Acpharis
Holliston, MA Doing business as Acpharis
- UEI
- E4Z3M7L7NHT3
- CAGE
- 5DK90
- SAM.gov registration
- Active through
Company facts
- Self-certified in SAM.gov
- Entity structure
- Corporate Entity (Not Tax Exempt)
- NAICS codes registered in SAM.gov
- SAM.gov registration date
- Physical address
- 160 N Mill St, Holliston, MA 01746, USA
- Website
- acpharis.com
- Founded
- 2008
- Employees
- 1-10
- Estimated annual revenue
- $0-$1M
- Industry
-
- Materials
- Chemicals
- SIC code
- 28 Chemical & Allied Products
- Profiles
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Recent federal awards
| Award | Agency | Obligated | Awarded |
|---|---|---|---|
| Software for increased accuracy prediction of antibody-antigen complexes - antibodies are important drugs to treat… | National Institute of General Medical Sciences | $202,467 | |
| Algorithm and software for predicting the structure and degrading efficiency of protacs - the use of proteolysis… | National Institute of General Medical Sciences | $202,274 | |
| Deep learning augmented protein mapping software to screen large compound libraries - fragment based drug discovery… | National Institute of General Medical Sciences | $346,012 | |
| Software for antibody epitope prediction | National Institute of General Medical Sciences | $149,999 | |
| Development of structure based potential for protein mapping | National Institute of General Medical Sciences | $204,249 |
About Acpharis
Acpharis is a for-profit corporate entity based in Holliston, Massachusetts, specializing in computational biology and software development for advanced scientific research. Registered in SAM.gov since 2009, the company focuses on developing sophisticated computational tools for protein structure prediction, drug discovery, and molecular modeling. Their core competency involves creating advanced software solutions that leverage machine learning, physics-based sampling, and innovative algorithmic approaches to address complex biological research challenges.
The company has secured multiple project grants from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program, demonstrating expertise in developing cutting-edge computational tools for life sciences. These grants have supported the development of software for predicting antibody-antigen complex structures, creating programs for modeling proteolysis targeting chimeras (PROTACs), and developing protein mapping software for screening compound libraries. Specifically, Acpharis has developed GPU-accelerated versions of protein docking programs like PIPER, created custom versions of machine learning tools like AlphaFold2, and designed software packages that can screen large virtual compound libraries for potential drug discovery hits. Their work integrates advanced machine learning techniques with physics-based computational methods, enabling more accurate and efficient molecular structure predictions and potentially accelerating research in areas such as cancer treatment, infectious diseases, and drug development.
Quick answers
What is Acpharis's UEI?
Acpharis's Unique Entity ID (UEI) in SAM.gov is E4Z3M7L7NHT3.
What is Acpharis's CAGE code?
Acpharis's CAGE code is 5DK90.
What is Acpharis's primary NAICS code?
Acpharis's primary NAICS code is 541714 (Research and Development in Biotechnology (except Nanobiotechnology)).
Where is Acpharis located?
Acpharis's physical address in SAM.gov is 160 N Mill St, Holliston, MA 01746, USA.
Is Acpharis registered in SAM.gov?
Yes. Acpharis's SAM.gov registration is active through September 1, 2027.
What is Acpharis's most recent federal award?
Acpharis's most recent federal grant award is Software for increased accuracy prediction of antibody-antigen complexes - antibodies are important drugs to treat… (R43GM161151), from National Institute of General Medical Sciences, on September 1, 2025.
On GovTribe
See Acpharis's full federal record
- Federal grant awards
- Funding analysis by agency, NAICS and set-aside
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