Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects

Active

Assistance listing
93.185
Agency
Grant awards
251 $3,675,701,311 in federal obligations

Program facts

Assistance types
  • Cooperative Agreement
  • Block Grant
  • Project Grant
Treasury account
  • 75-0943-0-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Centers for Disease Control and Prevention (CDC) funds research, demonstration projects, and public information and education activities on vaccine-preventable diseases and immunization programs under Assistance Listing 93.185, with the most recent award (Cooperative Agreement NH23IP922710 to Texas) disbursed July 1, 2025.

The program has awarded 251 grants totaling $3.68 billion in combined federal obligation since its inception in 2002, with activity concentrated in recent years: seven awards in 2024, six in 2023, three in 2021, and one in 2025. The funding landscape has remained relatively stable, with awards typically covering one to five-year periods of performance; initial funding covers the first 12 months, with non-competitive continuation available for up to five years subject to satisfactory recipient progress and fund availability.

Funded activities span vaccine delivery infrastructure, disease surveillance and outbreak response, vaccine effectiveness evaluation, vaccine confidence and demand campaigns, epidemiologic training and capacity building, and health equity improvements. Representative projects include strengthening state immunization programs to increase vaccination access and equity (Texas, $57.5 million); evaluating respiratory virus vaccine effectiveness in large diverse healthcare systems (multiple sites); developing outbreak analytics and disease modeling tools for public health response (academic centers, $27–44 million each); promoting vaccine confidence through trusted messengers and community health workers; and supporting global polio eradication modeling and immunization program capacity in low- and middle-income countries.

Funding is overwhelmingly concentrated in CDC, which obligated $3.79 billion across 249 awards (99 percent of award count). The assistance-type mix is predominantly Cooperative Agreements (172 awards, 69 percent) with smaller shares of Project Grants (53 awards, 21 percent) and Block Grants (26 awards, 10 percent). Typical award sizes range from $800 thousand to $3 million annually for state immunization programs and smaller research projects, with larger awards to national research networks and capacity-building organizations reaching $5–44 million over multi-year periods.

Multiple NOFOs are currently open or recently posted. RFA-IP-27-026 (posted July 28, 2026) seeks five cooperative agreement awards up to $1.8 million annually per site for the US Influenza Vaccine Effectiveness Network, conducting vaccine effectiveness surveillance and household transmission research; CDC-RFA-IP-26-0102 (posted August 1, 2025, due June 29, 2026) seeks to establish an influenza modeling and forecasting network to inform CDC's situational awareness and control strategies; and RFA-IP-25-111 (posted August 6, 2024, due February 6, 2025) supports rapid-cycle surveys of healthcare providers and the public on immunization issues. CDC-RFA-JG-27-0077, posted August 31, 2026, targets innovative disease modeling approaches to inform global polio eradication strategy.

Objective and description

Objective

To assist states, political subdivisions of states, and other public and private nonprofit entities to conduct research, demonstration projects, and provide public information on vaccine-preventable diseases and conditions.

Description

To assist states, political subdivisions of states, and other public and private nonprofit entities to conduct research, demonstration projects, and provide public information on vaccine-preventable diseases and conditions.

Eligibility

Applicant eligibility

Under Section 317(k) of the Public Health Service Act: States, political subdivision of states, and other public and private nonprofit entities.

Beneficiary eligibility

Under Section 317(k) of the Public Health Service Act: States, political subdivisions of states, and other public and private nonprofit entities.

Uses of assistance

Project funds may be used for costs associated with organizing and conducting these projects, and in certain circumstances, for purchasing vaccine. Requests for direct assistance (i.e., "in lieu of cash") for personnel, vaccines, and other forms of direct assistance will be considered. Funds may not be used to supplant existing immunization program activities.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity Announcements (NOFOs). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific and technical merit by objective or peer review, availability of funds, and relevance of program priorities and the priorities of CDC.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Deadlines

Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.

Renewals

Cooperative agreement period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.

