Biological Sciences

Inactive

Assistance listing
47.074
Agency
Grant awards
46,767 $18,251,818,057 in federal obligations

Program facts

Assistance types
  • Project Grant
  • Cooperative Agreement

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The National Science Foundation's Biological Sciences program (CFDA 47.074) funds foundational basic research across the biological sciences through predominantly Project Grants, with the most recent grant award issued on March 1, 2027.

NSF is the sole significant funder under this program, accounting for $11.57 billion of the $18.25 billion in combined federal obligations across 46,767 awards since 1991. Within NSF, four divisions drive activity: the Division of Integrative Organismal Systems ($1.65 billion across 2,329 awards), the Division of Biological Infrastructure ($1.54 billion across 1,671 awards), the Division of Molecular and Cellular Biosciences ($1.34 billion across 1,921 awards), and the Division of Environmental Biology ($1.28 billion across 2,214 awards). Project Grants comprise 99 percent of the portfolio, with Cooperative Agreements representing the remaining one percent.

Program activity has slowed markedly in recent years. Awards peaked at 1,073 per year in 2023 but declined to 781 in 2025, 555 in 2026, and only 27 in the first quarter of 2027—indicating either a reduction in submission volume, a shift in funding allocation strategy, or a gap in award processing. Awarded research spans host-microbe interactions (REU Site at University of Iowa on microbiology at the host-pathogen interface, $441,657), evolutionary mechanisms (collaborative research on gut microbiota in wild mammals, $434,617 and $838,435), bioinformatic infrastructure (EukPhylo phylogenomic platform, $736,602), and ecological resilience (wild bee response to heat waves across multiple sites, with awards ranging from $174,877 to $570,713).

Recent grant opportunities reflect NSF's current research priorities. The Core Research in Biological Sciences (BIO Core) solicitation (26-517, due October 5, 2076—note: deadline appears incorrectly dated) and the Ecology and Evolution of Infectious Diseases program (24-592) remain active. The Postdoctoral Research Fellowships in Biology program (26-504, due September 28, 2027) emphasizes artificial intelligence applied to biological research. Organismal Response to Climate Change (22-513) and Division of Environmental Biology core programs (22-541) support ecological and evolutionary research. None of the solicitations currently open carry application deadlines in the immediate weeks ahead.

Objective and description

Objective

To promote the progress of the biological sciences and thereby strengthen the Nation's scientific enterprise; to increase scientific knowledge and enhance understanding of major problems confronting the Nation. Most of the research supported is basic

Grant opportunities

Opportunity Status Posted Applications due
Quantum Leap Challenge Institutes (QLCI) 24-599 — —
Science and Technology Centers: Integrative Partnerships 22-521 — —
Strengthening American Infrastructure (SAI) 25-534 — —
Science and Technology Centers: Integrative Partnerships 24-594 — —
Data Science Corps (DSC) 24-560 — —
Incorporating Human Behavior in Epidemiological Models (IHBEM) 25-538 — —
Core Research in Biological Sciences (BIO Core) 26-517 — —
Emerging Mathematics in Biology (eMB) 25-509 — —
Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) 26-512 Open
Pathways to Enable Secure Open-Source Ecosystems (PESOSE) 26-506 Open
National Quantum and Nanotechnology Infrastructure (NQNI) 26-505 Closed
Postdoctoral Research Fellowships in Biology (PRFB) 26-504 Open
Accelerating Research Translation 25-548 Closed
National Science Foundation National Innovation Corps Teams (NSF National I-CorpsTM Teams) Program 25-549 — —
Test Bed: Toward a Network of Programmable Cloud Laboratories 25-541 Closed
Test Bed: Toward a Network of Programmable Cloud Laboratories 25-541 Closed
National Science Foundation Translation to Practice (NSF TTP) 25-540 Open
Ethical and Responsible Research 22-526 — —
Research Coordination Networks in Undergraduate Biology Education 22-522 — —
Organismal Response to Climate Change 22-513 — —
Ecology and Evolution of Infectious Diseases 21-609 — —
Ecology and Evolution of Infectious Diseases 24-592 — —
Division of Environmental Biology 22-541 — —
Pathways to Enable Open-Source Ecosystems 23-556 — —
Plant Genome Research Program 23-559 — —
Long-Term Ecological Research 22-543 — —
Leading Culture Change Through Professional Societies of Biology 22-542 — —
Division of Environmental Biology 21-504 — —
Infrastructure Innovation for Biological Research 21-502 — —
Infrastructure Capacity for Biological Research 21-501 — —
Division of Molecular and Cellular Biosciences Core Programs 21-509 — —
Division of Integrative Organismal Biology Core Programs 21-506 — —
Plant Genome Research Program 21-507 — —
Research Coordination Networks (RCN) 15-527 — —
Dynamics of Integrated Socio-Environmental Systems 14-601 — —
Accelerating Research through International Network-to-Network Collaborations 21-511 — —
Science of Learning PD-07-7278 — —
Workplace Equity for Persons with Disabilities in STEM and STEM Education 23-593 — —
Transitions to Excellence in Molecular and Cellular Biosciences Research 20-505 — —
Division of Environmental Biology 20-502 — —
Grant Opportunities for Academic Liaison with Industry 12-513 — —
Software Infrastructure for Sustained Innovation 15-553 — —
Faculty Early Career Development Program 20-525 — —
NSF Innovation Corps Hubs Program 20-529 — —
Division of Integrative Organismal Biology Core Programs 20-536 — —
Enabling Discovery through GEnomics 20-532 — —
Research Experiences for Teachers Sites in Biological Sciences 21-584 — —
ADVANCE: Organizational Change for Gender Equity in STEM Academic Professions 20-554 — —
Industry-University Cooperative Research Centers Program 20-570 — —
Established Program to Stimulate Competitive Research (EPSCoR): Workshop Opportunities 19-588 — —
Show 40 more

