Public Health Foundation Enterprises, Inc.

Public Health Foundation Enterprises, Inc., doing business as Heluna Health, is a California-based nonprofit that serves as a prime recipient on federal research grants and as a fiscal intermediary and subcontractor on state and federal grant programs, delivering public health research administration, grant fiscal management, workforce development, and community health intervention services across 48 federal agencies. The vendor operates predominantly in the grant space rather than federal contracting—146 of 280 total awards are prime (52%), but most prime activity consists of research grants from the National Institutes of Health, the Centers for Disease Control and Prevention, and the National Institute on Drug Abuse, with a smaller contract footprint anchored on a GSA Multiple Award Schedule vehicle (Federal Supply Schedule GS35F0569P) for management consulting and administrative labor.

Heluna Health's research grant capability centers on public health epidemiology, HIV prevention and care, substance use disorder intervention development and testing, infectious disease surveillance, and behavioral health workforce training. Recent prime grants include a $3.12 million NIDA award (CFDA 93.279, Drug Use and Addiction Research Programs, September 30, 2025–May 31, 2030) for the B-SAFE behavioral intervention study addressing unintentional fentanyl use among stimulant users in San Francisco; a $1.939 million NIDA Cooperative Agreement (CFDA 93.279, September 1, 2025–August 31, 2027) for a two-phase clinical trial of semaglutide as a treatment for methamphetamine use disorder; a $659,242 NIMH grant (CFDA 93.242, Mental Health Research Grants, March 5, 2026–November 30, 2030) for the PrEP Blueprint project, developing and evaluating implementation toolkits to improve PrEP uptake in sexual health and infectious disease clinics in San Francisco and Birmingham; a $1 million Health Resources and Services Administration award (CFDA 93.732, Mental and Behavioral Health Education and Training Grants, September 1, 2025–August 31, 2029) to develop a two-level Community Mental Health Worker training and certification program in California's Inland Empire; and a $588,669 NIDA project grant (CFDA 93.279, April 15, 2026–January 31, 2031) for the Street Prep intervention, expanding low-barrier PrEP delivery to people who use drugs and experience homelessness in San Francisco. Heluna Health also holds a $1 million federal supply schedule seat on the GSA Multiple Award Schedule (awarded January 9, 2023, expiring January 8, 2028) offering eight labor categories in administrative, project management, data management, and HR roles at hourly rates from $47.29 to $90.17, with services delivered to CDC, the Department of Health and Human Services, and the National Institutes of Health.

Customer concentration skews heavily toward health agencies. The top five customer agencies by award count account for 47% of all awards: the Department of Agriculture Food and Nutrition Service (35 awards), CDC (30 awards), NIDA (26 awards), CDC Office of Acquisition Services (22 awards), and the National Institutes of Health broadly (19 awards). By combined potential value, CDC programs and NIDA grants dominate; CDC Pittsburgh-based awards carry $40 million combined potential value across four awards, and CDC Office of Acquisition Services awards total $16.7 million across 12 awards. Heluna Health also serves as a fiscal intermediary for state public health programs—it subcontracts heavily with the California Department of Public Health (CDPH), with dozens of sub-grants supporting the WIC program and emerging infectious disease surveillance. Sub-award activity shows Heluna Health performing grant administration and personnel management for CDPH infectious disease and immunization branches, WIC program administration, and contracted research roles as a fiscal sponsor or subcontractor to university research teams at UCSF, UC San Diego, and others.

Within the past five years, Heluna Health has grown its federal grant footprint year over year, from seven awards in 2022 to 51 in 2025. Eight awards carrying combined potential value face ultimate completion dates within the next twenty-four months, representing recompete opportunity. However, the SCI (Service Contract Inventory) dataset captures only one subcontracted service record above the $150,000 federal services threshold, reporting 0.3 FTEs in FY2022; this represents a negligible slice of Heluna Health's actual federal activity and reflects that the vendor's footprint is overwhelmingly grant-funded research and state pass-through administration rather than federal service contracts. The organization is deeply embedded in public health research infrastructure as a fiscal intermediary, contracting partner, and research subcontractor to academic centers and state health departments, with particular strength in HIV/AIDS and substance use disorder research, emerging infectious disease surveillance, and nutrition program administration.