Grant opportunities

Opportunity Status Posted Applications due
Informing global polio eradication efforts through innovative modeling approaches CDC-RFA-JG-27-0077 Forecasted —
Improving Protection against Influenza and Other Respiratory Pathogens: the US Flu VE Network RFA-IP-27-026 Forecasted —
Influenza Modeling and Forecasting CDC-RFA-IP-26-0102 Closed
Rapid-Cycle Survey Collaborative for Provider and Public Input on Immunization Issues RFA-IP-25-111 Closed
Partnerships to Enhance Immunization Information Systems (IIS) CDC-RFA-IP-24-0079 Closed
Understanding Adult Immunization Quality Improvement Approaches Among Adult HCP and Health Departments RFA-IP-23-002 Closed
Programmatic Interventions to Increase Uptake of Influenza and COVID-19 Vaccination Among Students Attending Institutions of Higher Education RFA-IP-23-003 Closed
Approach to Adult Vaccine Counseling RFA-IP-23-005 Closed
Developing, Implementing, and Evaluating Protocols to Increase Routine Adult Immunization Coverage Among Persons Who are Incarcerated RFA-IP-23-004 Closed
Collaborative Surveys to Provide Inputs into Vaccine-Related Economic Evaluations RFA-IP-23-007 Closed
Developing a Public Health Tool to Predict the Virality of Vaccine Misinformation Narratives RFA-IP-23-006 Closed
Advancing the capacity of immunization program managers through a national coordinating organization CDC-RFA-IP-23-0004 Closed
Informing global polio eradication efforts through innovative modeling approaches CDC-RFA-GH22-2272 Closed
Tracking the burden, distribution, and impact of Post COVID-19 conditions in diverse populations for children, adolescents, and adults (Track PCC) CDC-RFA-IP22-2203 Closed
Tracking the Burden, Distribution, and Impact of Post-COVID-19 Conditions in Diverse Populations of Children, Adolescents and Adults (Track PCC) RFA-IP-22-002 Past —
US Platform to Measure Effectiveness of Seasonal Influenza, COVID-19 and other Respiratory Virus Vaccines for the Prevention of Acute Illness in Ambulatory Settings RFA-IP-22-004 Closed
Partnering with National Organizations to Support Community-Based Organizations to Increase Vaccination Coverage Across Different Racial and Ethnic Adult Populations Currently Experiencing Disparities CDC-RFA-IP21-2108 Closed
Partnering with Professional and Medical Associations to Increase Vaccination Coverage Across Different Racial and Ethnic Adult Populations Experiencing Disparities CDC-RFA-IP21-2107 Closed
Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling CDC-RFA-GH21-2101 Closed
Partnering with National Organizations to Increase Vaccination Coverage Across Different Racial and Ethnic Adult Populations Currently Experiencing Disparities CDC-RFA-IP21-2106 Closed
Annual Estimates of Influenza Vaccine Effectiveness for Preventing Medically Attended Laboratory-Confirmed Influenza in the United States RFA-IP-21-005 Past —
US Enhanced Surveillance Network to Assess Burden, Natural History, and Effectiveness of Vaccines to Prevent Enteric and Respiratory Viruses in Children RFA-IP-21-002 Closed
Promoting the Importance of Infant and Childhood Vaccination Among Pregnant Women by Prenatal Care Providers RFA-IP-21-001 Closed
Strengthening Federal Ministry of Health Capabilities in Technical Assistance for Service Delivery and Execution of Core Public Health Functions to Achieve and Sustain HIV Epidemic Control in Ethiopia, under PEPFAR CDC-RFA-GH20-2030 Closed
Improving adult vaccination coverage through partnerships with providers and national organizations CDC-RFA-IP20-2002 Closed
Network of Modeling Centers to Improve Evidence Base for Seasonal and Pandemic Influenza Prevention and Control RFA-IP-20-003 Closed
Epidemiology, Prevention, and Treatment of Influenza and Other Respiratory Infections in Panama and Other Countries in the Americas RFA-IP-20-001 Closed
Understanding and Improving Immunization Services among Adult Hospital Inpatient and Observation/Clinical Decision Unit Settings RFA-IP-19-003 Closed
Cooperative Agreement with The Pan American Health Organization (PAHO): Protecting and Strengthening Immunization Programs in The Americas CDC-RFA-GH19-1901 Closed
Promoting, Strengthening and Enhancing Disease Prevention by Collaboration with Targeted Stakeholders CDC-RFA-IP18-1804 Closed
Support for Global Immunization Activities in Complex Settings CDC-RFA-GH18-1848 Closed
Support for Activities to Eradicate Polio, Accelerate Control of Measles and Rubella with United Nations Children's Fund (UNICEF) CDC-RFA-GH18-1804 Closed
Program Expansion Supplement to Cooperative Agreement on Immunization with the World Health Organization (WHO) CDC-RFA-GH13-13010501SUPP18 Closed
Polio Eradication and Emergency Response in Priority Countries, Center for Global Health Immunization Division CDC-RFA-GH16-172104CONT18 Closed
National Organization to Strengthen and Support a Network of Immunization Program Managers CDC-RFA-IP17-1703 Closed
Centers for Disease Control and Prevention Enhanced Surveillance for New Vaccine Preventable RFA-IP-16-00402CONT17 Closed
Centers for Disease Control and Prevention US Platform to Measure Influenza Vaccine Effectiveness against Laboratory-confirmed Influenza-Associated Hospitalizations RFA-IP-15-00203CONT17 Closed
Centers for Disease Control and Prevention Annual Estimates of Influenza Vaccine Effectiveness for Preventing Medically Attended Laboratory- Confirmed Influenza in the United States RFA-IP-16-00202CONT17 Closed
Polio Eradication and Emergency Response in Priority Countries CDC-RFA-GH16-172103CONT17 Closed
Economics, finance, and budgetary evidence to support sustainable financing, planning, and decision-making for immunization programs CDC-RFA-GH16-160302CONT17 Closed
Improving HPV Vaccination Coverage Among Adolescent Patients: A Randomized Controlled Trial of AFIX and Remote Physician-to-Physician Engagement Strategies RFA-IP-17-002 Closed
Polio Eradication and Emergency Response in Priority Countries CDC-RFA-GH16-1721 Closed
Enhanced Surveillance for New Vaccine Preventable Diseases RFA-IP-16-004 Closed
Annual Estimates of Influenza Vaccine Effectiveness for Preventing Medically Attended Laboratory-Confirmed Influenza in the United States RFA-IP-16-002 Closed
National Stop Transmission of Polio (NSTOP) initiative supporting polio eradication in Africa CDC-RFA-GH15-161202CONT16 Closed
Protecting the Advances in Polio, Rubella and Measles Elimination: Strengthening Immunization Programs in the Americas. CDC-RFA-GH14-140103CONT16 Closed
Poliomyelitis Eradication Initiative and Expanded Programme On Immunization CDC-RFA-GH13-130104CONT16 Closed
Support for Activities to Eradicate Polio, Accelerate control of measles and rubella CDC-RFA-GH13-130204CONT16 Closed
Global Measles Elimination CDC-RFA-IP11-110505CONT16 Closed
Show 39 more

