Cooperative Agreements to Support State-Based Safe Motherhood and Infant Health Initiative Programs

Active

Assistance listing
93.946
Agency
Grant awards
582 $710,898,721 in federal obligations

Program facts

Also known as
Safe Motherhood and Infant Health (Reproductive Health)
Assistance types
  • Cooperative Agreement
  • Project Grant
  • Block Grant
Treasury account
  • 75-0948-0-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Centers for Disease Control and Prevention announced the availability of funding through Cooperative Agreements to support state-based Safe Motherhood and Infant Health Initiative Programs (CFDA 93.946) most recently on September 30, 2024. The program funds maternal mortality review committees, perinatal quality collaboratives, and pregnancy-associated mortality surveillance—multidisciplinary processes that identify and characterize pregnancy-related deaths, abstract clinical and non-clinical data into standardized systems, conduct informant interviews, and develop prevention recommendations to reduce maternal and infant mortality disparities.

Recent grant activity is robust. The program has disbursed 582 awards since 2002, with 190 awards in the past five years alone (2020–2024), averaging 38 awards annually. The most recent award batch on September 30, 2024, funded 57 recipients including maternal mortality review projects across Tennessee ($3.57 million), Minnesota ($4.95 million), Missouri ($3.42 million), New Jersey ($4.04 million), and New York ($3.1 million), alongside perinatal quality collaboratives and sudden infant death surveillance registries. Combined federal obligation across the portfolio is $710.9 million. Cooperative Agreements dominate the mix at 81 percent of awards (472), with Project Grants and Block Grants comprising 16 and 3 percent respectively.

Funding is concentrated within CDC across multiple sub-components. The portfolio block reports eight distinct funding federal agencies, all listed as "Department of Health and Human Services Centers for Disease Control and Prevention"—reflecting internal CDC division funding. The top funding components by obligation are maternal mortality review and quality collaborative initiatives ($379.8 million from the largest component group), followed by surveillance and SUID/SDY registry programs ($173.6 million and $130.6 million respectively).

Award magnitude varies by initiative. Maternal mortality review cooperative agreements range from $265 thousand (Southern California statewide collaborative) to $4.95 million (Minnesota), with most five-year awards in the $1.5 to $3 million range. SUID case registry projects typically fall between $450 thousand and $2.8 million. Cooperative agreement periods run one to five years from initial award, with the option for non-competitive continuation contingent on satisfactory progress.

Recent grant opportunities remain active. CDC-RFA-DP-27-0043 (Statewide Perinatal Quality Collaboratives) was posted July 27, 2026, and funds state PQCs and a national coordinating center to improve perinatal outcomes through data-driven quality improvement. CDC-RFA-DP-24-0053 (Enhancing Reviews and Surveillance to Eliminate Maternal Mortality), posted August 3, 2023, with a May 23, 2024 due date (now closed), supported maternal mortality review committees identifying pregnancy-related deaths and reducing disparities. Both solicit multi-component applications from state, tribal, and local health agencies as well as nonprofits and academic institutions. The program has sustained funding cycles approximately 12–24 months apart. Check Grants.gov for current NOFO details and requirements.

Objective and description

Objective

To promote optimal and equitable health in women and infants through public health surveillance, research, leadership, and partnership to move science to practice. In carrying out this mission, the Division of Reproductive Health: 1) Enhances the ab

Description

To promote optimal and equitable health in women and infants through public health surveillance, research, leadership, and partnership to move science to practice.

Eligibility

Applicant eligibility

Reference posted NOFOs available on Grants.gov

Beneficiary eligibility

Official State and Territorial public health agencies. City of New York public health agency and District of Columbia. Applications may be submitted by public and private nonprofit and for-profit organizations and by governments and their agencies; that is, universities, colleges, research institutions, hospitals, other public and private nonprofit and for-profit organizations, State and local governments or their bona fide agents, including the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Mariana Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau, federally recognized Indian tribal governments, Indian tribes, or Indian tribal organizations, and small, minority, women-owned businesses.

