Centers for Research and Demonstration for Health Promotion and Disease Prevention
Active
- Assistance listing
- 93.135
- Agency
-
Centers for Disease Control and Prevention
Department of Health and Human Services
- Grant awards
- 190 $612,929,957 in federal obligations
Program facts
- Also known as
- (Prevention Research Centers)
- Assistance types
-
- Cooperative Agreement
- Project Grant
- Block Grant
- Treasury account
-
- 75-0948-0-1-550
- More information
Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.
About this program
The Centers for Disease Control and Prevention (CDC) funds multi-disciplinary academic prevention research centers through CFDA 93.135, with the most recent grant awards issued September 30, 2024. The program establishes, maintains, and operates academic-based centers conducting applied health promotion and disease prevention research with 1- to 5-year project periods; after initial awards, projects may continue non-competitively subject to satisfactory progress and fund availability.
The program has been active for more than two decades, with 190 total awards spanning from 2002 to September 2024. Award activity has fluctuated over the past five years—ranging from 7 awards in 2022 to 26 in 2014—with 14 awards in 2024. The portfolio totals $612.9 million in combined federal obligations. Cooperative Agreements dominate the assistance mix, representing 56% of awards (107), followed by Project Grants at 30% (57) and Block Grants at 14% (26).
CDC's Prevention Research Centers unit is the exclusive funder across the portfolio. The program encompasses surveillance research, behavioral interventions, and implementation research spanning cancer prevention and control, excessive alcohol use epidemiology, vision and eye health surveillance, type 2 diabetes prevention, pediatric weight management, and chronic disease prevention networks. Recent awards illustrate this scope: the University of North Carolina at Chapel Hill received a $2 million award for a cancer prevention and control research network coordinating center; the University of Pennsylvania received $1.2 million for tobacco-related cancer prevention in Hispanic/Latinx communities; and a Michigan telemedicine glaucoma screening program secured $6.75 million.
Eligible applicants are accredited schools of medicine, schools of osteopathy, and schools of public health as defined in the Public Health Service Act. Recipients must retain records for three years beyond project completion or until final audit resolution, whichever is later.
Two recent opportunities are open: RFA-DP-25-126 (due February 28, 2025) solicits Special Interest Project supplements from the 20 currently funded Prevention Research Centers on topics including prostate cancer screening, lung cancer screening, and overdose prevention. RFA-DP-27-030 (posted July 28, 2026) forecasts supplemental funding for similar special projects focused on cancer survivorship, cancer clinical trial enrollment, and hereditary cancer prevention, restricted to the same 20 current centers listed in the opportunity.
Objective and description
- Objective
The funded Prevention Research Centers aims are to: 1. Establish, maintain, and operate multi-disciplinary academic-based centers that conduct high-quality applied health promotion and disease prevention research; 2. Improve public health practice th
- Description
Funding for Prevention Research Centers to establish, maintain, and operate multi-disciplinary academic-based centers that conduct high-quality applied health promotion and disease prevention research.
Eligibility
- Applicant eligibility
Eligible applicants are accredited schools of medicine, schools of osteopathy, and schools of public health as defined in Section 701 (4) of Public Health Service Act.
- Beneficiary eligibility
Academic health centers, scientist/researchers, operational public health programs, targeted high risk groups, selected demonstration areas, and the general public.
- Uses of assistance
Funds are available for costs directly attributed to the performance of research and demonstration projects pertaining to health promotion and disease prevention plus certain indirect costs of the recipient in accordance with established policies HHS. Recipients may not award surecipients but may enter into consortia agreements or contracts as necessary to achieve the aims of the program.
- Length and time phasing of assistance
Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.
How to apply
- Criteria for selecting proposals
Prevention Research Center applications are reviewed on the basis of scientific/technical merit, with attention given to such matters as: (1) The degree to which the applicant satisfies the essential requirements and possesses other desired characteristics, such as depth, breadth, and scientific merit of the overall application relative to the types of research and demonstration projects proposed; (2) clarity of purpose and overall qualifications, adequacy and appropriateness of personnel to accomplish proposed prevention research projects and demonstration projects, and the nation's health priorities and needs; (3) ability to generalize, translate and disseminate to State or local health departments, boards of education and other appropriate national regional, and local public health agencies and organizations; (4) reasonableness of the proposed budget in relation to the work proposed.
