HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)

Closed Posted

Opportunity number
RFA-DA-25-078
Agency
Applications due
Award size
Not on record

Opportunity facts

Funding instrument
Grant
Categories
  • Education
  • Health
  • Income Security and Social Services
Eligible applicants
  • Tribal Organizations (Not Federally Recognized)
  • Higher Education Inst. (Public)
  • 501(c)(3) Nonprofits
  • Independent School Districts
  • Non-501(c)(3) Nonprofits
  • County Governments
  • Other
  • Small Businesses
  • City/Township Governments
  • Special District Governments
  • Higher Education Inst. (Private)
  • Tribal Governments (Federally Recognized)
  • State Governments
  • For Profit Organizations
  • Public or Indian Housing Auth.
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

This is a Request for Application (RFA) announcement for the HEAL Initiative focused on translational research to address the overdose crisis. The opportunity (RFA-DA-25-078) is administered by the Department of Health and Human Services National Institutes of Health and uses an R61/R33 phased innovation award mechanism with clinical trials being optional. The RFA serves as a parent announcement for the HEAL Initiative Translation to Practice Team, specifically targeting research on overdose deaths and the intersection of pain and Opioid Use Disorder (OUD). It works in conjunction with several Notice of Special Interest (NOSI) announcements covering workforce development, exposure to violence, and leveraging inpatient hospitalizations. The grant opportunity is open to a wide range of applicants including small businesses, government entities, nonprofits, educational institutions, and tribal organizations.

Recent Federal Grant Awards under the relevant programs have ranged from smaller exploratory grants around $50,000 to large multi-year projects exceeding $3 million in total costs, with typical award durations spanning 2-5 years. The research activities are primarily conducted at the facilities of the recipient organizations across the United States. The application deadline for this opportunity is March 20, 2025.

Synopsis

This RFA will act as a parent RFA for the HEAL initiative Translation to Practice Team, specifically encouraging translational dissemination and implementation research focused on addressing overdose deaths and the intersection of pain and OUD. This RFA will function in tandem with targeted NOSIs that announce more specific areas of focus. For FY25, this currently includes the Workforce NOSI, the Exposure to Violence NOSI, and the Leveraging Inpatient Hospitalizations NOSI. It has a companion R33 RFA.

Files

File Type Posted
RFA-DA-25-078-Full-Announcement.html HTML file

On GovTribe

Work this opportunity

  • Track it in your pipeline
  • Find teaming partners
  • Similar grant opportunities
  • Ask GovTribe AI about this opportunity