National Center for Advancing Translational Sciences

Bethesda, MD

Agency facts

Acronym
Office code
75N95C
Organization
Contract obligations
$99,163,322 In FY2025

Agency codes and contract spending come from SAM.gov/FPDS.

Contract obligations by fiscal year

Fiscal year Obligated
FY2027 To date $7,209,177
FY2026 $175,690,830
FY2025 $99,163,322
FY2024 $204,150,050
FY2023 $210,222,509

Top contractors by obligations

Rank Contractor Obligated, FY2026–FY2027 Share
1 Leidos Biomedical Research Inc. $110,793,221
2 Axle Informatics, LLC $39,662,713
3 Palantir Technologies Inc. $9,738,016
4 Kelly Services, Inc. $3,074,684
5 A P Ventures, LLC $2,698,351
6 The Mitre Corporation $2,266,210
7 Revvity Signals Software, Inc. $2,007,320
8 Gap Solutions, Inc. $1,822,232
9 Paragon Micro Inc. $1,106,080
10 Flywheel Data LLC $878,328

Top contract vehicles by obligations

Rank Vehicle Obligated, FY2026–FY2027 Share
1 Multiple Award Schedule (MAS) GSA Schedule run by GSA · 14 contractors $53,378,015
2 Solutioning With Holistic Analytics Restructured For The Enterprise (SHARE) BPA run by HHS · 1 contractor $9,738,016
3 Scientific, Operations, and Administrative Resources to the National Institutes of Health (SOAR) IDIQ run by HHS · 4 contractors $5,290,179
4 Chief Information Officer Commodities and Solutions (CIO-CS) GWAC run by HHS · 12 contractors $3,513,946
5 Solutions for Enterprise Wide Procurement V (SEWP V) GWAC run by NASA · 2 contractors $682,271

5 of 10 vehicles listed here. See the rest on GovTribe.

Contract opportunities

Notice Posted Due
Andrew+ Liquid Handling Robot or Brand Name Equal Solicitation · 75N95019Q00346
Service Contract for 22 Heracell 160i Incubators and 2 Steri-Cult Incubators Solicitation · 75N95019Q00320
Andrew+ Liquid Handling Robot or Brand Name Equal Pre-Solicitation · 75N95019Q00346
Whole Genome CRISPR Screen Solicitation · 75N95019Q00327
Small Molecule Target Deconvolution via radiolabelled small molecule-cellular protein interations Solicitation · 75N95019Q00324
Promega Kits and Reagents Solicitation · 75N95019Q00337
Ub-AML substrate for DUB3 project Solicitation · 75N95019Q00333
Testing of compounds in mouse pharmacokinetic experiments Solicitation · 75N95019Q00323
Supplements and Media for SelecT Automated Cell Culture System Solicitation · 75N95019Q00328
Custom Built Ibex Pro GPU to include NVIDIA Quadro RTX 8000 Ray Rracing GPU or Brand Name Equal Solicitation
Consolidation of MathLabs liceses Solicitation
Promega Kits and Reagents Pre-Solicitation · 75N95019Q00337
HTRF cAMP Gi Assay Kits Solicitation
CellTiter-Glo and P450-Glo assay systems Solicitation
Environmentally-controlled live cell transport devices Solicitation
Exploratory Studies for Characterization of Disease Phenotype in NGY1 Mutant Cortical Glutamatergic Neurons for the Therapeutic Development Branch (TDB) at the National Center for Advancing Translational Sciences (NCATS). Solicitation
1536 Source Plates for Labcyte Echo Instruments Solicitation · 75N95019Q00308
Ub-AML substrate for DUB3 project Pre-Solicitation · 75N95019Q00333
Supplements and Media for SelecT Automated Cell Culture System Pre-Solicitation · 75N95019Q00328
Whole Genome CRISPR Screen Pre-Solicitation · 75N95019Q00327
Acquisition of Ibex Pro GPU (ibep2b) Pre-Solicitation
Small Molecule Target Deconvolution via radiolabelled small molecule-cellular protein interations Pre-Solicitation · 75N95019Q00324
Testing of compounds in mouse pharmacokinetic experiments Pre-Solicitation · 75N95019Q00323
Service contract for 22 Heracell 160i incubators and 2 Steri-cult incubators Pre-Solicitation · 75N95019Q00320
1536 Source Plates for Labcyte Echo Instruments Pre-Solicitation · 75N95019Q00308
Mixed Gender Human Liver Microsomes for NCATS Tox21 program Solicitation · 75N95019Q00306
Instrument service plan for Nextseq 500 S/N NB501931 Solicitation · 75N95019Q00283
Small Molecule Modulators of iPSC-Derived Hepatocyte and Neuronal Calcium Signaling Solicitation · 75N95019Q00282
Development and Characterization of an NGLY1 Deficiency Disorder Human-on-a-Chip Model Solicitation · 75N95019Q00284
ImageXpress Environmental Control Upgrades Solicitation · 75N95019Q00281
Mixed Gender Human Liver Microsomes for NCATS Tox21 program Pre-Solicitation · 75N95019Q00293
Development and Characterization of an NGLY1 Deficiency Disorder Human-on-a-Chip Model Pre-Solicitation · 75N95019Q00284
Instrument service plan for Nextseq 500 S/N NB501931 Pre-Solicitation · 75N95019Q00283
Small Molecule Modulators of iPSC-Derived Hepatocyte and Neuronal Calcium Signaling Pre-Solicitation · 75N95019Q00282
ImageXpress Environmental Control Upgrades Pre-Solicitation · 75N95019Q00281
Show all 35