Latest 49 listed here. See the rest on GovTribe.

Grant awards

Award Recipient Federal obligations Awarded
Strengthening vaccine-preventable disease prevention and response - the strengthening vaccine-preventable disease… NH23IP922710 Department Of State Health Services $57,467,548
Trusted school messengers promoting non-mandated vaccination U48DP006851 University Of Rochester $2,999,712
The application for funding herein will continue support and capacity building for epidemiology, lab and surveillance… NU51CK000374 Department Of Health $798,876
Pennsylvania department of health - epidemiology and laboratory capacity for prevention and control of emerging… NU51CK000354 Pennsylvania Department Of Health $3,474,222
Epidemiology and laboratory capacity for prevention and control of emerging infectious diseases (ELC)… NU51CK000347 West Virginia State Health Department $8,066,263
IP23-006 vimp: a discourse-aware, community-informed toolkit to predict virality and impact of vaccine misinformation… U01IP001214 University Of Pittsburgh - Of The Commonwealth System Of Higher Education $5,837,943
Emerging infections program - the CDC's emerging infections program (EIP) aligns with the capacity, strengths, and… NU50CK000647 Michigan Department Of Health And Human Services $14,085,073
The washington state department of health aims to support the national emerging infections program (EIP) by… NU50CK000642 Washington State Department Of Health $22,140,605
Epistorm: center for advanced epidemic analytics and predictive modeling technology NU38FT000013 Northeastern University $28,301,592
Enhancing outbreak analytics and forecasting with electronic health records NU38FT000007 Kaiser Foundation Hospitals $44,774,110

Latest 10 of 251 listed here. See the rest on GovTribe.

Top recipients by federal obligations

Rank Recipient Federal obligations Share
1 World Health Organization $599,255,024 16%
2 Unicef $439,869,336 12%
3 Ohio Department Of Health $338,850,112 9%
4 Washington State Department Of Health $254,840,508 7%
5 Indiana Department Of Health $198,842,976 5%
6 State Of Wisconsin Department Of Health Services $188,279,632 5%
7 Oregon Health Authority-Public Health $126,384,480 3%
8 Health Services Kentucky Cabinet For $125,186,504 3%
9 The Task Force For Global Health, Inc. $116,043,808 3%
10 Kansas Department Of Health & Environment $102,541,192 3%

10 of 108 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 -$68,361,387
FY2025 $40,047,699
FY2024 $225,124,866
FY2023 $270,756,211
FY2022 $330,385,395
FY2021 $226,680,264
FY2020 $230,890,092
FY2019 $120,106,741
FY2018 $80,696,279
FY2017 $127,400,963
FY2016 $125,127,682
FY2015 $123,121,394
FY2014 $122,144,504
FY2013 $106,826,706
FY2012 $128,440,551
FY2011 $132,692,025
FY2010 $143,750,991
FY2009 $133,529,524
FY2008 $186,491,252
FY2007 $10,198,043
FY2006 $1,374,558
FY2005 $577,967
FY2004 $95,000
FY2003 $5,444,956
FY2002 -$681,319
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Quick answers

What is Assistance Listing 93.185?

Assistance Listing 93.185 is Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects?

Its CFDA number is 93.185: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.185 awarded?

251 grant awards under 93.185 have obligated $3,675,701,311 in federal funds to 108 recipients.

Who receives the most funding from 93.185?

The recipients obligated the most under Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects are World Health Organization ($599,255,024), Unicef ($439,869,336) and Ohio Department Of Health ($338,850,112).

How much did 93.185 obligate in fiscal year 2025?

Grants under 93.185 obligated $40,047,699 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.185?

2 of the latest 49 opportunities under 93.185 are open or forecasted. The latest, Informing global polio eradication efforts through innovative modeling approaches, was posted on August 31, 2026.

On GovTribe

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