Leading Edge Acceleration Projects (LEAP) in Health Information Technology

Active

Assistance listing
93.345
Agency
Grant awards
18 $23,593,246 in federal obligations

Program facts

Also known as
LEAP
Assistance type
  • Cooperative Agreement
Treasury account
  • 75-0130-0-1-551
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Health and Human Services Office of the National Coordinator for Health Information Technology (ONC) funds cooperative agreements under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology program (CFDA 93.345) to develop and test interoperable health IT solutions addressing barriers to nationwide data exchange and clinical knowledge integration, with grant opportunities currently open and due July 16, 2026.

The program funds development and pilot testing of health IT capabilities aligned with 21st Century Cures Act interoperability mandates. Recent awards demonstrate concrete focus: demonstrating FHIR-based subscriptions capability for real-time clinical decision support (NORC at the University of Chicago partnership, awarded September 2025, $1.998 million); testing innovative technical approaches to increase adoption of Individual Access Services under the Trusted Exchange Framework and Common Agreement (HIMSS collaboration, awarded September 2025, $1.999 million); adapting open-source FHIR applications for behavioral health care planning and information exchange (awarded September 2024, $1.998 million); and developing AI-informed approaches to nursing data processing for early warning systems (awarded September 2024, $1.997 million). Additional recent work has addressed advance care planning document aggregation via FHIR interoperability, FHIR data quality improvement frameworks, patient-generated health data integration for equity-enhanced care, and cross-sector care coordination linking healthcare with housing and social services.

ONC is the sole funder. All 18 awards in the portfolio are cooperative agreements totaling $23.6 million federal dollars obligated. Awards have consistently dispersed at roughly two per year from 2021 through 2025, with individual awards typically ranging from approximately $1.97 million to $2 million over multiyear periods.

Eligible applicants include public and private nonprofit institutions (universities, colleges, faith-based and community-based organizations), units of state and local government, federally recognized Indian/Native American Tribal Governments, and in limited capacity, for-profit organizations as sub-recipients within consortia only. The most recent open solicitation (NAP-AX-26-001, due July 16, 2026) is seeking three cooperative agreements for two-year projects addressing three priority areas: agentic AI integration with health IT systems, and continuation of prior emphasis on FHIR-based subscriptions and TEFCA infrastructure innovation. A prior solicitation (NAP-AX-22-001, originally extended through September 30, 2027, with most recent update noting application period extended to April 25, 2025) remains available for the same two focus areas. Renewals are available for awardees demonstrating measurable progress toward project goals.

Objective and description

Objective

The goal of the LEAP in Health IT funding opportunity is to address well-documented and fast emerging challenges inhibiting the development, use, or advancement of well-designed, interoperable health IT, which are scalable across the healthcare indus

Description

It is critical for the health IT field to be able to innovate and leverage the latest technological advancements and breakthroughs to optimize real-time solutions, especially in areas where health IT has potential to improve the health and healthcare for individuals and populations. The descriptions provided for the two areas of interest, Area 1 and Area 2, include ways applicants may approach developing a project. The areas of interest have been assigned numbers for ease of reference, not for prioritization. While there are many challenges associated with the use of health IT, ASTP identified these two areas of interest as 2025 priority areas: • Area 1: Demonstrate readiness of FHIR®-based Subscriptions capability as a foundational health IT capability for improved interactivity with third-party applications. • Area 2: Identify and test innovative technical approaches that would inform future changes to the TEFCA infrastructure to increase adoption of IAS.

Eligibility

Applicant eligibility

Public or non-profit private institutions, such as a university, college, or a faith-based or community-based organization; units of local or state government, eligible agencies of the federal government, Indian/Native American Tribal Governments (federally recognized, other than federally recognized, and tribally designated organizations).

Uses of assistance

For Objective 1: The goal of this focus area is for the awardee to develop a prototype and propose enhancements to existing technical specifications that would make it possible for an independent entity to securely access data on various populations of patients from a FHIR-based API. For Objective 2: The goal of this focus area is to advance clinical knowledge into the health care setting via innovative health IT tools and solutions.

Length and time phasing of assistance

Assistance will be available during the period of performance of the award (September 2018-2023), and 90 days after the close of the period of performance for reconciliation.

How to apply

Criteria for selecting proposals

Proposals will be reviewed by a review panel comprised of no less than one (1) federal employee and subject matter experts (non-federal employees). Each proposal will receive a score based on strength and merit of their proposals based on the merit review criteria of Understanding of Project Purpose, Approach and Activities, Applicant Capabilities , and Budget, Level of Effort, and Justification. A detailed list of merit review criteria in these areas are detailed in the funding opportunity announcement.