About this agency

The National Center for Advancing Translational Sciences (NCATS), a division of the National Institutes of Health within the Department of Health and Human Services, funds research and development contracts and grants focused on translating scientific discoveries into practical biomedical applications for disease treatment and diagnosis.

NCATS operates a substantial contract portfolio totaling 2,403 awards with a combined potential value of $1.16 billion across 609 distinct prime contractors since 2010. Recent activity shows 284 awards in 2022, 301 in 2023, 255 in 2024, 107 in 2025, and 125 year-to-date in 2026. The most recent recorded award date is 2026-09-30. Competitive concentration is highly fragmented by award count—the top five primes account for only 14 percent of recent awards—though moderately concentrated by potential value, with the top five representing 42 percent of combined spending. Axle Informatics, LLC dominates by both count and value, holding 58 awards worth $300.5 million combined potential value. Palantir Technologies Inc. ranks second with 37 awards valued at $146.3 million. The remainder of the active base consists of specialized research vendors and government scientific suppliers. Set-asides are minimal: 90 percent of awards carry no set-aside designation, 9 percent are small-business set-asides, and SDVOSB, WOSB, 8(a), and HUBZone designations each represent less than 1 percent of awards combined.

NCATS also administers a grant program with 1,231 total awards obligating $12.7 billion in federal dollars since 1979, distributed across 385 distinct recipients. Recent grant cadence was 91 awards in 2022, 126 in 2023, 114 in 2024, 94 in 2025, and 104 year-to-date in 2026, with the most recent award dated 2026-09-03. Grant competition is highly fragmented: the top five recipients by award count hold only 11 percent of recent grants, while by federal dollars obligated they account for just 5 percent. University of North Carolina at Chapel Hill, Icahn School of Medicine at Mount Sinai, and Regents of the University of Michigan lead by dollars obligated, each receiving over $140 million federally across their recent awards. Keystone Symposia on Molecular and Cellular Biology and Gordon Research Conferences rank highest by award count. Grants are structured predominantly as Project Grants (62 percent of awards) with a substantial Cooperative Agreement component (38 percent).

Recent contract opportunities and grant opportunities are not provided in the source data, so current solicitations cannot be identified.

Quick answers

What is National Center for Advancing Translational Sciences?

National Center for Advancing Translational Sciences (NCATS) is part of National Institutes of Health, Department of Health and Human Services.

How much does National Center for Advancing Translational Sciences spend on contracts?

Contracts funded by National Center for Advancing Translational Sciences and its offices obligated $99,163,322 in fiscal year 2025 and $696,435,886 in fiscal years 2023 through 2027.

Who are National Center for Advancing Translational Sciences's largest contractors?

The contractors National Center for Advancing Translational Sciences and its offices obligated the most to in fiscal years 2026 and 2027 are Leidos Biomedical Research Inc. ($110,793,221), Axle Informatics, LLC ($39,662,713) and Palantir Technologies Inc. ($9,738,016).

Which contract vehicles does National Center for Advancing Translational Sciences use most?

The contract vehicles National Center for Advancing Translational Sciences and its offices obligated the most through in fiscal years 2026 and 2027 are Multiple Award Schedule (MAS) ($53,378,015), Solutioning With Holistic Analytics Restructured For The Enterprise (SHARE) ($9,738,016) and Scientific, Operations, and Administrative Resources to the National Institutes of Health (SOAR) ($5,290,179). Orders through any contract vehicle obligated $62,686,963 in those years, 34% of its contract obligations.

What is National Center for Advancing Translational Sciences's latest contract opportunity?

The latest contract opportunity from National Center for Advancing Translational Sciences is Andrew+ Liquid Handling Robot or Brand Name Equal, solicitation, posted September 17, 2019.

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