Centers for Research and Demonstration for Health Promotion and Disease Prevention

Active

Assistance listing
93.135
Agency
Grant awards
190 $612,929,957 in federal obligations

Program facts

Also known as
(Prevention Research Centers)
Assistance types
  • Cooperative Agreement
  • Project Grant
  • Block Grant
Treasury account
  • 75-0948-0-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Centers for Disease Control and Prevention (CDC) funds multi-disciplinary academic prevention research centers through CFDA 93.135, with the most recent grant awards issued September 30, 2024. The program establishes, maintains, and operates academic-based centers conducting applied health promotion and disease prevention research with 1- to 5-year project periods; after initial awards, projects may continue non-competitively subject to satisfactory progress and fund availability.

The program has been active for more than two decades, with 190 total awards spanning from 2002 to September 2024. Award activity has fluctuated over the past five years—ranging from 7 awards in 2022 to 26 in 2014—with 14 awards in 2024. The portfolio totals $612.9 million in combined federal obligations. Cooperative Agreements dominate the assistance mix, representing 56% of awards (107), followed by Project Grants at 30% (57) and Block Grants at 14% (26).

CDC's Prevention Research Centers unit is the exclusive funder across the portfolio. The program encompasses surveillance research, behavioral interventions, and implementation research spanning cancer prevention and control, excessive alcohol use epidemiology, vision and eye health surveillance, type 2 diabetes prevention, pediatric weight management, and chronic disease prevention networks. Recent awards illustrate this scope: the University of North Carolina at Chapel Hill received a $2 million award for a cancer prevention and control research network coordinating center; the University of Pennsylvania received $1.2 million for tobacco-related cancer prevention in Hispanic/Latinx communities; and a Michigan telemedicine glaucoma screening program secured $6.75 million.

Eligible applicants are accredited schools of medicine, schools of osteopathy, and schools of public health as defined in the Public Health Service Act. Recipients must retain records for three years beyond project completion or until final audit resolution, whichever is later.

Two recent opportunities are open: RFA-DP-25-126 (due February 28, 2025) solicits Special Interest Project supplements from the 20 currently funded Prevention Research Centers on topics including prostate cancer screening, lung cancer screening, and overdose prevention. RFA-DP-27-030 (posted July 28, 2026) forecasts supplemental funding for similar special projects focused on cancer survivorship, cancer clinical trial enrollment, and hereditary cancer prevention, restricted to the same 20 current centers listed in the opportunity.

Objective and description

Objective

The funded Prevention Research Centers aims are to: 1. Establish, maintain, and operate multi-disciplinary academic-based centers that conduct high-quality applied health promotion and disease prevention research; 2. Improve public health practice th

Description

Funding for Prevention Research Centers to establish, maintain, and operate multi-disciplinary academic-based centers that conduct high-quality applied health promotion and disease prevention research.

Eligibility

Applicant eligibility

Eligible applicants are accredited schools of medicine, schools of osteopathy, and schools of public health as defined in Section 701 (4) of Public Health Service Act.

Beneficiary eligibility

Academic health centers, scientist/researchers, operational public health programs, targeted high risk groups, selected demonstration areas, and the general public.

Uses of assistance

Funds are available for costs directly attributed to the performance of research and demonstration projects pertaining to health promotion and disease prevention plus certain indirect costs of the recipient in accordance with established policies HHS. Recipients may not award surecipients but may enter into consortia agreements or contracts as necessary to achieve the aims of the program.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Prevention Research Center applications are reviewed on the basis of scientific/technical merit, with attention given to such matters as: (1) The degree to which the applicant satisfies the essential requirements and possesses other desired characteristics, such as depth, breadth, and scientific merit of the overall application relative to the types of research and demonstration projects proposed; (2) clarity of purpose and overall qualifications, adequacy and appropriateness of personnel to accomplish proposed prevention research projects and demonstration projects, and the nation's health priorities and needs; (3) ability to generalize, translate and disseminate to State or local health departments, boards of education and other appropriate national regional, and local public health agencies and organizations; (4) reasonableness of the proposed budget in relation to the work proposed.

Award procedure

Approved awards are funded based on priority score ranking from a scientific review, as well as availability of funds, secondary review and such other significant factors deemed necessary and appropriate by the agency. After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, and special conditions, if any.

Deadlines

Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.

Renewals

Project period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.

