Pumpkinseed Technologies Inc.

Pumpkinseed Technologies Inc. is a for-profit biotechnology research and development company located in Palo Alto, California, specializing in advanced optical and machine learning technologies for proteomics and cellular analysis. Registered in SAM.gov since June 8, 2022, the company focuses on developing cutting-edge technologies that enable high-throughput protein sequencing, characterization, and monitoring at the cellular level. The company's work primarily centers on innovative approaches to understanding protein structures, interactions, and modifications using advanced optical techniques and artificial intelligence algorithms.

Through its federal grant awards, Pumpkinseed Technologies Inc. has secured multiple Small Business Innovation Research (SBIR) grants from agencies including the National Science Foundation, National Cancer Institute, and National Institute of General Medical Sciences. The company's primary research focuses on developing sophisticated technologies like Cell-MAPP for monitoring T cell states, Vibrational Spectroscopy with Metasurface Optics (VISMO) for protein post-translational modification identification, and a high-throughput de-novo peptide sequencing technology. These projects aim to revolutionize proteomics, cancer research, immunotherapy, and drug development by providing unprecedented insights into protein structure, cellular dynamics, and immune responses. The grants, ranging from $275,000 to $1,249,115, support the development of label-free, high-resolution screening platforms that can simultaneously analyze millions of protein samples, with potential applications in personalized medicine, vaccine design, cancer immunotherapy, and understanding complex cellular processes.