Uses of assistance

PRAMS: The Pregnancy Risk Assessment Monitoring System, is a surveillance project of the Centers for Disease Control and Prevention (CDC) and state health departments. PRAMS collects state-specific, population-based data on maternal attitudes and experiences before, during, and shortly after pregnancy. SID/SUID (Sudden infant Death/Sudden Unexplained Infant Death): The SUID Case Registry aims to generate public health surveillance information about SUID at the national, state, and local levels that is more detailed than what is currently available. Instead of creating an entirely new system, the SUID Case Registry enhances the National Center for Child Death Review program and their Case Reporting System. Validation of Prenatal Substance Use Screening Tools: The purpose of this research is to validate and compare the performance of the most promising substance abuse screening tools that are already available in the literature (for example, the 4Ps-plus, the 5Ps, the Substance Use Risk Profile - Pregnancy Scale (SURP-P), the CRAFFT, the NIDA Quick Screen) and can be used among pregnant women seeking medical services (e.g. antenatal or delivery care) in clinical settings in the United States. Medicaid Expansion and Reproductive Health Care for Women: The intent is to study the use of medical services and health outcomes among low-income women of reproductive age (15-44 years), before and after expansion of Medicaid eligibility. This research will require linkage of state Medicaid data with other key maternal and child health datasets including, but not limited to, birth certificates, death certificates, and hospital discharge data. Perinatal Quality Collaboratives: will support states to enhance the capabilities of state-based perinatal quality collaboratives to improve the quality of perinatal care in their states, including but not limited to: reducing early elective deliveries, increasing use and documentation of use of antenatal steroids, increasing breastfeeding rates, and reducing central line-associated blood stream infections in neonates. Maternal and Child Health Capacity Building:The program promotes and improves the health and well-being of women, children, and families by building capacity at state, local, and tribal levels and to use and apply sound epidemiologic research and scientific information to maternal and child health programs and policies through collaborations with partners. Special Interest Project (SIP)/Progestin contraception and HIV risk: Clinical and laboratory follow-up of a cohort of HIV-infected and uninfected women: The purpose of this SIP is to establish a cohort of HIV-infected and HIV-uninfected women on different types of progestin-containing contraception to assess differences in women's continuation with a given method and the effects of long-term progestin use on markers of HIV risk and efficacy of ART. Also the project will support laboratory studies to analyze the effects of progestin on HIV shedding, inflammatory/immune markers in the genital tract, and the interaction of progestin with antiretroviral therapy on contraceptive and ART efficacy. Objectives in the topic area of Family Planning and HIV Prevention intend to Increase the proportion of pregnancies that are intended; increase the proportion of sexually experienced persons who received reproductive health services; reduce pregnancy rates among adolescent females; and reduce the rate of HIV transmission among adolescents and adults. Teen Pregnancy Prevention: The program is supporting public and private entities to fund medically accurate and age appropriate evidence-based or innovative program models to reduce teen pregnancy. The purpose of the program is to reduce teen pregnancy by working directly with publicly funded clinics to increase access to and use of reproductive health services among vulnerable youth. Activities include building the capacity of staff and clinical providers, establishing partnerships with youth-serving systems, and developing communication efforts. The primary target population is 15- to 19-year-olds, the age group among whom the majority of teen births occur; however, since the Society of Adolescent Health and Medicine and the United Nations Family Planning Association define adolescents as 15-24, the target age group may be expanded. Development and Testing of a Clinic-Based Intervention to Increase Dual Protection against Unintended Pregnancy and STDs among High Risk Female Teens: The purpose of this funding opportunity is to develop and evaluate a clinic-based intervention addressing access to, motivation for, and adherence to dual protection strategies that concurrently protect against unintended pregnancies and sexually transmitted diseases (STDs), including human immunodeficiency virus (HIV) among high risk 15-19 year old females.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity Announcements (NOFOs). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific and technical merit by objective or peer review, availability of funds, and relevance of program priorities and the priorities of CDC.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Deadlines

Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.

Time to approval or disapproval

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Renewals

Cooperative agreement period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.