- Award procedure
Approved awards are funded based on priority score ranking from a scientific review, as well as availability of funds, secondary review and such other significant factors deemed necessary and appropriate by the agency. After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, and special conditions, if any.
- Deadlines
Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.
- Renewals
Project period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.
Grant opportunities
Show all 18
Grant awards
Latest 10 of 190 listed here. See the rest on GovTribe.
Top recipients by federal obligations
| Rank | Recipient | Federal obligations | Share |
|---|---|---|---|
| 1 | Emory University | $56,524,841 | 9% |
| 2 | University Of North Carolina At Chapel Hill | $51,629,817 | 8% |
| 3 | University Of Alabama At Birmingham | $35,117,390 | 6% |
| 4 | Regents Of The University Of Michigan | $33,697,218 | 5% |
| 5 | University Of Washington | $27,550,738 | 4% |
| 6 | Regents Of The University Of Minnesota | $24,739,745 | 4% |
| 7 | University Of Massachusetts Medical School | $19,497,558 | 3% |
| 8 | The Trustees Of Columbia University In The City Of New York | $18,886,675 | 3% |
| 9 | University Of Texas Health Science Center At Houston | $16,370,606 | 3% |
| 10 | The Regents Of The University Of California. San Francisco | $14,826,517 | 2% |
10 of 78 recipients listed here. See the rest on GovTribe.
Federal obligations by fiscal year
| Fiscal year | Federal obligations |
|---|---|
| FY2026 | $3,775,776 |
| FY2025 | $13,757,624 |
| FY2024 | $66,098,049 |
| FY2023 | $59,824,011 |
| FY2022 | $91,616,817 |
| FY2021 | $42,145,052 |
| FY2020 | $53,325,135 |
| FY2019 | $25,122,837 |
| FY2018 | $29,040,506 |
| FY2017 | $31,988,072 |
| FY2016 | $31,862,010 |
| FY2015 | $31,100,344 |
| FY2014 | $29,423,158 |
| FY2013 | $20,900,519 |
| FY2012 | $29,811,647 |
| FY2011 | $32,203,836 |
| FY2010 | $50,307,018 |
| FY2009 | $63,514,164 |
| FY2008 | $2,799,598 |
| FY2007 | $44,002,935 |
| FY2006 | $18,102,723 |
| FY2005 | $765,500 |
| FY2004 | $350,000 |
| FY2003 | $5,113,060 |
| FY2002 | $9,121,446 |
Show all 25
Quick answers
What is Assistance Listing 93.135?
Assistance Listing 93.135 is Centers for Research and Demonstration for Health Promotion and Disease Prevention, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).
What is the CFDA number for Centers for Research and Demonstration for Health Promotion and Disease Prevention?
Its CFDA number is 93.135: Assistance Listing numbers were called CFDA numbers before 2018.
How much funding has Assistance Listing 93.135 awarded?
190 grant awards under 93.135 have obligated $612,929,957 in federal funds to 78 recipients.
Who receives the most funding from 93.135?
The recipients obligated the most under Centers for Research and Demonstration for Health Promotion and Disease Prevention are Emory University ($56,524,841), University Of North Carolina At Chapel Hill ($51,629,817) and University Of Alabama At Birmingham ($35,117,390).
How much did 93.135 obligate in fiscal year 2025?
Grants under 93.135 obligated $13,757,624 in federal funds in fiscal year 2025.
Are there open grant opportunities under 93.135?
1 listed opportunity under 93.135 is open or forecasted. The latest, Health Promotion and Disease Prevention Research Centers: 2027 Special Interest Project Supplements (SIPS), was posted on July 28, 2026.
On GovTribe
See this program's full record
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