The purpose of the computation core task is to provide computational and algorithm development support for data fusion and integration of existing cellular and animal molecular/genomic data for…

Ended Cooperative Agreement Awarded Last action

Contract number
NNX12AO52A
Awardee
Awarding agency
Obligated
$419,447

Award facts

Contract value 100% obligated
$419,447.00 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
NAICS code
Not on record
Set-aside
No set-aside
Competition
Not Competed · 0 offers Basic Research
Pricing
Other
Place of performance
Houston, TX 77030, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Funding Only Action 7 $13,754
Other Administrative Action 6 $0
Funding Only Action 5 $0
Funding Only Action 4 $123,240
Funding Only Action 3 $116,311
Funding Only Action 2 $124,311
Other Administrative Action 1 $0
Original award $41,831

Description

The purpose of the computation core task is to provide computational and algorithm development support for data fusion and integration of existing cellular and animal molecular/genomic data for heavy ION exposures with cancer phenotypes, to develop associative models of risk based on pathway activation and dimensional reduction and data transformations, to develop and validate algorithms for data fusion and integration of molecular/genomic data spawned in heavy ION experiments in the context of tissue damage, cell-cycle, cellular apoptosis and survival, cellular stressresponse, DNA damage-repair, and angiogenesis and neovascularization associated with the seeding of new metastasis, to develop biologically-motivated kinetic models of space radiation-induced carcinogenesis based on cellular growth and pathway activation, and to provide guidance on experimental criteria for reducing risk uncertainty. During the base year, the computation core will focus on development of the data repository and electronic library describing its contents, and on development of kinetic models of carcinogenesis hinged to cellular and animal data.

Quick answers

Who was awarded contract NNX12AO52A?

NNX12AO52A was awarded to The Methodist Hospital Research Institute by Shared Services Center (National Aeronautics and Space Administration) on July 31, 2012.

How much is contract NNX12AO52A worth?

The government has obligated $419,447 on NNX12AO52A.

Was contract NNX12AO52A competed?

The extent of competition for NNX12AO52A was not competed. The government received 0 offers.

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