Epigenome Technologies, Inc.

Epigenome Technologies, Inc. is a for-profit company that provides specialized laboratory services and cutting-edge biotechnology research for the federal government, particularly in the fields of epigenetics, single-cell biology, and multi-omics analysis. The company's core offering is its proprietary "Paired-Tag" technology, which enables joint profiling of gene expression and epigenetic modifications like histone marks at single-cell resolution.

Through federal contract awards from agencies like the National Institutes of Health (NIH) and National Institute on Aging (NIA), Epigenome Technologies has provided laboratory services for paired-tag sample library preparation. These firm-fixed-price purchase orders engage the company to perform specialized sample prep work, supporting research efforts in areas such as Alzheimer's disease and cancer biology. No set-asides have been utilized for these contract awards.

Epigenome Technologies has also received several multi-year project grants from NIH institutes like NIGMS, NIA, and NIMH. These grants, ranging from around $1 million to $1.4 million, fund the development and optimization of the company's paired-tag technology for high-throughput single-cell co-assays of transcriptomes and epigenetic marks. Key aims include establishing automated protocols, building laboratory informatics systems, adapting the technology to long-read sequencing, and applying it to study brain disorders like Alzheimer's disease. The grants support innovative multi-omic analyses that can elucidate cell type-specific gene regulatory programs and provide functional annotation of disease-associated genetic variants.

A small woman owned company specialized in single cell multi-omics sequencing applied to cancer research.