Meso quickplex SQ 120MM reader

NOTICE OF INTENT TO SOLE SOURCE

NOI-NIAID-25-2249531

NAICS – 334516

This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on other than full and open competition basis with ISS Metro Scale Discovery for the procurement of the MESO Quick Plex Sq 120MM.

The Department of Health and Human Services (DHHS), National Institute of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Extramural Activities (DEA) began a project in 2002 to perform onsite administrative assessments of the administrative operations and procedures of foreign grant recipients and contractors receiving funds from NIAID. The project provides foreign recipients with proper oversight of awards by way of performing onsite international financial systems reviews and provides related administrative technical assistance that supports the NIAID grant, cooperative agreement, and contract awardees.

If any vendor submits a capability statement, the statement must address the following requirements to be considered. Capability statements that do not address each of the bulleted items, will not be considered.

Key Features:

• Single and multiplex assay capability
• Compatible with all SECTOR™ and QuickPlex® products
• Broad assay menu with many commercially available kits
• Full suite of components for user-developed assays
• Access to all MSD® consumables product lines
• Developed under design control
• Compatible with Microsoft Windows 10
• Fast, simple, and secure data analysis via DISCOVERY WORKBENCH® software
• ECL (Electrochemiluminescence) detection for high sensitivity and dynamic range
• Rapid plate read times (as fast as 90 seconds)
• Single-well read mode for enhanced performance
• Compact size — ¼ the footprint of SECTOR® instruments
• Full-featured laptop included
• No fluidics — no clogs or cleaning required
• No daily or monthly user maintenance needed

Instrument Specifications:

• Detection Technology: Electrochemiluminescence (ECL)
• Detection System: Cooled scientific-grade CCD camera with custom lens
• Multiplexing Capability: Up to 10 assays per well
• Plate Compatibility: MSD 96-well SECTOR plates and QuickPlex plates
• Sensitivity: Detection limits as low as 0.05 to 1 pg/mL (varies by assay)
• Dynamic Range: Greater than 10⁵
• Read Time per Plate:
• SECTOR plates: 1 min 30 sec
• QuickPlex plates: 2 min 45 sec
• Throughput:
• SECTOR plates: Up to 40 plates/hour
• QuickPlex plates: Up to 22 plates/hour
• Plate Stack Capacity: 5 input / 5 output plates

The statutory authority for this sole source requirement is 41 U.S.C. 1901 (a) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL.  All responsible sources that could provide comparable services may submit a capability statement that will be considered. The documents must be submitted via the NIAID electronic Simplified Acquisition Submission System (eSASS) website at https://esass.nih.gov, (subject line to reference NOI-NIAID-25-2249531 by 12:00 pm eastern standard time March 27, 2024. All vendors must register in the eSASS system to submit a quotation. Instructions on how to register / submit quotes are included on the website. Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f). All responsible sources may submit an offer that will be considered by this Agency.