Ecology and Evolution of Infectious Diseases

Posted

Opportunity number
24-592
Agency
Applications due
Not on record
Award size
$1,500,000 to $3,000,000

Opportunity facts

Assistance listings
Funding instrument
Grant
Category
  • Science and Technology and other Research and Development
Eligible applicants
  • Other
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Science Foundation (NSF) and the Department of Health and Human Services' National Institutes of Health (NIH) are jointly offering the Ecology and Evolution of Infectious Diseases grant opportunity. This program supports interdisciplinary research to understand the ecological, evolutionary, and social drivers of infectious disease transmission dynamics across host species, including humans, animals, and plants. Proposals should focus on quantitative, mathematical, or computational modeling of pathogen (re)emergence and transmission, and may address zoonotic, vector-borne, or environmental diseases of public health or agricultural concern, particularly in low- and middle-income countries. Key evaluation criteria include the proposal's potential to elucidate principles of infectious disease systems and its integration of diverse expertise, such as from anthropology, epidemiology, ecology, and social sciences. The application deadline is September 15, 2025.

Typical grant awards range from $50,000 to over $1 million, with project periods of 1-5 years. Research is expected to be conducted primarily at academic institutions, research facilities, and field sites across the United States and collaborating international partner countries.

Synopsis

The multi-agency Ecology and Evolution of Infectious Diseases program supports research on the ecological, evolutionary, organismal, and social drivers that influence the transmission dynamics of infectious diseases. The central theme of submitted projects must be the quantitative, mathematical, or computational understanding of pathogen transmission dynamics. The intent is discovery of principles of infectious disease (re)emergence and transmission and testing mathematical or computational models that elucidate infectious disease systems. Projects should be broad, interdisciplinary efforts that go beyond the scope of typical studies. They should focus on the determinants and interactions of (re)emergence and transmission among any host species, including but not limited to humans, non-human animals, and/or plants. This includes, for example, the spread of pathogens; the influence of environmental factors such as climate; the population dynamics and genetics of vectors and reservoir species or hosts; how the physiology or behavior of the pathogen, vector, or host species biology affects transmission dynamics; the feedback between ecological transmission and evolutionary dynamics; and the cultural, social, behavioral, and economic dimensions of pathogen transmission and disease. Research may be on zoonotic, environmentally-borne, vector-borne, enteric, or respiratory pathogens of either terrestrial, aquatic, or marine systems and organisms, including diseases of animals and plants, at any scale from specific pathogens to inclusive environmental systems. Proposals for research on disease systems of public health concern toLow- or Middle-Income Countries (LMICs) are strongly encouraged, as are disease systems of concern in agricultural systems. Investigators are encouraged to develop the appropriate multidisciplinary team, including for example, anthropologists, modelers, ecologists, bioinformaticians, genomics researchers, social scientists, economists, oceanographers, mathematical scientists, behaviorists, epidemiologists, evolutionary biologists, entomologists, immunologists, parasitologists, microbiologists, bacteriologists, virologists, pathologists or veterinarians, with the goal of integrating knowledge across disciplines to enhance our ability to predict and control infectious diseases.

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