Research Study; Mapping Temporal Dynamics of Immune responses in Severe Multisystem and Orthopedic Polytrauma Using single-Cell Multiomics
Closed Special Notice Posted
- Solicitation number
- HT9425-25-NOI-JBC01
- Agency
-
Defense Health Agency
Department of Defense
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Place of performance
- San Antonio, Texas, United States
Notice details come from SAM.gov. Updated .
About this opportunity
The Defense Health Agency has issued a Special Notice concerning a specialized military medical research study to be conducted by the Metis Foundation for the Advancement of Military Medicine. The notice, posted on May 14, 2025, involves a sole source contract opportunity for researching the temporal dynamics of immune responses in severe multisystem and orthopedic polytrauma using single-cell multiomics. This research is being undertaken in support of the U.S. Air Force 59th Medical Wing and will be managed by the U.S. Army Medical Research Acquisition Activity (USAMRAA). The opportunity is categorized under NAICS code 541715 for research and development in physical, engineering, and life sciences, with a PSC Code of AN12 for medical biomedical research. The contract is intended to be awarded without a specific set-aside, indicating broad potential for research collaboration.
The primary objective of this research is to characterize immune responses in polytrauma patients, with specific goals of identifying prognostic indicators, understanding inflammatory syndrome, and exploring potential therapeutic targets. Contractors interested in competing for this opportunity must submit written responses demonstrating their capability by 10:00 AM EST on May 29, 2025. If no competitive responses are received by the deadline, the contract will be awarded exclusively to the Metis Foundation. The study will investigate immune biomarkers and response patterns in patients with and without orthopedic trauma, utilizing advanced single-cell multiomics techniques. Eligibility appears to be open to research organizations with expertise in medical research, particularly those with capabilities in immunology, trauma response, and advanced cellular analysis methodologies. The research represents a critical opportunity to advance understanding of complex medical responses in severe trauma scenarios, potentially offering significant insights for military medical treatment and preparedness.
Notice text
Please see attached Notice of Intent
Files
| File | Type | Posted |
|---|---|---|
| Notice of Intent HT9425-25-NOI-JBC-01.docx | DOCX document |
Notice history
| Notice | Type | Posted |
|---|---|---|
| This notice | Special Notice | |
| Research Study; Mapping Temporal Dynamics of Immune responses in Severe Multisystem and Orthopedic Polytrauma Using single-Cell Multiomics | Pre-Solicitation |
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