Grant opportunities

Opportunity Status Posted Applications due
Statewide Perinatal Quality Collaboratives: Improving Perinatal Care and Outcomes CDC-RFA-DP-27-0043 Forecasted —
Enhancing Reviews and Surveillance to Eliminate Maternal Mortality CDC-RFA-DP-24-0053 Closed
The Sudden Unexpected Infant Death (SUID) and Sudden Death in the Young (SDY) Case Registry CDC-RFA-DP-23-0006 Closed
Preventing Maternal Mortality: Supporting Maternal Mortality Review Committees CDC-RFA-DP-23-0066 Closed
Preventing Maternal Mortality: Supporting Maternal Mortality Review Committees CDC-RFA-DP22-2211 Closed
Statewide Perinatal Quality Collaboratives CDC-RFA-DP22-2207 Closed
Pregnancy Risk Assessment Monitoring System (PRAMS) RFA-DP-21-001 Closed
State-based Perinatal Quality Collaboratives CDC-RFA-DP17-1702 Closed
Paul Coverdell National Acute Stroke Prevention Program CDC-RFA-DP15-151403CONT17 Closed
Pregnancy Risk Assessment Monitoring System (PRAMS) RFA-DP-16-001 Closed
Sudden Unexpected Infant Death (SUID) Case Registry: Building Capacity (Module A) and Implementation (Module B) CDC-RFA-DP15-1506 Closed
Working with Publicly Funded Health Centers to Reduce Teen Pregnancy among Youth from Vulnerable Populations CDC-RFA-DP15-1508 Closed
Maternal and Child Health Epidemiology: National and State Coalition Capacity Building to Improve Outcomes CDC-RFA-DP15-1507 Closed
Paul Coverdell National Acute Stroke Prevention CDC-RFA-DP15-1514 Closed
Sudden Death in the Young (SDY) Registry CDC-RFA-DP14-140302CONT15 Closed
Effectiveness of Teen Pregnancy Prevention Programs Designed Specifically for Young Males RFA-DP-15-007 Closed
Cost-Benefit of Incentive-based Smoking Cessation for Pregnant Women RFA-DP-13-003 Closed
Development and Testing of a Clinic-Based Intervention to Increase Dual Protection against Unintended Pregnancy and STDs among High Risk Female Teens RFA-DP-12-001 Closed
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Grant awards

Award Recipient Federal obligations Awarded
Enhancing reviews and surveillance to eliminate maternal mortality - 2024 NU58DP007949 Ohio Department Of Children And Youth $2,975,000
Enhancing reviews and surveillance to eliminate maternal mortality - 2024 NU58DP007948 California Department Of Public Health $1,860,000
Statewide perinatal quality collaboratives - 2022 NU58DP007947 University Of Texas Health Science Center At Houston $1,590,276
Wisconsin supporting maternal mortality review NU58DP007830 State Of Wisconsin Department Of Health Services $2,525,000
This funding will support missouri's pregnancy-associated mortality review (pamr) program by facilitating timely… NU58DP007829 Missouri Department Of Health & Senior Services $3,420,000
Enhancing reviews and surveillance to eliminate maternal mortality NU58DP007828 Minnesota Department Of Health $4,950,000
Maternal mortality review committee financial support to improve data quality and timeliness. NU58DP007827 Oklahoma State Department Of Health $1,980,000
Connecticut maternal mortality review program NU58DP007825 Department Of Public Health Connecticut $2,590,000
Iowa's enhancing reviews and surveillance to eliminate maternal mortality program NU58DP007824 Iowa Department Of Public Health $3,010,000
Enhancing review and surveillance to eliminate maternal mortality NU58DP007823 Indiana Department Of Health $2,280,000

Latest 10 of 582 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 177 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $24,830,256
FY2025 $74,022,049
FY2024 $158,786,562
FY2023 $71,318,498
FY2022 $51,344,574
FY2021 $13,806,990
FY2020 $29,467,577
FY2019 $37,763,943
FY2018 $16,141,287
FY2017 $18,983,776
FY2016 $17,520,570
FY2015 $14,343,373
FY2014 $11,788,753
FY2013 $11,943,902
FY2012 $12,473,513
FY2011 $12,862,001
FY2010 $11,367,439
FY2009 $16,323,235
FY2008 $5,130,746
FY2007 $12,753,255
FY2006 -$4,210,872
FY2005 $1,243,775
FY2004 $1,625,320
FY2003 $712,320
FY2002 -$43,725
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Quick answers

What is Assistance Listing 93.946?

Assistance Listing 93.946 is Cooperative Agreements to Support State-Based Safe Motherhood and Infant Health Initiative Programs, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Cooperative Agreements to Support State-Based Safe Motherhood and Infant Health Initiative Programs?

Its CFDA number is 93.946: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.946 awarded?

582 grant awards under 93.946 have obligated $710,898,721 in federal funds to 177 recipients.

Who receives the most funding from 93.946?

The recipients obligated the most under Cooperative Agreements to Support State-Based Safe Motherhood and Infant Health Initiative Programs are National Indian Health Board ($31,247,030), National Association Of Chronic Disease Directors, Inc. ($23,057,800) and Louisiana Department Of Health ($16,080,007).

How much did 93.946 obligate in fiscal year 2025?

Grants under 93.946 obligated $74,022,049 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.946?

1 listed opportunity under 93.946 is open or forecasted. The latest, Statewide Perinatal Quality Collaboratives: Improving Perinatal Care and Outcomes, was posted on July 27, 2026.

On GovTribe

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