Quadrupole-Orbitrap Hybrid Mass Spectrometer

The Food and Drug Administration's Human Foods Program is conducting market research to identify small business concerns capable of supplying and installing a quadrupole-orbitrap hybrid mass spectrometer system for its Division of Analytical Chemistry, Spectroscopy Mass Spectrometry Branch located in College Park, Maryland. The procurement encompasses a newly manufactured, high-performance mass spectrometry system designed to support advanced proteomics research for analyzing complex protein mixtures in FDA-regulated foods and human cell samples. Key contract requirements include delivery and installation by September 30, 2026, system specifications such as 70 Hz acquisition speed, sensitivity below 1.5 femtograms, mass accuracy below 1 ppm, and resolving power of 480,000 at m/z 200, along with support for multiple acquisition modes including data-dependent acquisition, data-independent acquisition, and parallel reaction monitoring. The system must also include three days of on-site instructor-led training, a one-year parts and labor warranty, installation by manufacturer-trained and certified service engineers, trade-in services for existing equipment, and compatible data analysis software. Interested small businesses must submit capability statements demonstrating relevant experience with mass spectrometry systems, equipment installation and integration, and training and service agreements by April 27, 2026, at 10:00 AM Eastern Time to Freshta.Javid@fda.hhs.gov.

This is a pre-solicitation notice with no set-aside designation specified, issued solely for market research and planning purposes and does not constitute a binding solicitation. No incumbent contractor or specific award value has been identified in the available documentation. Qualified small businesses must demonstrate the ability to perform at least 51 percent of the work and fall under NAICS Code 334516 (Analytical Laboratory Instrument Manufacturing) with a size standard of 1,000 employees. The contractor is responsible for delivering the fully integrated instrument system, conducting performance verification, providing required consumables, and optionally supplying an uninterruptible power supply. The total procurement timeline extends from the April 27, 2026 response deadline through the September 30, 2026 delivery and installation requirement, providing approximately five months for system procurement, manufacturing, delivery, and installation.