Grant opportunities

Opportunity Status Posted Applications due
Health Promotion and Disease Prevention Research Centers: 2027 Special Interest Project Supplements (SIPS) RFA-DP-27-030 Forecasted —
Health Promotion and Disease Prevention Research Centers: 2025 Special Interest Project Competitive Supplements (SIPS) RFA-DP-25-126 Closed
Health Promotion and Disease Prevention Research Centers: 2024 Special Interest Project Competitive Supplements (SIPS) RFA-DP-24-062 Closed
Increasing Public Awareness and Provider Education About Primary Immunodeficiency Disease CDC-RFA-CD-23-0057 Closed
Health Promotion and Disease Prevention Research Centers: RFA-DP-24-004 RFA-DP-24-004 Closed
Health Promotion and Disease Prevention Research Centers: 2023 Special Interest Project Competitive Supplement (SIPS) RFA-DP-23-004 Closed
Health Promotion and Disease Prevention Research Centers: 2022 Special Interest Project Competitive Supplements (SIPS) RFA-DP-22-003 Closed
Health Promotion and Disease Prevention Research Centers: 2021 Special Interest Project Competitive Supplements (SIPS) RFA-DP-21-004 Closed
Health Promotion and Disease Prevention Research Centers: 2019 Special Interest Project Competitive Supplements (SIPS) RFA-DP-19-006 Closed
Health Promotion and Disease Prevention Research Centers RFA-DP-19-001 Closed
Health Promotion and Disease Prevention Research Centers: Special Interest Project Competitive Supplements (SIPS) RFA-DP-18-002 Closed
Health Promotion and Disease Prevention Research Centers: Special Interest Project Competitive Supplements (SIPS) RFA-DP-17-005 Closed
SBIR/STTR Commercialization Readiness Pilot (CRP) Program: Technical Assistance (SB1) PAR-16-026 Closed
PPHF 2015: Nutrition, Physical Activity RFA-DP-15-008 Closed
Developing and Disseminating Programs to Build Sustainable Lupus Awareness, Knowledge, Skills and Partnerships CDC-RFA-DP15-1511 Closed
Health Promotion and Disease Prevention Research Centers: Special Interest Project Competitive Supplements (SIPS) RFA-DP-09-001 Closed
Medicaid Expansion and Reproductive Health Care for Women RFA-DP-13-002 Closed
PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) PA-12-088 Closed
Show all 18

Grant awards

Award Recipient Federal obligations Awarded
Health promotion and disease prevention research centers: 2024 special interest project competitive supplements… U48DP006879 University Of South Carolina $1,200,000
Massachusetts cancer prevention and control research network U48DP006873 President And Fellows Of Harvard College $1,788,673
SIP 24-003 cancer prevention and control research network (CPCRN) coordinating & collaborating centers at the… U48DP006872 University Of North Carolina At Chapel Hill $2,024,997
Prevention research centers' cancer prevention and control research network: upenn prevention research center U48DP006865 The Trustees Of The University Of Pennsylvania $1,199,744
Patient perspectives on relabeling and pathology reporting for grade group 1 prostate cancer U48DP006853 The Regents Of The University Of California. San Francisco $1,750,000
SIP-24-003 cancer prevention and control research network (CPCRN) U48DP006841 Emory University $2,100,000
UI cancer prevention and control research network collaborating center U48DP006840 The University Of Iowa $2,100,000
Implementing a culturally appropriate digital health intervention to reduce tobacco-related cancer disparities among… U48DP006835 Georgia State University Research Foundation Inc. $1,500,000
Understanding the impact of survivorship care plans on health outcomes in cancer survivors U48DP006834 Regents Of The University Of Minnesota $1,049,850
Coordinating center for sight studies evaluating the effectiveness of telehealth-based programs to detect glaucoma… U01DP006892 The Trustees Of Columbia University In The City Of New York $2,490,000

Latest 10 of 190 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 78 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $3,775,776
FY2025 $13,757,624
FY2024 $66,098,049
FY2023 $59,824,011
FY2022 $91,616,817
FY2021 $42,145,052
FY2020 $53,325,135
FY2019 $25,122,837
FY2018 $29,040,506
FY2017 $31,988,072
FY2016 $31,862,010
FY2015 $31,100,344
FY2014 $29,423,158
FY2013 $20,900,519
FY2012 $29,811,647
FY2011 $32,203,836
FY2010 $50,307,018
FY2009 $63,514,164
FY2008 $2,799,598
FY2007 $44,002,935
FY2006 $18,102,723
FY2005 $765,500
FY2004 $350,000
FY2003 $5,113,060
FY2002 $9,121,446
Show all 25

Quick answers

What is Assistance Listing 93.135?

Assistance Listing 93.135 is Centers for Research and Demonstration for Health Promotion and Disease Prevention, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Centers for Research and Demonstration for Health Promotion and Disease Prevention?

Its CFDA number is 93.135: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.135 awarded?

190 grant awards under 93.135 have obligated $612,929,957 in federal funds to 78 recipients.

Who receives the most funding from 93.135?

The recipients obligated the most under Centers for Research and Demonstration for Health Promotion and Disease Prevention are Emory University ($56,524,841), University Of North Carolina At Chapel Hill ($51,629,817) and University Of Alabama At Birmingham ($35,117,390).

How much did 93.135 obligate in fiscal year 2025?

Grants under 93.135 obligated $13,757,624 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.135?

1 listed opportunity under 93.135 is open or forecasted. The latest, Health Promotion and Disease Prevention Research Centers: 2027 Special Interest Project Supplements (SIPS), was posted on July 28, 2026.

On GovTribe

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