week

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)

Corrosive to Metals (Category 1), H290

Skin corrosion (Category 1B), H314

Serious eye damage (Category 1), H318

Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335

For the full text of the H-Statements mentioned in this Section, see Section 16.

2.2 GHS Label elements, including precautionary statements

Pictogram

Signal word Danger

Hazard statement(s)

H290 May be corrosive to metals.

H314 Causes severe skin burns and eye damage.

H335 May cause respiratory irritation.

Precautionary statement(s)

P234 Keep only in original container.

P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.

P264 Wash skin thoroughly after handling.

P271 Use only outdoors or in a well-ventilated area.

P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.

P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor.

P305 + P351 + P338 +

P310

IF IN EYES: Rinse cautiously with water for several minutes.

Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.

P363 Wash contaminated clothing before reuse.

P390 Absorb spillage to prevent material damage.

P403 + P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

P406 Store in corrosive resistant container with a resistant inner liner.

P501 Dispose of contents/ container to an approved waste disposal plant.

2.3 Hazards not otherwise classified (HNOC) or not covered by GHS - none

SECTION 3: Composition/information on ingredients

3.2 Mixtures

Component Classification Concentration

Hydrochloric Acid

CAS-No.

EC-No.

Index-No.

Registration number

7647-01-0

231-595-7

017-002-01-X

01-2119484862-27-

XXXX

Met. Corr. 1; Skin Corr.

1B; Eye Dam. 1; STOT SE

3; H290, H314, H318, H335

Concentration limits:

>= 0.1 %: Met. Corr. 1, H290; >= 25 %: Skin

Corr. 1B, H314; 10 - < 25

%: Skin Irrit. 2, H315; 10

- < 25 %: Eye Irrit. 2, H319; >= 10 %: STOT SE

3, H335;

>= 30 - < 50

For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice

First aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. Call in physician.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

In case of eye contact

After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist.

Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section

2.2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Hydrogen chloride gas

Not combustible.

Ambient fire may liberate hazardous vapours.

5.3 Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

5.4 Further information

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.Cover drains. Collect, bind, and pump off spills.

Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ). Dispose of properly. Clean up affected area.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions

No metal containers.

Tightly closed.

Storage class (TRGS 510): 8B: Non-combustible, corrosive hazardous materials

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

Component CAS-No. Value Control parameters

Basis

Hydrochloric Acid

7647-01-0

C 2 ppm

USA. ACGIH Threshold Limit

Values (TLV)

Remarks Not classifiable as a human carcinogen

C 5 ppm

7 mg/m3

USA. NIOSH Recommended

Exposure Limits C 5 ppm

7 mg/m3

USA. Occupational Exposure

Limits (OSHA) - Table Z-1

Limits for Air Contaminants C 5 ppm

7 mg/m3

USA. OSHA - TABLE Z-1 Limits for Air Contaminants -

1910.1000 PEL 0.3 ppm

0.45 mg/m3

California permissible exposure limits for chemical contaminants (Title 8, Article

107) C 2 ppm

California permissible exposure limits for chemical contaminants (Title 8, Article

107)

8.2 Exposure controls

Appropriate engineering controls

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0.4 mm

Break through time: 480 min

Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)

Splash contact

Material: Nitrile rubber

Minimum layer thickness: 0.11 mm

Break through time: 69 min

Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374

If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Body Protection protective clothing

Respiratory protection required when vapours/aerosols are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

a) Appearance Form: liquid

Color: light yellow

b) Odor pungent

c) Odor Threshold No data available

d) pH No data available

e) Melting point/freezing point

-30 °C (-22 °F)

f) Initial boiling point and boiling range

> 100 °C > 212 °F

g) Flash point ()Not applicable

h) Evaporation rate No data available

i) Flammability (solid, gas)

No data available

j) Upper/lower flammability or explosive limits

No data available

k) Vapor pressure 226.636 hPa at 21.1 °C (70.0 °F)

546.596 hPa at 37.7 °C(99.9 °F)

l) Vapor density No data available

m) Relative density No data available

n) Water solubility soluble

o) Partition coefficient:

n-octanol/water

No data available

p) Autoignition temperature

Not applicable

q) Decomposition temperature

No data available

r) Viscosity No data available

s) Explosive properties No data available

t) Oxidizing properties No data available

9.2 Other safety information

SECTION 10: Stability and reactivity

10.1 Reactivity

No data available

10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.3 Possibility of hazardous reactions

No data available

10.4 Conditions to avoid

no information available

10.5 Incompatible materials

Bases, Amines, Alkali metals, Metals, permanganates, for example potassium permanganate, Fluorine, metal acetylides, hexalithium disilicideMetals

10.6 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture

Acute toxicity

Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.

Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract

Dermal: No data available

Skin corrosion/irritation

Mixture causes burns.

Serious eye damage/eye irritation

Mixture causes serious eye damage. Risk of blindness!

Respiratory or skin sensitization

No data available

Germ cell mutagenicity

No data available

Carcinogenicity

IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

NTP: No ingredient of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.

OSHA: No component of this product present at levels greater than or equal to 0.1% is on OSHA’s list of regulated carcinogens.

Reproductive toxicity

Specific target organ toxicity - single exposure

Mixture may cause respiratory irritation.

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

11.2 Additional Information

RTECS: MW4025000

Other dangerous properties can not be excluded.

Handle in accordance with good industrial hygiene and safety practice.

Components

Acute toxicity

Oral: No data available

Inhalation: Cough Difficulty in breathing

Inhalation: absorption

Inhalation: Corrosive to respiratory system.

Symptoms: mucosal irritations, Cough, Shortness of breath, Inhalation may lead to the formation of oedemas in the respiratory tract., Possible damages:, damage of respiratory tract, tissue damage

Dermal: No data available

Skin corrosion/irritation

Skin - reconstructed human epidermis (RhE)

Result: Corrosive

(OECD Test Guideline 431)

Serious eye damage/eye irritation

Eyes - Bovine cornea

Result: Corrosive

(OECD Test Guideline 437)

Respiratory or skin sensitization

Maximization Test - Guinea pig

Result: negative

(OECD Test Guideline 406)

Germ cell mutagenicity

Test Type: Chromosome aberration test in vitro

Test system: Chinese hamster ovary cells

Result: Conflicting results have been seen in different studies.

Carcinogenicity

Carcinogenicity - Did not show carcinogenic effects in animal experiments. (IUCLID)

Reproductive toxicity

No data available

Specific target organ toxicity - single exposure

May cause respiratory irritation.

The substance or mixture is classified as specific target organ toxicant, single exposure, category 3 with respiratory tract irritation.

Acute inhalation toxicity - mucosal irritations, Cough, Shortness of breath, Inhalation may lead to the formation of oedemas in the respiratory tract., Possible damages:, damage of respiratory tract, tissue damage

Specific target organ toxicity - repeated exposure

The substance or mixture is not classified as specific target organ toxicant, repeated exposure.Aspiration hazard

No aspiration toxicity classification

SECTION 12: Ecological information

12.1 Toxicity

Mixture

No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Other adverse effects

No data available

Components

Hydrochloric Acid

No data available

Toxicity to fish LC50 - Gambusia affinis (Mosquito fish) - 282 mg/l - 96 h

Remarks: (IUCLID)

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product

Waste material must be disposed of in accordance with the national and local regulations.

Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself. See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

SECTION 14: Transport information

DOT (US)

UN number: 1789 Class: 8 Packing group: II

Proper shipping name: Hydrochloric acid

Reportable Quantity (RQ):

Poison Inhalation Hazard: No

IMDG

UN number: 1789 Class: 8 Packing group: II EMS-No: F-A, S-B

Proper shipping name: HYDROCHLORIC ACID

IATA

UN number: 1789 Class: 8 Packing group: II

Proper shipping name: Hydrochloric acid

SECTION 15: Regulatory information

SARA 302 Components

This material does not contain any components with a section 302 EHS TPQ.

SARA 313 Components

The following components are subject to reporting levels established by SARA Title III, Section 313:

CAS-No.

Revision Date

2013-02-08

SARA 311/312 Hazards

No SARA Hazards

Massachusetts Right To Know Components

CAS-No.

No components are subject to the Massachusetts Right to Know Act.

Pennsylvania Right To Know Components water CAS-No.

7732-18-5

Hydrochloric Acid 7647-01-0

New Jersey Right To Know Components water CAS-No.

7732-18-5

Hydrochloric Acid 7647-01-0

SECTION 16: Other information

Further information

The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only.

The branding on the header and/or footer of this document may temporarily not visually match the product purchased as we transition our branding. However, all of the information in the document regarding the product remains unchanged and matches the product ordered. For further information please contact mlsbranding@sial.com.

Version: 6.9 Revision Date: 06/07/2021 Print Date: 11/27/2021