University Of Louisville

The University of Louisville, through its Office of Research & Innovation Division, is a tax-exempt public research university and recipient of federal contracts, indefinite-delivery vehicles, and grants across a diverse portfolio spanning research, clinical services, and educational programs. As a prime contractor and grantee (89% of recent awards), it competes full-and-open without set-aside designations, operating as one of 102 U.S. institutions holding both Carnegie R1 and community-engagement classifications.

UofL's primary federal work divides between clinical physician services to the Department of Veterans Affairs and a substantial research footprint across the National Institutes of Health, National Science Foundation, and Defense Health Agency. The institution delivers concrete capabilities in specialized medical services—particularly radiology, anesthesiology, gynecology, thoracic surgery, vascular surgery, and general surgery—under single-award indefinite-delivery contracts with VISN 9. The largest active contract is the radiology WRVU (work relative value unit) services IDIQ awarded April 1, 2025, with a ceiling of $23.6 million through March 31, 2030; two delivery orders totaling $6.5 million have been issued against this vehicle. Anesthesiology services carry an $11.1 million ceiling through September 30, 2029. These contracts are firm fixed-price, perform at Louisville VA medical facilities, and employ no subcontractors—delivery is direct.

On the research side, UofL acts as prime recipient on federal grants from NIH institutes (National Institute of Allergy and Infectious Diseases, National Cancer Institute, National Heart Lung and Blood Institute, National Institute of General Medical Sciences, National Neurological Disorders and Stroke), NSF divisions, and the Defense Health Agency. Representative awards include a $2 million NIAID grant for novel antiviral therapeutics targeting arthritogenic alphaviruses (September 24, 2025), a $1.4 million NHLBI grant investigating emergency granulopoiesis in ventricular remodeling (September 15, 2025), and a $1.2 million NIGMS grant establishing a Nutrition and Metabolic Health Center COBRE (May 15, 2026). The institution also holds research infrastructure grants from NIH Office of the Director for vivarium monitoring systems and laboratory instrumentation, and participates in NSF manufacturing extension partnerships and regional innovation engines. UofL's educational programs include TRIO Student Support Services, NSF Graduate Research Fellowship administration, and behavioral health workforce training.

Customer concentration is diffuse across 167 agencies but anchors on NIH (301 awards), NSF (171 awards), and VISN 9 (159 awards with $193 million combined potential value). Top funding by dollars flows from NIAID ($228.7 million across 79 awards) and VISN 9 ($193 million across 159 awards). The recompete cliff in the next 24 months exposes 145 awards valued at $3.1 million to expiration and competition.

UofL's parent vehicle footprint includes a General Services Administration Basic Ordering Agreement (GS04B59133) anchoring 44 task orders worth $37.5 million, and multiple single-award VA IDIQs for clinical services. SCI-reported invoiced revenue on federal service contracts above the $150,000 threshold totaled $13.4 million across FY2022–FY2025 ($6.5 million in FY2022, $3 million in FY2023, $3.9 million in FY2025); median government-paid hourly rates on prime contracts ran $132.64/hr, with senior labor at the 90th percentile reaching $233.19/hr. The workforce trajectory shows 19.5 FTEs in FY2022, declining to zero in FY2024, then rising to 24.1 FTEs in FY2025—a pattern reflecting irregular large-grant activity rather than stable service operations. Across prime contracts, the institution performs delivery with no identified subcontractors on major clinical services work; sub-engagement on SCI-reportable contracts averaged zero percent of hours.

UofL acts as prime recipient and sub-recipient on collaborative NIH grants, partnering with La Jolla Institute for Immunology on immunogenomics sequencing, University of Florida on Zika antiviral development, Johns Hopkins University on endothelial barrier recovery research, and University of Washington on visual neuroscience. These arrangements position UofL as both independent research performer and specialist contributor to larger multi-institutional consortia. The institution receives sub-awards through state health agencies (Kentucky Cabinet for Health Services) for Ryan White HIV/AIDS Program Parts A and B, and Kentucky rural health transformation initiatives, and operates as a sub-recipient on NSF I-Corps teams and Mid-South Hub activities. Its corporate structure is singular; it is the parent entity named in all identified awards.