The Methodist Hospital Research Institute
Houston, TX Part of The Methodist Hospital
- UEI
- XJUCJAYJWYV1
- CAGE
- 4AGX4
- Primary NAICS
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- SAM.gov registration
- Active through
Company facts
- Self-certified in SAM.gov
- Entity structure
- Corporate Entity (Tax Exempt)
- Corporate family
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-
Parent
The Methodist Hospital · Houston, TX
LNMBMFMATCL1
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Parent
The Methodist Hospital · Houston, TX
LNMBMFMATCL1
- SAM.gov registration date
- Physical address
- 6565 Fannin St d200, Houston, TX 77030, USA
- Website
- houstonmethodist.org
- Employees
- 10K-50K
- Estimated annual revenue
- $1B-$10B
- Industry
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- Health Care
- Health Care Equipment & Services
- Health Care Providers & Services
- Health Care Services
- SIC code
- 80 Health Services
- Profiles
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Contract obligations by fiscal year
| Fiscal year | Obligated |
|---|---|
| FY2027 To date | $0 |
| FY2026 | $6,103,473 |
Top agencies by obligations
| Rank | Agency | Obligated, FY2026–FY2027 | Share |
|---|---|---|---|
| 1 | Department of Health and Human Services | $6,103,473 |
Contract awards
Latest 5 listed here. See the rest on GovTribe.
Contract subawards
| Prime contractor | Prime award | Amount | Awarded |
|---|---|---|---|
| Travel Concepts Inc. | 75N91025F00001 | $1,122,335 | |
| Not on record | 75N91023P00542 | $84,279 | |
| University Of Montana | 75N93019C00045 | $356,698 |
Grant awards
Latest 5 listed here. See the rest on GovTribe.
Grant subawards
| Prime recipient | Prime award | Amount | Awarded |
|---|---|---|---|
| University Of Pittsburgh - Of The Commonwealth System Of Higher Education | R01DE033908 | $177,300 | |
| Albert Einstein College Of Medicine | U19AI181977 | $93,632 | |
| University Of Pittsburgh - Of The Commonwealth System Of Higher Education | R21AI200033 | $87,528 | |
| Case Western Reserve University | R01HL167199 | $38,270 | |
| The Leland Stanford Junior University | R01HL168188 | $163,280 |
Latest 5 listed here. See the rest on GovTribe.
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About the company
The Methodist Hospital Research Institute, a nonprofit biomedical research organization and division of The Methodist Hospital in Houston, Texas, operates as a federal grant recipient and Other Transaction Agreement (OTA) prime—not a traditional contractor—conducting mechanism-driven translational research in immunology, molecular oncology, regenerative medicine, and infectious disease with an NIH OTA awarded September 2026 (SMART-CURE | 1CURE, $23.3 million ceiling through September 2031).
The institute's federal footprint is almost entirely grant-funded. The National Institutes of Health—particularly the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Heart Lung and Blood Institute—dominates the customer concentration, together with the Defense Health Agency. Recent representative grants include a $2.71 million NIAID award for self-adjuvanted mRNA vaccine development targeting tuberculosis (Allergy and Infectious Diseases Research, CFDA 93.855); a $1.4 million Defense Health Agency grant for novel therapeutics targeting DNA damage in atypical burns (Military Medical Research and Development, CFDA 12.420); and a $1.03 million National Eye Institute award for mitochondrial cell therapy applied to age-related macular degeneration (Vision Research, CFDA 93.867). Smaller exploratory work includes NSF-funded engineering grants in robotic nursing assistance and remote physical examination technologies, and NIH-funded workshops on neuroregeneration and biostatistics. The institute also holds a position on the Joint PEO Chemical and Biological Defense Other Transaction IDV (ANTAEUS, awarded October 2023, $10.5 million ceiling) for monoclonal antibody discovery and engineering.
Activity data shows 482 total awards (prime and sub combined) across 47 customer agencies, with 350 prime positions (73%) and 132 sub-awards (27%). The portfolio has grown from 37 awards in 2022 to 63 in 2024, with 62 awards projected to complete in the next twenty-four months. The institute operates across the Texas Medical Center in Houston (primary address 6565 Fannin Street) with affiliated Methodist hospitals including Willowbrook, Sugarland, San Jacinto, and West Houston. Service Contract Inventory data shows sparse federal services-contract activity—6 SCI records as a subcontractor across FY2022–FY2025, with 66.3 FTEs recorded in FY2024 under sub-awards and 2.7 FTEs in FY2025—reflecting that the institute's federal engagement is research-grant and OTA focused, not labor-intensive service contracting. The institute sub-awards extensively to universities including Stanford, University of Pennsylvania, Mayo Clinic, UT Health San Antonio, and UT Austin, and subcontracts on defense research through primes including University of Montana (TB vaccine research, VADP) and Travel Concepts Inc. (preclinical cancer prevention drug development). The research infrastructure includes biorepository services, flow and mass cytometry cores, transcriptomics and proteomics platforms, and nonhuman primate and transgenic mouse models, positioning the institute as a translational hub for NIH-funded mechanism-driven discovery with secondary capacity in defense innovation.
Quick answers
Is The Methodist Hospital Research Institute registered in SAM.gov?
Yes. The Methodist Hospital Research Institute's SAM.gov registration is active through December 5, 2026.
How much has The Methodist Hospital Research Institute received in federal contracts?
Federal contracts obligated $6,103,473 to The Methodist Hospital Research Institute in fiscal years 2023 through 2027.
What is The Methodist Hospital Research Institute's most recent federal award?
The Methodist Hospital Research Institute's most recent federal grant award is Mechanisms regulating tendon fibrosis and adhesion formation (F32AR085954), from National Insititue of Arthritis and Musculoskeletal and Skin Diseases (NIH), on November 29, 2026.
On GovTribe
See The Methodist Hospital Research Institute's full federal record
- Federal contract awards
- IDV awards
- Federal grant awards
- Subcontracting relationships
- Funding analysis by agency, NAICS and set-aside
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