To identify novel adjuvant candidates that can be used to augment the efficacy of human vaccines.

Active Definitive Contract Awarded Last action

Contract number
75N93019C00045
Awardee
Awarding agency
Obligated
$18,472,564

Award facts

Opportunity
Contract value 100% obligated
$18,472,563.99 Current and potential, with all options
Completion date 89% complete
Current and potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 12 offers Negotiated Proposal / Quote
Pricing
Cost No Fee
Place of performance
Missoula, MT 59812, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00026 · EO14398 vaccine ADJ discovery program (VADP) $0
Change Order P00025 $0
Funding Only Action P00024 -$0
Change Order P00023 $612,073
Other Administrative Action P00022 $0
Other Administrative Action P00021 $0
Change Order P00020 $0
Exercise an Option P00019 $2,223,085
Definitize Change Order P00018 $0
Change Order P00017 $1,599,006
Other Administrative Action P00016 $0
Change Order P00015 $2,076,197
Change Order P00014 $0
Funding Only Action P00012 $2,613,001
Other Administrative Action P00013 $0
Other Administrative Action P00011 $0
Change Order P00010 $200,000
Other Administrative Action P00009 $0
Exercise an Option P00008 $2,321,699
Other Administrative Action P00007 $0
Other Administrative Action P00006 · Vaccine ADJ discovery program (VADP) $0
Change Order P00005 · Expands the activities with research area 4 $1,199,832
Exercise an Option P00004 · Vaccine adjuvant $1,702,084
Change Order P00003 · Covid-19 $2,499,879
Other Administrative Action P00002 $0
Other Administrative Action P00001 $1,425,708
Original award $0
Show all 27

About this award

Written by GovTribe AI ·

The National Institute of Allergy and Infectious Diseases awarded a definitive contract to the University of Montana for vaccine adjuvant discovery and development on September 6, 2019, with a ceiling value of $18.5 million and an ultimate completion date of September 29, 2027.

The contract is cost-plus-no-fee and supports the Vaccine Adjuvant Discovery Program (VADP) under Executive Order 14398. Work focuses on identifying novel adjuvant candidates to augment human vaccine efficacy, with place of performance in Missoula, MT. The originating solicitation, posted January 17, 2018, called for adjuvant discovery and characterization work to advance synthetic IL-1R-based adjuvants for combination with influenza vaccines to induce rapid and sustained broadly protective immunity.

The University of Montana leads with subcontracted support from Inimmune Corp (analytical assay development, synthesis, and scale-up of lead IL-1R adjuvants); Duke University (high-throughput screening and mechanistic studies); the Icahn School of Medicine at Mount Sinai (influenza virus animal models and recombinant antigen production); the University of Chicago (M72 and 5Ag antigen production); and The Methodist Hospital Research Institute (mRNA-based TB antigen design and characterization).

Service Contract Inventory data shows contract labor scaled substantially in FY2024 (67.6 FTEs, $3.3 million invoiced) before declining in FY2025 (3.5 FTEs, $2.1 million invoiced, 7,200 contractor hours). The most recent derived hourly rate is $298.52/hr in FY2025. Subcontractors accounted for 77 percent of contractor hours in FY2025.

Subawards

Subcontractor Amount Awarded
Inimmune Corp TO IDENTIFY NOVEL ADJUVANT CANDIDATES THAT CAN BE USED TO AUGMENT THE EFFICACY OF HUMAN VACCINES. Continuation of the work being performed under PG21-61162-02… $356,336
The University Of Chicago TO IDENTIFY NOVEL ADJUVANT CANDIDATES THAT CAN BE USED TO AUGMENT THE EFFICACY OF HUMAN VACCINES. The Khader Lab at the University of Chicago is equipped to… $150,000
Inimmune Corp VACCINE ADJ DISCOVERY PROGRAM (VADP) The Adjuvant Discovery Contract proposed herein will identify, characterize, and advance novel synthetic IL-1R-based… $130,919
The Methodist Hospital Research Institute VACCINE ADJ DISCOVERY PROGRAM (VADP) HMRI (Dr. Dan Kiss sub-PI) is responsible for the design, production, characterization and QA/QC of mRNA based TB… $356,698

Quick answers

Who was awarded contract 75N93019C00045?

75N93019C00045 was awarded to University Of Montana by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on September 6, 2019.

How much is contract 75N93019C00045 worth?

The government has obligated $18,472,564 on 75N93019C00045.

Was contract 75N93019C00045 competed?

The extent of competition for 75N93019C00045 was full and open competition. The government received 12 offers.

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