Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

Open Posted

Opportunity number
PAR-25-378
Agency
Applications due
Award size
Not on record

Opportunity facts

Funding instrument
Grant
Categories
  • Income Security and Social Services
  • Environment
  • Health
  • Education
Eligible applicants
  • For Profit Organizations
  • County Governments
  • Independent School Districts
  • Small Businesses
  • Other
  • Higher Education Inst. (Private)
  • City/Township Governments
  • Tribal Governments (Federally Recognized)
  • Non-501(c)(3) Nonprofits
  • 501(c)(3) Nonprofits
  • Special District Governments
  • Higher Education Inst. (Public)
  • State Governments
  • Public or Indian Housing Auth.
  • Tribal Organizations (Not Federally Recognized)
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health is soliciting applications for intervention research to improve health in Native American populations, with applications due January 7, 2027. The opportunity supports etiologic research that informs intervention development, research developing or testing health promotion and disease prevention interventions, research testing culturally informed treatment or recovery interventions, and dissemination and implementation research on strategies to overcome adoption and scale-up barriers for effective interventions. Research must focus on Alaska Natives and American Indians whose ancestral lands fall at least partially within the U.S. mainland, and interventions must be designed with sustainability and adaptability across communities in view.

Eligible applicants include for-profit and nonprofit organizations, tribal governments (federally recognized and non-federally recognized), higher education institutions, state and local government units, small businesses, independent school districts, housing authorities, and faith-based or community-based organizations. Non-domestic (non-U.S.) entities are not eligible; however, foreign components of U.S. organizations are permitted. Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions, historically Black colleges and universities, Hispanic-serving institutions, and tribally controlled colleges and universities are among eligible applicant categories.

The NOFO is assigned to multiple NIH Assistance Listings: 93.313 (NIH Office of Research on Women's Health), 93.310 (Trans-NIH Research Support), 93.242 (Mental Health Research Grants), 93.273 (Alcohol Research), 93.279 (Drug Use and Addiction Research), 93.113 (Environmental Health), 93.865 (Child Health and Human Development Extramural Research), 93.121 (Oral Diseases and Disorders Research), 93.361 (Nursing Research), 93.213 (Complementary and Integrative Health), and 93.866 (Aging Research). Award amounts, period of performance length, and specific evaluation criteria are not stated in the source materials provided.

Synopsis

3 versions

Update #3 · Latest ·

The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land).

Update #2 ·

Closed -

Not available

Update #1 ·

The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land).

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Files

File Type Posted
PAR-25-378-Full-Announcement.html HTML file
PAR-25-378-Full-Announcement.html HTML file
PKG00290284.pdf PDF

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