Roke Biotechnologies LLC

Durham, NC

UEI
VZ4VTRBGKQB3
CAGE
9A9L8
Primary NAICS
541714 Research and Development in Biotechnology (except Nanobiotechnology)
SAM.gov registration
Active through

Company facts

Self-certified in SAM.gov
  • For Profit Organization
  • Subchapter S Corporation
Entity structure
Partnership or Limited Liability Partnership
SAM.gov registration date
Physical address
701 W Main St #410, Durham, NC 27701, USA
Website
rokebio.com
Industry
  1. Health Care
  2. Pharmaceuticals, Biotechnology & Life Sciences
  3. Pharmaceuticals
SIC code
28 Chemical & Allied Products
Profiles

Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .

Grant awards

Grant subawards

Prime recipient Prime award Amount Awarded
Bioindustrial Manufacturing And Design Ecosystem Low-Cost Nanobody-Based Growth Factor Replacements FA86502125028 $153,380
Georgia TECH Research Corp The goal of this project is to develop a framework for facile, composable reuse of cell-free functionalities via easily combined modules. Key aims for this… 2452482 $285,430

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About the company

Roke Biotechnologies LLC, a Durham, North Carolina–based limited liability company and biomanufacturing technology developer, operates as a recipient of federal research grants and as a subrecipient on NSF-funded projects, with minimal federal prime contract exposure. The vendor's footprint consists of three awards across two federal agencies — predominantly NSF work — totaling $744 thousand in combined obligated dollars over the past eighteen months.

The National Science Foundation is the dominant funder, accounting for two of three awards. Roke serves as prime recipient on an NSF Technology, Innovation, and Partnerships (STTR Phase I) grant awarded July 1, 2026, for $305 thousand, with performance running through June 30, 2027. The project develops a low-cost manufacturing platform for agricultural peptides using semi-continuous bacterial fermentation integrated with simplified purification methods, addressing three technical challenges: maintaining stable protein production over extended operation without genetic drift, integrating multiple processing steps into a coordinated continuous system, and protecting sensitive peptide products from degradation during purification. Success criteria include target expression levels, purification yields above ninety percent, and continuous operation for seventy-two hours or longer without performance decline. Roke planned sub-awards under this grant. As a subrecipient, Roke receives funding from two NSF-funded prime recipients: Georgia Tech Research Corporation (sub-award dated December 4, 2025) for cell-free protein expression module development and framework integration, and Bioindustrial Manufacturing and Design Ecosystem (sub-award dated April 6, 2026) for low-cost nanobody-based growth factor replacement research. A single award from the Department of the Army Materiel Command TACOM Life Cycle Management Command rounds out the agency set. Activity shows two awards in 2026 against one in 2025. One award reaches ultimate completion within the next twenty-four months, triggering recompete exposure. Roke's capability footprint centers on scalable biomanufacturing, protein expression systems, and fermentation process engineering for agricultural and biotechnology applications, with federal research funding routed through NSF small-business innovation programs and cooperative research vehicles rather than defense or civilian agency procurement.

Quick answers

Is Roke Biotechnologies LLC registered in SAM.gov?

Yes. Roke Biotechnologies LLC's SAM.gov registration is active through October 6, 2027.

What is Roke Biotechnologies LLC's most recent federal award?

Roke Biotechnologies LLC's most recent federal grant award is Sttr phase i: low-cost production of agricultural peptides using semi-continuous fermentation (2538032), from National Science Foundation, on July 1, 2026.

On GovTribe

See Roke Biotechnologies LLC's full federal record

  • Federal grant awards
  • Funding analysis by agency, NAICS and set-aside
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