HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)

Closed Posted

Opportunity number
PAR-25-154
Agency
Applications due
Award size
Up to $100,000

Opportunity facts

Funding instrument
Grant
Categories
  • Education
  • Health
  • Income Security and Social Services
Eligible applicants
  • 501(c)(3) Nonprofits
  • Non-501(c)(3) Nonprofits
  • Higher Education Inst. (Private)
  • City/Township Governments
  • Tribal Organizations (Not Federally Recognized)
  • Tribal Governments (Federally Recognized)
  • Small Businesses
  • State Governments
  • Other
  • Special District Governments
  • Public or Indian Housing Auth.
  • For Profit Organizations
  • County Governments
  • Higher Education Inst. (Public)
  • Independent School Districts
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

This federal grant opportunity, issued by the Department of Health and Human Services' National Institutes of Health (NIH), aims to solicit applications for pilot projects to identify new druggable targets for pain within the understudied druggable proteome. The funding supports generation of preliminary data and tools around eligible understudied proteins, with the goal of jumpstarting research on understudied proteins in the context of pain and pain management. The opportunity is part of the NIH Helping to End Addiction Long Term (HEAL) initiative to accelerate the development of novel medications to treat opioid addiction. Eligible applicants include a wide range of entities such as nonprofits, higher education institutions, small businesses, and government organizations. The proposed research should focus on basic biochemical and/or biological work to further characterize understudied proteins for potential pain management applications.

Award values and durations are not explicitly stated, but recent grants under the related research programs have ranged from smaller exploratory grants around $100,000 to larger multi-year awards exceeding $1 million. The research activities are expected to be conducted at the facilities of the selected award recipients across the United States.

Synopsis

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to identify new druggable targets for pain within the understudied druggable proteome. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s) listed in this NOFO. This NOFO is intended to jumpstart research on understudied proteins within the context of pain and pain management and provide applicants with sufficient funding to perform basic biochemical and/or biological work to further the characterization of understudied proteins to identify new druggable targets for pain. This NOFO is part of the NIH Helping to End Addiction Long Term (HEAL) initiative to accelerate the development of novel medications to treat all aspects of the opioid addiction cycle, including progression to chronic use, withdrawal symptoms, craving, relapse, and overdose.

Files

File Type Posted
PAR-25-154-Full-Announcement.html HTML file

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