Latest 50 listed here. See the rest on GovTribe.

Grant awards

Award Recipient Federal obligations Awarded
REU site: microbiology at the host-pathogen interface 2548170 The University Of Iowa $441,657
Collaborative research: linking GUT microbiota to host nutrient dynamics, physiological performance, and survival in… 2620840 University Of California, Merced $335,945
Collaborative research: linking GUT microbiota to host nutrient dynamics, physiological performance, and survival in… 2620839 University Of Illinois $434,617
Collaborative research: linking GUT microbiota to host nutrient dynamics, physiological performance, and survival in… 2620838 University Of New Mexico $838,435
RUI: enabling phylogenomic research on microbial eukaryotes with eukphylo 2620734 The Trustees Of The Smith College $736,602
Star: ECO-evolutionary drivers of viral spillover: integrating long-term data and scientific collections 2620646 Virginia Polytechnic Institute & State University $400,000
Collaborative research: group structure, hydrodynamics, and sensing of squids during collective swimming 2602821 University Of North Texas $511,338
Collaborative research: group structure, hydrodynamics, and sensing of squids during collective swimming 2602820 Franklin And Marshall College $245,171
Collaborative research: group structure, hydrodynamics, and sensing of squids during collective swimming 2602819 Southern Methodist University $103,632
Collaborative research: group structure, hydrodynamics, and sensing of squids during collective swimming 2602818 Old Dominion University Research Foundation $638,784

Latest 10 of 46,767 listed here. See the rest on GovTribe.

Top recipients by federal obligations

Rank Recipient Federal obligations Share
1 Battelle Memorial Institute $882,831,321 5%
2 National Ecological Observatory Network, Inc. $418,880,296 2%
3 Cornell University $341,263,347 2%
4 Michigan State University $325,649,964 2%
5 University Of California, Davis $277,751,991 2%
6 University Of Wisconsin System $274,250,013 2%
7 University Of Arizona $268,371,264 1%
8 University Of Florida $246,288,901 1%
9 University Of Georgia Research Foundation, Inc. $241,941,146 1%
10 Duke University $220,057,397 1%

10 of 1,103 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $480,462,861
FY2025 $775,357,015
FY2024 $782,974,802
FY2023 $806,554,435
FY2022 $833,976,405
FY2021 $852,946,220
FY2020 $819,440,208
FY2019 $792,841,505
FY2018 $752,695,097
FY2017 $779,929,078
FY2016 $832,045,331
FY2015 $747,220,317
FY2014 $809,405,339
FY2013 $755,641,179
FY2012 $753,105,739
FY2011 $740,270,552
FY2010 $724,145,958
FY2009 $678,410,498
FY2008 $644,477,503
FY2007 $635,100,446
FY2006 $582,360,713
FY2005 $575,042,031
FY2004 $374,807,960
FY2003 $547,509,048
FY2002 $441,879,469
FY2001 $415,989,668
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Quick answers

What is Assistance Listing 47.074?

Assistance Listing 47.074 is Biological Sciences, a federal grant program run by National Science Foundation. It is inactive.

What is the CFDA number for Biological Sciences?

Its CFDA number is 47.074: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 47.074 awarded?

46,767 grant awards under 47.074 have obligated $18,251,818,057 in federal funds to 1,103 recipients.

Who receives the most funding from 47.074?

The recipients obligated the most under Biological Sciences are Battelle Memorial Institute ($882,831,321), National Ecological Observatory Network, Inc. ($418,880,296) and Cornell University ($341,263,347).

How much did 47.074 obligate in fiscal year 2025?

Grants under 47.074 obligated $775,357,015 in federal funds in fiscal year 2025.

Are there open grant opportunities under 47.074?

4 of the latest 50 opportunities under 47.074 are open or forecasted. The latest, Quantum Leap Challenge Institutes (QLCI), was posted on October 9, 2026.

On GovTribe

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