Award procedure

The final award decision will be made by the National Coordinator for Health Information Technology taking into consideration several factors such as the results of the merit review process, results of the pre-award risk assessment, compliance with programmatic and grants management requirements; the reasonableness of the estimated costs, available funding, geographical dispersion, program priorities; and the likelihood that the proposed project will result in the benefits expected. All applicants will receive a summary of the objective review panel's assessment of the application's strengths, weaknesses, and score. The recipients Authorized Representatives will receive the notice of award electronically from ONC. The Recipient accepts the award by drawing down funds. By accepting an ONC award, the recipient assumes legal, financial, administrative, and programmatic responsibility for administering the award in accordance with the terms and conditions of the award, as well as applicable laws, rules, regulations, and Executive Orders governing HHS assistance awards, all of which are to be incorporated into the award by reference. Failure to comply with these requirements may result in suspension or termination of the awards and/or ONC's recovery of award funds.

Renewals

Renewals may be available if the applicant is able to successfully show progress towards achieving specified goals.

Grant opportunities

Opportunity Status Posted Applications due
Leading Edge Acceleration Projects (LEAP) in Health Information Technology NAP-AX-26-001 Closed
Leading Edge Acceleration Projects (LEAP) in Health Information Technology NAP-AX-22-001 Open
Leading Edge Acceleration Projects for Health IT (LEAP) ONC-NAP-AX-22-001 Past —
Leading Edge Acceleration Projects (LEAP) in Health Information Technology NAP-AX-18-003 Closed

Grant awards

Award Recipient Federal obligations Awarded
Leading edge acceleration projects (leap) in health information technology - the healthcare information and… 90AX0045 Healthcare Information And Management Systems Society $1,999,536
Powering proactive care: fhir subscriptions as the foundation for time-sensitive patient-centered decision support… 90AX0044 National Opinion Research Center $1,998,454
Scalable, shareable, and computable clinical knowledge for AI-based processing of hospital-based nursing data 90AX0042 The Trustees Of Columbia University In The City Of New York $1,997,806
Behavioral health ecareplan collaborative project 90AX0041 Oregon Health & Science University $1,998,660
Cumulusq: an open source platform for improving fhir data quality across the ecosystem - the cumulusq project is… 90AX0040 The Children's Hospital Corporation $1,999,954
Advanced fhir capabilities for advance care planning use cases to improve patient care - project title: advanced fhir… 90AX0039 Healthelink, Inc. $2,000,000
Aligning housing and healthcare - alliancechicago, a health resources and services administration funded health… 90AX0037 Alliancechicago $2,000,000
Equity engines: leveraging hujan-in-the-loop patient-generated health data with automation to optimize equity… 90AX0036 Medstar Health Research Institute Inc. $2,000,000
Semantic interoperability for electronic health data using the layered schemas architecture 90AX0034 Dartnet Institute $999,990
Fhir-enabled social and health information platform (fhired-ship): integrating a closed-loop social services referral… 90AX0033 University Of Texas At Austin $963,421

Latest 10 of 18 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 13 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 -$34,697
FY2025 $3,997,990
FY2024 $3,995,214
FY2023 $3,954,365
FY2022 $3,933,908
FY2021 $1,998,108
FY2020 $3,449,348
FY2019 $300,000
FY2018 $1,999,010

Quick answers

What is Assistance Listing 93.345?

Assistance Listing 93.345 is Leading Edge Acceleration Projects (LEAP) in Health Information Technology, a federal grant program run by Immediate Office of the Secretary (Department of Health and Human Services).

What is the CFDA number for Leading Edge Acceleration Projects (LEAP) in Health Information Technology?

Its CFDA number is 93.345: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.345 awarded?

18 grant awards under 93.345 have obligated $23,593,246 in federal funds to 13 recipients.

Who receives the most funding from 93.345?

The recipients obligated the most under Leading Edge Acceleration Projects (LEAP) in Health Information Technology are The Children's Hospital Corporation ($4,399,810), Medstar Health Research Institute Inc. ($3,997,199) and Alliancechicago ($2,000,000).

How much did 93.345 obligate in fiscal year 2025?

Grants under 93.345 obligated $3,997,990 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.345?

1 listed opportunity under 93.345 is open or forecasted. The latest, Leading Edge Acceleration Projects (LEAP) in Health Information Technology, was posted on June 16, 2026.

On GovTribe

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